histometry of the skin by means of in vivo confocal microscopy

Ngày tải lên: 28/03/2014, 19:21

... ease of use of the internet by participating in training programmes that can enhance their understanding of the usefulness and ease of use of the internet in internationalization, as well as the ... approach The greater the degree of their learning orientation, the greater the degree of “unlearning” these firms will undertake That is, they are likely to withdraw from their routine ways of doing ... for internationalization Perceived ease of use of the internet in the organizational context is the degree to which the internationalizing firm believes that utilizing the internet to obtain relevant...

Ngày tải lên: 03/04/2016, 13:02

... absorption of two infrared photons, rather than by a single photon of visible light as in confocal microscopy Each of the two photons contributes half of the energy required to induce fluorescence The ... resident DCs are labeled in the skin by injecting CSFE together with antigen and adjuvant CSFE+ DCs are then detected after migration in the draining lymph nodes and the interaction with antigenspecific ... a broad flap of abdominal skin or the popliteal lymph nodes of the feet [25] A rubber ring is glued on the inner surface of the exposed skin flap with tissue adhesive Thereby a watertight chamber...

Ngày tải lên: 09/08/2014, 07:20

... constant and ε is the straingauge reading Then, torque failure output was implemented in definition of loading conditions of the simulation of in vivo experimental circumstances using finite element ... test that yielded failure of the bone-implant interface was implemented in definition of loading conditions in the finite element analysis In the definition of loading condition, a centrally ... partial loss of torque resistance of the implant was observed The in vivo torque failure test yielded 5952 μstrains, as determined from the computer software Conversion of in vivo strain data to...

Ngày tải lên: 11/08/2014, 23:22

... We define β (degree of conjugation) as the proportion of BAS that is free of binding proteins and is available to interact with cognate receptors The larger is β, the larger the proportion of "free" ... apparent from the figure, the magnitude and the analytical appearance of in vivo response is affected by the dose of BAS and its degree of conjugation (β) Both the bimodal and biphasic in vivo responses ... therapy and so on [2] But engineered modifications of hormones, growth factors or their analogs are likely to differ from the native analogues in their affinity for binding proteins In view of...

Ngày tải lên: 13/08/2014, 22:22

... the beginning of the region encoding the first zinc finger in exon 2, whereas the mouse generated by Topiliko et al [41] had the lacZ and neomycin genes inserted 50 bp upstream of the Egr-1 initiation ... SP1 binding occupancies change dramatically EGR-1 binding may influence the occupancy of previous binding proteins, resulting in the reconstruction of the transcription factor complex and the induction ... changed near EGR-1 binding sites, suggesting that EGR-1 binding influences the occupancy of previous binding proteins These observations may help explain why EGR-1 binding results in multiple responses...

Ngày tải lên: 14/08/2014, 21:20

Ngày tải lên: 08/08/2012, 17:20

... surface washoff are different depending on the sampling locations and rainfall patterns Time variation of pollutant concentration in road runoff showed increasing trend at the end of rainfall This ... be used as an indicator of mixing wastewater in water samples when collected under wet weather condition These results indicate the range of variation in the quality of surface runoff which makes ... after the sewerage system, by the streets in downtown Hanoi or due to the malfunctioning and overflowing of the septic systems Although individual households might contribute only minor amounts of...

Ngày tải lên: 05/09/2013, 10:15

... demonstrated by the ratio of the formation rates of the two diol-epoxides, DE2 and DE1 These differ only in the conformation of the 9,10-epoxy-group, anti in DE2 and syn in DE1 The respective data in Fig ... reduction by reductase were measured using an extinction coefficient of 21 mM)1Æcm)1 [27] Lipid was quantitated by measuring the 14C-radioactivity of the fractions by liquid scintillation counting using ... alterations in the metabolite profile, i.e they not alter the stereoselectivity of epoxidation Obviously, there is no alteration of the active site conformation of P450 But the striking parallelism of the...

Ngày tải lên: 08/03/2014, 10:20

... regulating the cGMP affinity of the PDE11A4 tandem GAF domain and thus allosterically affect PDE11 activity The role of the N-terminus of the PDE11A4 GAF tandem domain The N-termini that precede the ... [25,26] In agreement with the expression of PDE5 and PDE11 in the transitional zone of the prostate, these PDE isoforms might also have a role in regulating the proliferation of glandular epithelial ... because of the low cGMP affinity of the PDE11A4 GAF domains [12] Here, we explored whether the PDE11A4 N-terminus is involved in modulating cGMP affinity We generated a panel of nine N-terminally...

Ngày tải lên: 16/03/2014, 06:20

... adiabatic interaction of the electromagnetic wave We insert the expression of nn ,l , p (t ) into the r r expression of j (t ) and then insert the expression of j (t ) into the expression of α in Eq.(4) ... that when the term in proportional to quadratic the intensity of the EMW ( E0 ) (in the expressions of the nonlinear absorption coefficient of a strong EMW) tend toward zero, the nonlinear result ... presents the dependence of the nonlinear absorption coefficient α on the temperature T of the system at different values of the intensity E0 of the external strong electromagnetic wave in the case...

Ngày tải lên: 22/03/2014, 11:20

... Analysis of the reactivity of the K5 peptide with casein in the presence of TGases The time-dependent incorporation of biotinylated peptides (pepK5, pepK5QN and pepT26) into casein was examined in the ... cross-linking of keratinocyte proteins into organized protein structures lead to the formation of the CE Although the cooperative action of several TGases in the keratinocytes plays a role in this ... pepK5QN was not incorporated into casein, also acting as glutamine-donor substrate, in the presence of either TGase or TGase This result indicates that the lysine residue in the sequence of K5 does...

Ngày tải lên: 23/03/2014, 06:20

... not affect binding of DDEL-containing ligands in vitro and in vivo, which suggests that different retrieval signals make different contacts in the binding pocket The variability in the retrieval ... intracellularly retained pFGE was two-fold higher than that of pFGE-His6 Thus, the C-terminal His6-tag impaired retention of pFGE, indicating that the C-terminus of pFGE might be involved in the ER retention ... (basic-X-acidic-leucine) at the C-terminus, with the basic residue being lysine (21 species), arginine (nine) or histidine (four), and the acidic 1120 residue being glutamate (30) or aspartate (four) Murine...

Ngày tải lên: 23/03/2014, 07:20

... pH dependence of the Ep of sulfonephthaleins, and, if any, whether it proceeded in the same direction as the pH dependence of the sulfonephthalein mediators in Table By increasing the pH (from ... without being rapidly metabolized by the enzyme (undesired routes) In this study, we first investigated the kinetics of oxidation of phenol red by Poliporus pinsitus laccase in the absence of any ... charge of the anion onto the adjacent quinoid ring (see Fig 2) Analogously, delocalization of the unpaired electron of the corresponding phenoxy radical onto the quinoid ring would enhance the survival...

Ngày tải lên: 23/03/2014, 21:20

... reproduced in in vitro conditions if nNOS digestion by calpain is carried out in the presence of HSP90 [27] This finding can also explain the large extent of digestion of eNOS in aorta, in which, in association ... previously to induce an increase in the level of [Ca2+]i and a correlated calpain activation [28] This increase in [Ca2+]i is more intense in aorta than in brain Under these conditions, in brain, no ... evidence in support of calpain activation in aorta was provided by the degradation of talin and desmin in HSD-treated rats (Fig 3A) Indeed, this process was completely prevented (Fig 3B) by the administration...

Ngày tải lên: 30/03/2014, 04:20

... glycoprotein consisting of 75-kDa subunits by SDS ⁄ PAGE, partly because of the scarcity of the protein of interest In this study therefore we isolated the antibacterial protein, SSAP, from the skin ... superfamily lectins via its sialylated glycan moiety results in the production of locally high concentrations of H2O2 in or near the binding interface The role of the glycosyl substituents of LAOs in biological ... the mediator of the activity of SSAP 130 Discussion This study is the first to discover an LAO with antibacterial activity in the skin mucus of a teleost and to reveal the involvement of LAO in...

Ngày tải lên: 30/03/2014, 10:20

... significant increase in the content of p28 in the sperm nucleus, possibly through the acrosome reaction-induced activation of nuclear transglutaminase by an increase in the intracellular concentration of ... collected The purity of each histone in the fractions was confirmed by SDS/PAGE The protein concentration was determined by the method of Lowry et al [20] using BSA as the standard In the case of histones ... for gamete fusion The initiation of the acrosome reaction is brought about by an abrupt increase in Ca2+ uptake, which is induced by molecules contained in the jelly coat of the egg [15] Amano...

Ngày tải lên: 31/03/2014, 07:20

... epitopes in the N-terminal (ATPase) domain while the remaining four mAbs, obtained with intact MalK, bind to the C-terminal (regulatory) domain For precise determination of the epitopes overlapping ... recognized by 2F9 are located on the same site but at the bottom part of the C-terminal domain The only moderate effect of MalT on binding of 2F9 argues against these residues being part of the MalT–MalK ... discussed by Bohm et al [14], the ¨ residues may be involved in the signalling pathway that upon binding of enzyme IIAGlc results in the inhibition of ATP hydrolysis Our finding that binding of mAb...

Ngày tải lên: 31/03/2014, 09:20

... softening depends on the melting of these crystallites, but can be changed by a chemical crosslinked network [5] The crosslinking influences on the softening point (Ts) of the PVC samples in comparing ... in the presence of phr of TMPTMA of the PVC crosslinked samples decreases with increasing concentration of TMPTMA up to 15 phr Therefore, in order to obtain PVC having the highest , 0.4 phr of ... improves the molecular mobility, melting and softening of PVC and a result, Ts decreases with increasing Table 1: Softening point of the PVC samples containing different concentrations of DAPC...

Ngày tải lên: 03/04/2014, 15:20

... it into a finite sample of data points by taking a random sample of values of the given mathematical expression in a specified interval of the independent variable We then pair each value of the ... numerically integrating the unknown curve That is, we determine the area under the unknown curve from the beginning of the interval to each of the values of the independent variable The mathematical expression ... genome) by stringing together the four bits from the last two columns in each of the eight rows We can designate the initial state by appending two additional bits (i.e., 00) to the beginning of the...

Ngày tải lên: 08/04/2014, 12:45