detection of cocaine and its metabolites in breast milk
Hydraulic modeling of open channel flows over an arbitrary 3-d surface and its applications in amenity hydraulic engineering
... depth-averaged model in a nonorthogonal curvilinear coordinates for prediction of flow pattern in meandering channel with 60o and 90o bend, and also with compound meandering channel. In this study, ... concept of simple Rankine vortex that including two parts: free vortex in outer zone and forced vortex in inner zone (Townson 1991)………………………………………33 Figure 4.5 Definition of coordinate components……………………………….36 ... water surface profile into vertical intake. In this regard, the model showed its applicability in computing the flow into intake with air-entrainment. The model was also applied to investigate...
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Expansion and its realization in the short story “the law of life” by jack london
... beginning of the story, the main character was introduced “an old Indian named Koskoosh” and the story is told from the point of view of this character. In the text, one can find many types of ... determine the experiential meaning, interpersonal meaning and textual meaning, respectively. In order to understand a text, apart from its register, it is necessary to understand the genre of ... would like to analyze a randomly chosen text in terms of expansion to see how the findings can help to understand some features of the text and the intention of the writer. In this thesis, the text...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... full-lengthv-KIND; DKIND1, deletion of KIND1;DKIND2, deletion of KIND2; DKIND1 + 2,deletion of both KIND1 and KIND2; DRasN,deletion of RasN; DGEF, deletion of RasGEF; KIND1, KIND1 domain; KIND2,KIND2 ... v-KIND KIND2 binding resides withinresidues 702–744 of MAP2.Residues 456–487 in the KIND2 domain of v-KINDcontain the core MAP2 binding moduleTo identify the core MAP2-binding site within ... sequence for v-KIND binding.To evaluate the v-KIND KIND2-binding specificity of residues 702–744 of MAP2, we performed a pull-down assay of combinations of EGFP-fused KIND1or KIND2 of v-KIND with...
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Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx
... line), in the presence of 100 lM neurotoxin (•, dotted line), in thepresence of 200 lM neurotoxin ( , dottedline) and in the presence of neurotoxin and 50 lM dopamine (h, dashed line).Modulation ... occur in the brain includeselective loss of dopaminergic neurons in substantianigra pars compacta and appearance of Lewy bodiesconsisting of aggregated protein, mainly a-synuclein, in Keywordsamyloid; ... pooled and the amount of protein was determined by the bicinchoninicacid assay [38] using bovine serum albumin as a standardprotein. The pooled eluate fractions were dialysed againstwater and...
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Tài liệu Báo cáo khoa học: A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion docx
... levelincreased in OccWT-overexpressing cells, and that2-APB inhibited the effects of OccWT. Therefore,the increase in intracellular calcium may explain theinduction of apoptosis and reduction ... additionaloccludin variant deleted in exon 9 (OccDE9). On thebasis of a comparative analysis of the involvement of wild-type occludin (OccWT) and variant occludin in apoptosis and invasion, as determined ... as one of themechanisms of this regulation. On the basis of theabove findings, our research provides new insights intothe role of exon 9 in the regulation of apoptosis and invasion in liver...
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Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx
... obtained from injections of the metal into a solution of the protein. Typically an initial injection of 2 lL copperchelate solution was followed by a further 29 injections of 4 lL of Cu(II) into ... stage of tetramerization. Possibly, loss of copper binding could still allow domain swapping tooccur. It is of interest that a N-terminally truncated pri-on protein, lacking the copper binding ... Ratiokcal/mole of injectantkcal/mole of injectantkcal/mole of injectantkcal/mole of injectantkcal/mole of injectantkcal/mole of injectant-20-1-0.5 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0Stefin...
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Tài liệu Báo cáo khoa học: Biochemical characterization of human 3-methylglutaconyl-CoA hydratase and its role in leucine metabolism docx
... usingcrotonyl-CoA as a substrate [15]. The gene encodingthis bifunctional protein was named AUH (‘AU bind-ing homolog of enoyl-CoA hydratase’). The RNA-binding activity of the human protein ... mutations in the AUH gene. This indi-cated that AUH, in addition to its RNA binding func-tion, must play an important role in leucine catabolism.AUH was overproduced in E. coli and characterizedby ... inclu-ding equilibration, was 10 min. A splitter between theHPLC column and the mass spectrometer was used, and 100 lLÆmin)1 of eluent was introduced into the mass spec-trometer. A LCT TOF...
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Tài liệu Báo cáo khoa học: Inhibitory properties of cystatin F and its localization in U937 promonocyte cells ppt
... processregulating its inhibitory properties.Screening of proteases for their inhibition showedthat cystatin F is different from other cystatins, both in terms of specificity and strength of binding to ... Cystatins are generally rather non-selective inhibitors. An interesting feature of cystatinF is the 100-fold stronger inhibition of cathepsins F,L, and V than of cathepsin S. Cathepsin S is ... cystatin C is the mostdiscriminating residue for binding to cathepsins B, H,L, S [24]. No L9K mutants of cystatin C have beenprepared yet to study the effect of incorporating theCystatin F in...
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Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
... concerning the kinetics and properties of theenzyme. More strikingly, we show a novel role of the PPaseenzyme in the development and molting process of A. suumlarvae in vitro.Materials and methodsParasitesAdult ... Vmax(maximum velocity)values were determined by incubating the diluted recombin-ant proteins in the standard reaction mixture in the presence of increasing concentrations of PPi(0.05–0.5 mM)at55°C.Data ... Diluted recombinant proteins were run in thestandard reaction mixture (as described in Materials and methods) forPPase assays at 55 °C, in the presence of increasing concentrations of PPi(0.05–0.5...
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Báo cáo khoa học: Expression of cholinesterases in human kidney and its variation in renal cell carcinoma types pdf
... erythrocytes in the extent of binding with thelectins concanavalin A, Lens culinaris agglutinin(LCA), and Ricinus communis agglutinin (RCA)(Fig. 3), ruled out the blood origin and supported therenal ... butyrylcholinesterase activityassayed in kidney. This proposal is in agreementwith the cytochemical staining of acetylcholinesterase in the capsule of Bowman [41] and of acetylcholines-terase and ... appreciableincrease in butyrylcholinesterase activity of chRCC,cRCC, and RO, instead of its invariability (Table 1),should have been expected, along with a robustincrease in the proportion of G4Hbutyrylcholinester-ase....
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Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf
... plasmid and a virus. Mol Microbiol 34, 217–226.29 Bradford M (1976) A rapid and sensitive method forthe quantification of microgram quantities of proteinutilizing the principle of protein-dye binding. ... clarified in detail and could playa key role in the detoxification processes. In this study we examined the role of Bcp2 in orderto increase the knowledge of the enzymatic activityinvolved in the ... important in deter-mining the level of Bcp2 protein. Similar results areobserved for genes and related proteins involved in oxidative stress in other microrganisms [24]. Moreover,the basal level of...
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Báo cáo khoa học: Molecular and functional characterization of a novel splice variant of ANKHD1 that lacks the KH domain and its role in cell survival and apoptosis docx
... identified a proteincontaining a single ankyrin repeat that interacts withHIV-1 viral protein R (Vpr) and we designated thisprotein as Vpr-binding ankyrin repeat protein(VBARP). This interaction ... ankyrin repeat motif-containing proteins play an important role in protein–protein interactions. ANKHD1 proteins are known to possessmultiple ankyrin repeat domains and a single KH domain with ... Institute, Shanghai, China.8 Smith RK, Carroll PM, Allard JD & Simon MA (2000)MASK, a large ankyrin repeat and KH domain-con-taining protein involved in Drosophila receptor tyrosinekinase...
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Báo cáo khoa học: "Detection of Agreement and Disagreement in Broadcast Conversations" pot
... train-ing set by either oversampling the minority class ordownsampling the majority class. In this prelimi-nary study of sampling approaches for handling im-balanced data for CRF training, ... using constraint classifiers. In Proceedings of HLT/NAACL.D. Hillard, M. Ostendorf, and E. Shriberg. 2003. De-tection of agreement vs. disagreement in meetings:Training with unlabeled data. In ... genre in thatit is more interactive and spontaneous, referring tofree speech in news-style TV and radio programs and consisting of talk shows, interviews, call -in programs, live reports, and...
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Chemical of alumina reactions in aqueous solution and its application in water treatment
... presence and importance of alumina in thenatural aquatic environment and its growing application in drinking and wastewater purification, the knowledge of alumina’s structure and possible interactions ... structure of alumina and its possible interactions with organic and inorganiccompounds in water are of great importance. This is of particular importance in both the understanding of natural ... Poland´{AbstractDue to the presence and significance of alumina in the natural aquatic environment and its increasing application in drinking and wastewater purification, the knowledge of...
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Báo cáo khoa học: Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer’s disease brain doc
... FEBSLevels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer’sdisease brainXu Li1, Irina Alafuzoff2, Hilkka Soininen3, Bengt Winblad1 and ... staining in the granulelayers of the dentate gyrus (not shown). In contrast, in control brain slices there was weak stainings in thepyramidal neurons of the CA1, CA2, CA3 and theentorhinal ... proteins witheither polyglutamine or polyalanine expansions in Huntington disease, Huntington related diseases, and various forms of a-synuclein associated with Parkinsondisease and synucleinopathies...
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- a diminished quality of life and an increase in healthcare costs
- cocaine and its metabolites
- and its treatment in a machine translation system s
- detection of agreement and disagreement
- characteristics of obesity and its related disorders in china
- excretion of cocaine and its metabolites in man
- detection of cocaine and its metabolites
- cocaine and its metabolites in urine
- detection of agreement and disagreement in broadcast conversations
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