development of the embryo and fetus from fertilization until birth

Ngày tải lên: 05/09/2013, 08:40

Ngày tải lên: 22/06/2014, 06:20

Ngày tải lên: 05/09/2013, 09:38

... the superimpo- sition of ApeSOD with the cambialistic SOD from P. shermanii. The overall structures of these enzymes were similar; the rmsd of the 747 Ca atoms was 0.695 A ˚ . ApeSOD eluted from ... with six ligands. The additional water occupied the postulated superoxide bind- ing site. The thermal stability of the enzyme was compared with superoxide dismutase from Thermus thermophilus, a thermophilic ... metal-binding site at the interface of the two domains, which consists of four side chains: two (His31 and His79) from the N-terminal domain and two (Asp165 and His169) from the C-terminal domain...

Ngày tải lên: 14/02/2014, 22:20

... 'all the present of earth vanished into the future of Heaven, and the Kingdom of the Infinite arose upon the ruins of the finite.' The beauty of earth was looked upon as an enchantment of the ... became the nursery, in later times, of landscape, animal, and genre painting. CHAPTER III THE NAIVE FEELING AT THE TIME OF THE CRUSADES In the development and maturing of the race, as of the individual, ... 24 'Let the heavens rejoice and let the earth be glad; let the sea roar, and the fulness thereof. 'Let the field be joyful, and all that is therein; then shall all the trees of the wood...

Ngày tải lên: 21/02/2014, 20:20

... 6E). From these results it can be concluded that tRNAs were bound in classical states with the tRNA Met f bound in the P-sites of the 30S and 50S subunits and the tRNA Phe bound in the A-site of the ... trans- ferase that synthesizes (p)ppGpp. Production of this alarmone results in a down-regulation of stable RNA synthesis (rRNA and tRNA) and up-regulation of the synthesis of mRNAs encoding enzymes ... encoded by the relA locus in Escherichia coli. We have cloned and purified SF from E. coli and examined the ribosome, tem- plate and tRNA-dependence of the pppGpp synthesis reaction. Purification of recombinant...

Ngày tải lên: 07/03/2014, 16:20

... Aedes aegypti [34], and lepidopterans, the tobacco hornworm Manduca sexta [35–37] and the silkworm Bombyx mori [38,39]. On the other hand, the natural ligand of USP is unknown, although recent in ... affinity of DBHs to receptors among insect species is due to the difference of structures of the ligand binding pocket. In the other study, we demonstrated that the molting hormone activities of ecdysone ... decemlineata, EcR and USP, and (c) the measurement of the binding affinity of steroidal and nonsteroidal ecdysone agonists to the in vitro translated receptor proteins. Comparison of the receptor-binding...

Ngày tải lên: 07/03/2014, 21:20

... Land Clearing And Conflicts The agro-industry is another major acquirer and converter of land outside the control of local farmers. Up to the end of the eighties smallholder land acquisition ... continuum of land-use between the forest and the mono-crop plantation. Thus the rigid dichotomy often presumed between forest and plantation is irrelevant to the understanding and management of such ... PROVINCE 9 The Origins Of Present Land-Use: From Ladang To Jungle Rubber 9 Ladang with slash -and- burn 9 The introduction of rubber 9 The making of an agroforestry system 10 From New Planting...

Ngày tải lên: 08/03/2014, 10:20

... L3 2/10 =.2 4/10 =.4 7/10 =.7 10/10 FULL LEAF L1 L1 L1 L2 L2 L2 at their bases, so the oldest parts of a leaf are the tip of the blade and the top of the sheath. Where the blade and sheath join, there are structures called the ligule and the auricles ... evolves as the integration of many consecutive and interacting processes. THE WHEAT BOOK CHAPTER 2 – THE STRUCTURE AND DEVELOPMENT OF THE CEREAL PLANT 25 THE STRUCTURE AND DEVELOPMENT OF THE CEREAL ... uptake into the plant is occurring, and is greater away from the plant roots. Because there is more of the element away from the root, most of the elements will move to the root. Therefore, the net...

Ngày tải lên: 08/03/2014, 23:20

... system, and necessitate the creation of a new honor culture that transcended all classes. The Rise of the Middle Class and the Expansion of Honor At the beginning of the 19 th century, the Industrial ... o improve their own. From the medieval period, they drew from the ideals of chivalry (or at least the folklore of chivalry that had been passed down). From Ancient Greece, they adopt ed parts of Stoic everything ... Part II — The Decline of Traditonal Honor in the West, Ancient Greece to the Romantic Period The most important change of the 19 th century, however, was the rise of the middle class. The Industrial...

Ngày tải lên: 14/03/2014, 09:31

... analysis of costs alone and of costs and benefits, but we omit this step from the diagram because we do not conduct uncertainty analyses on the CGE modeling. The Benefits and Costs of the Clean ... 1-8 and other sector-specific emissions models developed and used in various offices of EPA's Office of Air and Radiation. These emissions models provide estimates of emissions of five ... of the results of quantitative sensitivity tests of key data and assumptions. OVERVIEW OF APPROACH The scope of this analysis is to estimate the incremental direct costs for all criteria and...

Ngày tải lên: 15/03/2014, 16:20

... structures i s the lack of a subdomain formed by two b sheets and one a helix connecting the bsheet 2 of the b subunit, which carries the catalytic glutamate, with the inner l ayer of a helices ... excised from the vector and the inserts were sequenced using standard laboratory protocols. The sequence data w ere analysed using the EXPASY (Expert Protein Analysis System) server of the Swiss ... 553 Da and a n isoelectric point of 4.9 1 was predicted for the encoded p rotein. B oth values w ere in agreement with the observed molecular mass and the elution of the enzyme during the ®nal...

Ngày tải lên: 17/03/2014, 17:20

... with a change in the hydrophobicity of the local environment of Tyr63 and/ or a contribution of the binding of the copper to the thiolates of the protein. A plot of the intensity of the signal at ... developed from standards of known molecular mass and size. Thus, the estimated mass of a given particle is subjected to error if it deviates from the shape and solvation of the molecules used as standards (globular ... Among these is the metal-loaded form of the chaperone in vivo which is a key element to further understanding the mechanism of the metal transfer from a metallochaperone to its target protein. Another...

Ngày tải lên: 23/03/2014, 12:20

... will coincide within the limits of experimental accuracy and therefore the heat-capacity change on unfolding will be the same for the wild-type and the mutant protein. The quality of the multiple-curve ... stability of Thermotoga maritima HU (Eur. J. Biochem. 271) 1501 Thermodynamic analysis of the unfolding and stability of the dimeric DNA-binding protein HU from the hyperthermophilic eubacterium Thermotoga ... a complete understanding of the thermal adaptation strategies of these proteins it is necessary to obtain and compare the unfolding thermodynamic functions of mutants and other family members. HU...

Ngày tải lên: 23/03/2014, 12:20

... construct the SIB1 FKBP22 variants containing either one of these domains and compare their activities and stabilities with those of the intact protein. In this report, the N- and C-domains of SIB1 FKBP22 ... proteolysis of L. pneumophila MIP allows the separation of their N- and C-domains such that the C-domain contains the C-terminal half of the a3 helix [23,24]. In addition, the C-domain of E. coli FkpA ... representations of the pri- mary structures of SIB1 FKBP22* and its variants. A His-tag attached to the N-termini of the proteins is represented by shaded box. The a-helices and b-strands are repre- sented...

Ngày tải lên: 23/03/2014, 13:20

... Using the standard curve constructed from the protein standards (Fig. 4B), the molecular mass of the Peak 1 GST subunit was determined to be 34.0 kDa (Table 2). Peak 2 showed 2 subunits of 36.8 and 32.6 ... profound when the purified enzymes were examined; the specific activities of purified Peak 1 and 2 GSTs from anoxic liver were only 38 and 11%, respectively, of the corres- ponding values for the ... [21]. The hallmarks of anoxia tolerance in turtles include a profound lowering of metabolic rate and a buffering of lactic acidosis [22]. The magnitude of metabolic depression can be 10–20% of the...

Ngày tải lên: 23/03/2014, 15:20

... to other proteins of this class, such as the DNA-binding domain of the Mu repressor [21]. Third, the backbone atoms of the region comprising the ÔwingÕ b-sheet (residues 2–4, 35–36 and 41–44 of ... the N-terminal, structured part of Xis is involved in the recognition of DNA [18,57]. On the other hand, the results also indicate that the C-terminal a-helix, predicted in the work of Wu and co-authors for ... between b-strands 3 and 4. The b-strands 2 (residues Ile30–Phe31) and 5 (residues Val48–Lys49) form the second b-sheet. The Fig. 4. Identification of the IsoAsp66–Gly67 connectivity. (A) The deamidation of...

Ngày tải lên: 23/03/2014, 15:21

... surmise from these findings about the signals regulated by Itk downstream of the TCR dur- ing the development of these various subsets of T cells? Based on the studies to date, it is clear that the ... [20]. In the absence of Itk, there are reduced numbers of iNKT cells in the thymus and periphery [21]. More detailed analysis of the development of Itk-null i NKT cells revealed that they upregulate ... role of Itk in T-cell development. In the absence of Itk, there is a partial block in the development of ab T cells and a reduced ratio of CD4 to CD8 single positive thy- mocytes in both the thymus...

Ngày tải lên: 28/03/2014, 22:21

Ngày tải lên: 29/03/2014, 03:20

Ngày tải lên: 31/03/2014, 01:20