... Fatnily and Friends and kicked the ball carefully but I didn't score a goaL Then the ball bounced next to my friend Billy, and he kicked it He scored a goal! Our team scored three goals andthe other ... went to thedinosaurmuseumand learnt how dinosaurs lived It was great! I bought some postcards, a badge, and a model dinosaur in themuseum shop Todayfor lunch I'm having a bowl of pasta and a ... Last night o 0 b The audience listened to the music a Amy and Tom enjoyed the concert b Amy and Tom pLayed their fLutes a The audience clapped and cheered Match the questions and answers Where...
... regulation by the miR-192 ⁄ 1 94 cluster, indicating the direct suppression of Per1, and by these miRNAs (Fig 3B–D) Together, these data indicate that the miR-192 ⁄ 1 94 cluster is a potent and direct ... 1 94 observed in human colorectal cell lines (Fig 5B) FEBS Journal 276 (2009) 544 7– 545 5 ª 2009 The Authors Journal compilation ª 2009 FEBS 544 9 Regulation of the circadian clock by miR-192 ⁄ 1 94 ... capacities towards the 3¢UTRs of all the Per family members (Per1, Per2 and Per3), we identified an miRNA cluster containing miR-192 and miR-1 94 (miR-192 ⁄ 1 94) as powerful regulators The strong expression...
... H Shimano Physiology and pathophysiology of the SREBP family SREBP-1c and lipogenesis The SREBP family consists of three isoforms: SREBP1a, SREBP-1c, and SREBP-2 Each isoform has a ... Physiology and pathophysiology of the SREBP family H Shimano at G1 [19] In particular, p21 is a direct target of SREBP [20] The role of SREBP-1a in the regulation of cell growth andthe cell cycle ... NADPH oxidase and, thus, transforming growth factor-b [40 43 ] Adipogenesis and SREBP-1c SREBP-1c is also known as ADD1, which has been cloned as a regulator of adipogenesis [44 ] The roles of SREBP-1c...
... reflect the ancestry of both rBATs and 4F2hc proteins anchored within the GH13 a-amylase familyThe difference is only in the way leading from the GH13 enzymes either to rBAT and 4F2hc together ... succeeding the b4-strand (not shown) The human 4F2hc thus possesses a very short loop connecting the b4-strand to a4-helix in an opposite manner to what is seen in both the Geobacillus a-glucosidase and ... connecting the b3-strand and helix 3), b4, b5, b7 and b8 represent the individual CSRs of the a-amylase family [13] The positions corresponding with the GH13 catalytic triad are boxed The individual...
... and -D, structure and function L J Reigstad et al endothelial growth factors (VEGF) andthefamily is therefore often referred to as the PDGF ⁄ VEGF familyThe PDGF family of growth factors The ... protease-2 EMBO J 22, 2 348 –2359 36 Romero A, Romao MJ, Varela PF, Kolln I, Dias JM, Carvalho AL, Sanz L, Topfer-Petersen E & Calvete JJ 5738 37 38 39 40 41 42 43 44 45 46 47 (1997) The crystal structures ... of the proposed PDGF-C model [57] displaying the twisted b-sheets andthe N-terminal a-helix of the PDGF-C monomer (A) andthe PDGF-CC dimer (B) The N-terminal (N) and C-terminal (C) ends for the...
... Val 141 , Pro1 54, Ile156 and Pro161 of the other monomer Similarly, Gly175Ala181 forms an anti-parallel intermolecular b sheet with the b12 of the other monomer, and towards the C-terminus, the ... avoredoxin, the twofold axis associated with the dimer passes through the vicinity of the side chains of Pro13, Ile126, Gln133 and Ile163 The corresponding FEBS Journal 276 (2009) 48 4 048 53 ê 2009 The ... at the BL41XU beamline and on a DIP2 040 image-plate detector at the BL44XU beamline (SPring-8, Hyogo, Japan) Data processing, scaling, and reduction were performed using the HKL-2000 system [ 34] ...