excretion of cocaine and its metabolites in man
Báo cáo y học: "Management of chest pain: exploring the views and experiences of chiropractors and medical practitioners in a focus group interview"
... chiropracticeducational institution offering a training program coor-dinated by a medical physician. However, this is in its infancy and much needs to be worked out. This does indi-cate a growing level of interest ... relative to enhancingdiagnostic competencies in chest pain, as well as the need to ascertain and improve those skills,competencies, and standards for referrals and sharing of clinical information ... Inter-professional coordination of care; (5) Best practices and standardization of care; and (6) Training and education.Conclusion: This study carries implications for chiropractic clinical training relative...
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Hydraulic modeling of open channel flows over an arbitrary 3-d surface and its applications in amenity hydraulic engineering
... depth-averaged model in a nonorthogonal curvilinear coordinates for prediction of flow pattern in meandering channel with 60o and 90o bend, and also with compound meandering channel. In this study, ... concept of simple Rankine vortex that including two parts: free vortex in outer zone and forced vortex in inner zone (Townson 1991)………………………………………33 Figure 4.5 Definition of coordinate components……………………………….36 ... water surface profile into vertical intake. In this regard, the model showed its applicability in computing the flow into intake with air-entrainment. The model was also applied to investigate...
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Expansion and its realization in the short story “the law of life” by jack london
... beginning of the story, the main character was introduced “an old Indian named Koskoosh” and the story is told from the point of view of this character. In the text, one can find many types of ... as in the case of taxposition. Dozens of people were stranded, many of them being children. (additive) (Quirk and Greenbaum, 1987: 312) 2.3.3. Enhancement In enhancement, the meaning of ... determine the experiential meaning, interpersonal meaning and textual meaning, respectively. In order to understand a text, apart from its register, it is necessary to understand the genre of...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... full-lengthv-KIND; DKIND1, deletion of KIND1;DKIND2, deletion of KIND2; DKIND1 + 2,deletion of both KIND1 and KIND2; DRasN,deletion of RasN; DGEF, deletion of RasGEF; KIND1, KIND1 domain; KIND2,KIND2 ... v-KIND KIND2 binding resides withinresidues 702–744 of MAP2.Residues 456–487 in the KIND2 domain of v-KINDcontain the core MAP2 binding moduleTo identify the core MAP2-binding site within ... sequence for v-KIND binding.To evaluate the v-KIND KIND2-binding specificity of residues 702–744 of MAP2, we performed a pull-down assay of combinations of EGFP-fused KIND1or KIND2 of v-KIND with...
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Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx
... line), in the presence of 100 lM neurotoxin (•, dotted line), in thepresence of 200 lM neurotoxin ( , dottedline) and in the presence of neurotoxin and 50 lM dopamine (h, dashed line).Modulation ... occur in the brain includeselective loss of dopaminergic neurons in substantianigra pars compacta and appearance of Lewy bodiesconsisting of aggregated protein, mainly a-synuclein, in Keywordsamyloid; ... pooled and the amount of protein was determined by the bicinchoninicacid assay [38] using bovine serum albumin as a standardprotein. The pooled eluate fractions were dialysed againstwater and...
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Tài liệu Báo cáo khoa học: A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion docx
... levelincreased in OccWT-overexpressing cells, and that2-APB inhibited the effects of OccWT. Therefore,the increase in intracellular calcium may explain theinduction of apoptosis and reduction ... additionaloccludin variant deleted in exon 9 (OccDE9). On thebasis of a comparative analysis of the involvement of wild-type occludin (OccWT) and variant occludin in apoptosis and invasion, as determined ... regions of exon 8 and exon 9 in the genomicDNA of Chang cells were sequenced and aligned with OccWT. (F) Schematic of mRNA coding sequence for human occludin, showing thecomparison of OccWTand...
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Tài liệu Báo cáo khoa học: DNA modification with cisplatin affects sequence-specific DNA binding of p53 and p73 proteins in a target site-dependent manner pptx
... activity of cisplatin. FASEB J 12, 791–799.30 Kasparkova J & Brabec V (1995) Recognition of DNAinterstrand cross-links of cis-diamminedichloroplatinu-m(Ii) and its trans isomer by DNA-binding ... lacking the cisplatin-reactive motifsor containing multiple guanine doublets and ⁄ or triplets(Fig. 7), were used to check the in uence of cisplatinadducts in the vicinity of p53DBS. Again, ... targets).Effects of DNA cis-platination on sequence-specific DNA binding of p73 proteinsWe tested the in uence of DNA modification withcisplatin on the binding of two p73 isoforms, p73d and p73b, to the p21...
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Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx
... obtained from injections of the metal into a solution of the protein. Typically an initial injection of 2 lL copperchelate solution was followed by a further 29 injections of 4 lL of Cu(II) into ... stage of tetramerization. Possibly, loss of copper binding could still allow domain swapping tooccur. It is of interest that a N-terminally truncated pri-on protein, lacking the copper binding ... num-ber of places, but in particular, stefin B has a number of histidines in the C-terminus (box in Fig. 1) at sites:92, 75, 66 and 58. As histidine residues are central tocopper binding in many...
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Tài liệu Báo cáo khoa học: Biochemical characterization of human 3-methylglutaconyl-CoA hydratase and its role in leucine metabolism docx
... usingcrotonyl-CoA as a substrate [15]. The gene encodingthis bifunctional protein was named AUH (‘AU bind-ing homolog of enoyl-CoA hydratase’). The RNA-binding activity of the human protein ... reaction of leucine catabolism at the protein and DNA levels and developed a novel assay forenzyme analysis in a diagnostic setting. The humanAUH protein was first recognized by its ability to bindA ... protein (AUHp40). Westernblot analysis of brain extracts consistently revealed a32 kDa AUH protein and it was thus assumed thatthe mature form of human AUH in brain has amolecular weight of...
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Tài liệu Báo cáo khoa học: Inhibitory properties of cystatin F and its localization in U937 promonocyte cells ppt
... processregulating its inhibitory properties.Screening of proteases for their inhibition showedthat cystatin F is different from other cystatins, both in terms of specificity and strength of binding to ... Production of human sali-vary type cysteine proteinase inhibitors (cystatins) by anEscherichia coli system and partial characterization of recombinant cystatin S and its mutant (117 arginine fitryptophan). ... Buttle DJ,Grubb A & Ohlsson K (1991) Human cystatin C: role of the N-terminal segment in the inhibition of humancysteine proteinases and in its inactivation by leucocyteelastase. Biochem...
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Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
... concerning the kinetics and properties of theenzyme. More strikingly, we show a novel role of the PPaseenzyme in the development and molting process of A. suumlarvae in vitro.Materials and methodsParasitesAdult ... Vmax(maximum velocity)values were determined by incubating the diluted recombin-ant proteins in the standard reaction mixture in the presence of increasing concentrations of PPi(0.05–0.5 mM)at55°C.Data ... increasing concentrations of inhibitors for10 days, and the number of molting larvae was determined.Molting was manifested by shedding of the L3 cuticle.Numbers of molted larvae in a culture well...
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Tài liệu PHYSICAL, CHEMICAL, AND MECHANICAL PROPERTIES OF BAMBOO AND ITS UTILIZATION POTENTIAL FOR FIBERBOARD MANUFACTURING docx
... Properties and utilization of Philippine erect bamboo. In: (G.Lessard and A. Chouinard, eds.). International Seminar on Bamboo Research in Asia. Singapore, May 28-30. Singapore: International ... hemicellulose and lignin in immature bamboo increased while proceeding downward of the culm. The increase of cellulose in the lower position was also accompanied by an increase in crystallinity. The ... W. and G. Weiner. 1997. Modifications of bamboo culm structures due to ageing and wounding. In: (G. Chapman, eds.). The Bamboos. The Linnean Society, London. pp. 313-322. Leithoff, H. and...
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Báo cáo khoa học: Expression of cholinesterases in human kidney and its variation in renal cell carcinoma types pdf
... erythrocytes in the extent of binding with thelectins concanavalin A, Lens culinaris agglutinin(LCA), and Ricinus communis agglutinin (RCA)(Fig. 3), ruled out the blood origin and supported therenal ... butyrylcholinesterase activityassayed in kidney. This proposal is in agreementwith the cytochemical staining of acetylcholinesterase in the capsule of Bowman [41] and of acetylcholines-terase and ... appreciableincrease in butyrylcholinesterase activity of chRCC,cRCC, and RO, instead of its invariability (Table 1),should have been expected, along with a robustincrease in the proportion of G4Hbutyrylcholinester-ase....
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Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf
... plasmid and a virus. Mol Microbiol 34, 217–226.29 Bradford M (1976) A rapid and sensitive method forthe quantification of microgram quantities of proteinutilizing the principle of protein-dye binding. ... clarified in detail and could playa key role in the detoxification processes. In this study we examined the role of Bcp2 in orderto increase the knowledge of the enzymatic activityinvolved in the ... important in deter-mining the level of Bcp2 protein. Similar results areobserved for genes and related proteins involved in oxidative stress in other microrganisms [24]. Moreover,the basal level of...
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Báo cáo khoa học: Molecular and functional characterization of a novel splice variant of ANKHD1 that lacks the KH domain and its role in cell survival and apoptosis docx
... identified a proteincontaining a single ankyrin repeat that interacts withHIV-1 viral protein R (Vpr) and we designated thisprotein as Vpr-binding ankyrin repeat protein(VBARP). This interaction ... ankyrin repeat motif-containing proteins play an important role in protein–protein interactions. ANKHD1 proteins are known to possessmultiple ankyrin repeat domains and a single KH domain with ... ankyrin repeat is a 33-amino acid motif present in repeats of 12–24 and first identified in yeast and Drosophila [1]. Ankyrin-repeat-containing proteinsregulate multiple cellular functions including...
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- a diminished quality of life and an increase in healthcare costs
- cocaine and its metabolites
- and its treatment in a machine translation system s
- list of small and medium enterprises in kenya
- ebusiness and manufacturing sector a study of small and mediumsized enterprises in india
- characteristics of obesity and its related disorders in china
- detection of cocaine and its metabolites in breast milk
- detection of cocaine and its metabolites
- cocaine and its metabolites in urine
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