dds deds cards and pyds assembly of caspase activating signalling complexes
64th Annual Obstetrical and Gynecological Assembly of Southern California docx
Ngày tải lên :
28/03/2014, 14:20
... Department of Obstetrics and Gynecology Cedars-Sinai Medical Center Professor and Vice-Chair, Dept of Obstetrics and Gynecology, and Professor, Dept of Medicine The David Geffen School of Medicine ... PH.D Professor and Chair Department of Obstetrics and Gynecology and Pharmacology David Geffen School of Medicine at UCLA Los Angeles, California Ramen Chmait, M.D Assistant Professor of Obstetrics ... Obstetrics and Gynecology Chief of the Division of Reproductive Endocrinology and Infertility University of Southern California Los Angeles, California Andrea Rapkin, M.D Professor, Department of Obstetrics...
- 9
- 257
- 0
Role of p73 in regulation of cell death specific role in mitotic cell death and potential regulation of caspase 2s
Ngày tải lên :
13/09/2015, 21:21
... expression of p73 not affect the transcript level of any other caspases tested except caspase- 2S The induction of caspase- 2S is unique to p73β and DNp73β but not p73α, p53 or p63 This induction of caspase2 S ... level of Bubr1 and Mad2 after knockdown of p73 105 Fig 3.28: Different mechanism of action between p73 and Bubr1 and Mad2 in regulation of mitotic cell death 107 Fig 3.29: Knockdown of Bubr1 and ... 4.1.3 Transcriptional regulation of Caspase- 2S 4.1.4 Aims 4.2 Caspase- 2S but not caspase- 2L, caspase- 8 and caspase- 9 is up-regulated by p73β 4.3 p73β can induce caspase- 2S promoter reporter construct...
- 238
- 205
- 0
Synthesis, characterization and self assembly of stimuli sensitive materials
Ngày tải lên :
14/09/2015, 14:02
... (A and C) and emission (B and D) spectra of dithienylethenes photochromism in chloroform solution; DTEPh (A and B) and DTE-Naph (C and D) 121 Figure 4.4 Change in the color upon irradiation of ... (diazo) and photochromic (dithiaethylene) moelcuels were discussed The photochromism and self -assembly of the compounds were explored The formation of well defined nanorings and role of concentration ... 2.4 Absorption (A) and emission spectra (B) of copolymers in THF solution; P1 (▲), P2 ( ), P3 ( ), and P4 ( ) 70 Figure 2.5 TEM images of nanofibres formed by self -assembly of copolymers (P2)...
- 232
- 1.2K
- 0
Electrochemical syntheses and self assembly of nanostructure as modified electrodes for polythiophene preparation
Ngày tải lên :
17/09/2015, 17:17
... Bibliography 197 x List of Figures 1.1 Illustration of energy band structures of materials VB: valence band, CB: conduction band 1.2 Polaron and bipolaron structures of polythiophene ... the band theory which explains the electronic structure of materials (Figure 1.1) [14] The highest occupied bands are the valence band (VB) and the lowest unoccupied bands are the conduction band ... ¯rst 10 CV cycles of (a) P3OCBT and (b) P3OMEBT and (c) P3BRBT in monomer free BF3 ¢OEt2 , scan rate: 50 mV s¡1 73 3.3 CV of p-dope of PBRHEBT in monomer free (A) BF3¢OEt2 and (B) 0.1 M Bu4...
- 247
- 400
- 0
153 The role of marketing activities to bankcard and actual state of Ngân hàng nông nghiệp và phát triển nông thôn (AgriBank) cards
Ngày tải lên :
03/04/2013, 12:13
... to divide bankcards Figure - Types of bankcards Cards Payment method Technical Feature Issuer Area of Using card International card Domestic card Travel and Entertainment cards Bankcards Smart ... TO BANKCARD AND ACTUAL STATE OF AGRIBANK CARDS 2.1 Introduction of Vietnam Bank for Agriculture and Rural Development (Agribank) - Thanh Xuan branch 2.1.1 Foundation and development of Agribank ... performance of Services and Marketing Department 4th quarter, 2009 The table shows the total profit from operation of services in Services and Marketing Department in three month and accumulation of 12...
- 33
- 662
- 0
494 The role of marketing activities to bankcard and actual state of Ngân hàng nông nghiệp và phát triển nông thôn (AgriBank) cards
Ngày tải lên :
08/04/2013, 17:01
... tiền phải dựa sở nguời vay phải có khả trả cho người cho vay tương lai Nhu cầu có khả toán(Demands): nhu cầu tự nhiên mong muốn hợp với khả mua sắm Nhà kinh doanh phát nhu cầu tự nhiên, mong ... cấp) thay văn phòng đại diện để trở thành Nhà phân phối thức Tên giao dịch Quốc tế: Equipments and Values Development Tên viết tắt: EVD, Co., Ltd Trụ sở chính: Tầng – Số 10 – Lê Quý Đôn –...
- 66
- 670
- 0
Tài liệu Báo cáo khoa học: Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans pptx
Ngày tải lên :
19/02/2014, 07:20
... studies of the reductive half-reaction of AADH Studies of the reductive half-reaction were performed to allow comparison of kinetic parameters for native and recombinant AADH Reduction of the TTQ cofactor ... orf-4 and hemE) all putatively transcribed in the same direction [7] The second and fifth genes (aauA and aauB) encode the large and small subunits of AADH, respectively The genes aauD and aauE ... analysed and intermediates of the reaction identified by global analysis and numerical integration methods using prokin software (Applied Photophysics) In studies of the temperature dependence of bond...
- 16
- 605
- 0
Tài liệu Báo cáo khóa học: Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b pdf
Ngày tải lên :
19/02/2014, 12:20
... panels A and B and the relative amounts of each of the subunits determined by densitometry scanning of the stained Western blots of the q° and CKL57 membranes are shown in panels C and D, respectively ... strongest defect in the assembly of the catalytic subunits of cytochrome bc1 complex This strain showed only 18% and 6% of the wild-type levels of iron– sulfur protein and cytochrome b, respectively, ... b and ISP were reduced to about 12% and 27% of the original levels Cytochrome c1 and core proteins and decreased by about 50%, whereas a greater decrease was found in the case of subunits 7, and...
- 10
- 517
- 0
Tài liệu Báo cáo khoa học: The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase) pptx
Ngày tải lên :
19/02/2014, 16:20
... expression, and it is still unclear how the level of a complex of 46 subunits is determined The activities of complex II and the downstream complex III of the electron transport chain were measured and ... formation of supercomplexes and the effect of the absence of intact complex I, but the results are too preliminary in this regard Heterologous expression of the ESSS-HA subunit The localization of the ... subunit for assembly of an active mammalian mitochondrial complex I Experimental procedures Cell lines and cell culture The isolation and preliminary biochemical and genetic characterization of a series...
- 9
- 622
- 0
Tài liệu Báo cáo Y học: The RuvABC resolvasome Quantitative analysis of RuvA and RuvC assembly on junction DNA doc
Ngày tải lên :
21/02/2014, 01:21
... derive kinetic and equilibrium constants and also allows Ó FEBS 2002 Assembly of RuvA and RuvC on Holliday junctions (Eur J Biochem 269) 5495 the calculation of the stoichiometry of the interaction ... remove the effects of the bulk refractive index change at the beginning and end of the injections (which occur as a result of a difference in the composition of the running buffer and the injected ... with an overall Kd of approximately 0.2 nM and also demonstrate the formation of a RuvA/C complex on the Holliday junction MATERIALS AND METHODS Synthesis and purification of oligodeoxynucleotides...
- 10
- 672
- 0
Báo cáo khoa học: Assembly and molecular mode of action of the Helicobacter pylori Cag type IV secretion apparatus doc
Ngày tải lên :
06/03/2014, 00:21
... the molecular mechanisms of effector protein secretion This minireview describes the composition of the cagPAI and the properties of both conserved and unique components of the Cag-T4SS, together ... potential implications for the current understanding of its mode of action The cagPAI and the Cag type IV secretion apparatus Gene arrangement and variants of the cagPAI The cagPAI, which was originally ... an inversion of cagQ, a duplication of cagA and cagB associated with cagA degeneration, and a more complex rearrangement comprising all cag genes except cagA and a second inversion of several flanking...
- 10
- 393
- 0
Báo cáo khoa học: Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria doc
Ngày tải lên :
07/03/2014, 00:20
... it represents an important step in assembly of the holoenzyme Results In vitro import and assembly of nDNA-encoded complex IV subunits The assembly of a number of nDNA-encoded complex IV subunits ... involvement of Surf1 in the formation and assembly of the LSI complex BN-PAGE and western blot analysis of mitochondria solubilized in DDM indicated that the fibroblasts of patients and had very ... Lazarou et al complexes in the range of approximately 700–1000 kDa (lanes and 2), but these did not co-migrate with any of the complex IV-containing supercomplexes The identity of these complexes...
- 13
- 314
- 0
Báo cáo khoa học: Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1 – a molecular link between recombination and chromatin assembly during meiosis pot
Ngày tải lên :
07/03/2014, 05:20
... complex of Hop2 and Mnd1 stimulates strand exchange of Lim15/Dmc1 [9–11] The meiosis-specific proteins Mei5 and Sae3 form a complex with Lim15/Dmc1 and are necessary for the assembly of Lim15/Dmc1 ... partners of Lim15/Dmc1, which seem to be involved in homology search and strand exchange Tid1/Rdh54, an SWI2/SNF2 family of chromatin-remodelling factors, promotes the co-localization of Rad51 and ... activity and invades the homologous doublestranded region of the other allele These steps of homology search and recombination are catalysed by two bacterial RecA homologues, Rad51 and Lim15/Dmc1...
- 10
- 487
- 0
Báo cáo khoa học: ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells potx
Ngày tải lên :
16/03/2014, 01:20
... domain of HSP70 is essential for the inhibition of H2O2-induced activation of caspases-9 and -3 and apoptosis (A) The effects of HSP70 and its deletion mutant proteins on the activation of caspases-9 ... role of HSP70 in the inhibition of the release of Smac and apoptosis GAPDH Ratio of HSP70 to GAPDH 14 # 12 # 10 * The role of the ATP-binding domain of HSP70 in the prevention of the release of ... etoposide and glucocorticoids [10,11] Smac promotes caspase activation by eliminating inhibition of caspases by inhibitor of apoptosis protein (IAP) and is known to be a new and important regulator of...
- 10
- 726
- 0
Báo cáo khóa học: Assembly of the silk fibroin elementary unit in endoplasmic reticulum and a role of L-chain for protection of a1,2-mannose residues in N-linked oligosaccharide chains of fibrohexamerin/P25 ppt
Ngày tải lên :
16/03/2014, 16:20
... significance of the assembly of the elementary unit of fibroin in ER It was demonstrated in this study that the elementary unit of fibroin, having the same molar ratio of H- and L-chains, and fhx/P25 as of ... as two bands of 30 and 27 kDa (Fig 5C, lanes 3, and 4, 8) like in the normal breed C108 (Fig 5C, lanes and 5) The slight decrease in electrophoretic mobility of fhx/P25 after cleavage of disulfide ... H-chain gene, fibH [9] Nd-s and Nd-sD are mutations of the fibroin L-chain gene, fibL [8,10] Preparation of fibroin and purification of fhx/P25 Fibroin samples from PSG lumen and cocoons were prepared...
- 11
- 552
- 0
Báo cáo khoa học: Natural and amyloid self-assembly of S100 proteins: structural basis of functional diversity doc
Ngày tải lên :
23/03/2014, 03:20
... the EF-hands in S100 proteins Structure of the N-terminal, S100-specific EF-hand (A) and the C-terminal, canonical EF-hand (B) in the metal-free (lighter) and Ca2+-bound (darker) form of S100A6 ... deposition and tissue remodelling [14] The conversion of functional proteins and peptides into insoluble amyloid structures and their deposition in a variety of tissues and organs is a hallmark of a ... hetero-oligomeric complexes of S100A8 ⁄ A9 are characterized by significant stability and protease resistance comparable with that of prions In the protease-rich environment of the prostate gland, and especially...
- 13
- 584
- 0
Báo cáo Y học: Requirement of caspase and p38MAPK activation in zinc-induced apoptosis in human leukemia HL-60 cells potx
Ngày tải lên :
23/03/2014, 21:20
... execution of apoptosis [26] We therefore examined the involvement of caspases in the apoptosis induced by Py/Zn PARP is a substrate of caspases, and proteolysis of PARP is an index of activation of caspases ... on the inhibition of activation of caspases, and also as an inducer of apoptosis, dependent on the activation of caspases [23,65] However, the mode of action of Zn in induction of apoptosis remains ... changes in the time courses of induction of apoptosis (Fig 3A) and proteolysis of PARP (Fig 3B) by Py/Zn Induction of apoptosis and activation of caspases were observed at h of treatment Moreover,...
- 8
- 439
- 0
Báo cáo khóa học: Protein assembly of photosystem II and accumulation of subcomplexes in the absence of low molecular mass subunits PsbL and PsbJ pdf
Ngày tải lên :
30/03/2014, 13:20
... disassembly and assembly of PSII is constantly occurring because of turnover of the reaction center D1 protein [30] In particular, the role of PsbL and PsbJ in the assembly and stability of PSII ... in the absence of any assembly of PSII, as was evident for the DpsbE and DpsbF tobacco mutants (Fig 1B) Thus, to understand the role of various LMM subunits in the stable assembly of PSII, it is ... analysis of the thylakoid protein complexes from mature leaves of wild-type and DpsbF, DpsbL and DpsbJ mutants of tobacco Thylakoids were solubilized and subjected to BN-PAGE separation of the...
- 12
- 401
- 0
Báo cáo khoa học: Assembly of collagen types II, IX and XI into nascent hetero-fibrils by a rat chondrocyte cell line ppt
Ngày tải lên :
31/03/2014, 07:20
... polymeric type II N-procollagen and if types IX and XI collagens were also incorporated, in order to understand better the temporal sequence and mechanism of assembly Materials and methods Cell culture ... chains and chain fragments of types II, IX and XI collagen were resolved by SDS/ PAGE (Fig 7A, lanes and 5) Western blot analysis (Fig 7A, lanes and 2) of the proteins resolved in lanes and using ... synthesis and secretion of proteins The extracellular matrix, however, featured extensive electron-lucent areas and a distinctive lack of Ó FEBS 2003 Cartilage collagen heteropolymer assembly...
- 8
- 376
- 0
Báo cáo hóa học: " Rift Valley fever virus structural proteins: expression, characterization and assembly of recombinant proteins" potx
Ngày tải lên :
20/06/2014, 01:20
... complex and assembled into a particulate structure in the absence of genomic RNA Figure Assembly of VLPs by expression of RVFV N and Gc proteins Assembly of VLPs by expression of RVFV N and Gc ... purification of proteins and VLPs, and EM studies CC carried out cell surface expression and cell to cell fusion studies PR contributed in the coordination and design of the study and helped in ... Morikawa S, Bishop DH: Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian Sandfly fever, and Uukuniemi viruses Virology...
- 13
- 337
- 0