covalent polycyclic aromatic hydrocarbon dna adducts carcinogenicity structure and function
báo cáo khoa học: " Transcriptional responses to polycyclic aromatic hydrocarbon-induced stress in Arabidopsis thaliana reveal the involvement of hormone and defense signaling pathways" pdf
Ngày tải lên :
12/08/2014, 03:21
... higher plants exposed to polycyclic aromatic hydrocarbons and their N-heterocyclic derivatives Environ Toxicol Chem 2006, 25:3238-3245 Burritt DJ: The polycyclic aromatic hydrocarbon phenanthrene ... invertebrate Folsomia candida exposed to phenanthrene BMC Genomics 2009, 10:236 45 Baird WM, Hooven LA, Mahadevan B: Carcinogenic polycyclic aromatic hydrocarbon- DNA adducts and mechanism of action ... ⎟ ⎝ ⎠ ⎝ ⎠ δc and δp are standard deviations of organ length in control and phenanthrene treatment, respectively; nc and np are numbers of roots or hypocotyls measured in control and phenanthrene...
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determination of polycyclic aromatic hydrocarbon pahs and aliphatic hydrocarbons in oysters by gc msms
Ngày tải lên :
09/09/2015, 09:38
... of aliphatic hydrocarbon standards (NIST1494 – C10-C34 hydrocarbons) and secondly a mixture of 16 PAH standards To evaluate method performance with combined aliphatic hydrocarbons and PAHs, spiking ... standard solution Rf = ASt × c[IS] A[IS] × cSt Rf – the response factor determined by the analysis of standards PAH and internal standard ASt – the area of the PAH peak in the calibration standard ... NIST1494 hydrocarbon standard Legal Notices ©2010 Thermo Fisher Scientific Inc All rights reserved Standard Reference Material is a registered trademark of NIST (National Institute of Standards and...
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Báo cáo y học: "A comparative approach for the investigation of biological information processing: An examination of the structure and function of computer hard drives and DNA" doc
Ngày tải lên :
13/08/2014, 16:20
... comparative analysis between the architecture and function of the CHD and the structure and function of eukaryotic DNA, which we now define as the DNA hard drive (DHD) The computer ATA (Advanced ... system for identifying and Figure Organized cluster mapping of DNA to Nucleus Mapping of DNA strand into DNA Hard Drive: A) shows the DNA strand decomposed into its information structure The top layer ... infrastructure (RNA and proteins) The structure and function of this information-processing complex are of great interest in the study of both normal cellular functions (such as differentiation and...
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Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf
Ngày tải lên :
14/02/2014, 18:20
... tails and DNA, ren- Active chromatin and DNase I hypersensitive sites dering individual nucleosomes more unstable and mobile These histone tail contacts occur primarily with the linker DNA rather ... core of 60 bp of DNA, followed by the loading of two H2A ⁄ H2B dimers onto the flanking DNA segments above and below the H3 ⁄ H4 tetramer Throughout the nucleosome, each DNA strand of the helix ... Active chromatin and DNase I hypersensitive sites A Anatomy of the inducible DNaseI hypersensitive site in the GM-CSF enhancer in T cells 140 Nucleosome N1 Nucleosome N2 DNase I and MNase NFAT...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
Ngày tải lên :
14/02/2014, 19:20
... MAP2 cDNA and its derivatives generated by PCR were cloned into pGEX-4T-2 The KIND domains of Spir-2 and PTPN13 were generated by RT-PCR and inserted into pEGFP-C1 and pGEX-4T-2 The N- and C-terminal ... clarified the structural and functional importance of the v-KIND and MAP2 interaction core modules in the regulation of dendrite growth and branching in hippocampal neurons and cerebellar granule ... polymerization, stability and rearrangement of microtubules in neuronal dendrites [13–15] and is associated with some neurological and psychiatric disorders [16,17] However, the structure function relationship...
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Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx
Ngày tải lên :
17/02/2014, 19:20
... marine and freshwater ecosystems James H Brown, Andrew P Allen and James F Gillooly Body size and suspension feeding Stuart Humphries 16 Life histories and body size 10 David Atkinson and Andrew ... empirical and theoretical work in biological oceanography and limnology that relates the structure, function and biotic composition of these systems to the body sizes of the organisms present and the ... important, and (ii) to compare freshwater and marine ecosystems In Body Size: The Structure and Function of Aquatic Ecosystems, both those questions of scale and comparison among systems are very...
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Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx
Ngày tải lên :
19/02/2014, 12:20
... APs References Davies, D.R (1990) The structure and function of the aspartic proteinases Annu Rev Biophys Biophys Chem 19, 189–215 Dunn, B.M (2002) Structure and mechanism of the pepsin-like family ... many different and diverse functions, including specific protein processing (e.g rennin, cathepsin D and yapsins), protein degradation (e.g gastric enzymes such as chymosin, pepsin and gastricsin) ... atypical and their localizations are unexpected New questions concerning functional significance and specialization of this multigene family of proteases are now starting to be addressed and will...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
Ngày tải lên :
19/02/2014, 12:20
... investigation and understanding of their structure- activity relationships, may start to provide a rational way to develop additional pharmacological tools for the elucidation of nAChR structure and function ... a5 and/ or b3 subunit [12] The a5 and b3 subunits are very similar in sequence and both appear Neuronal nAChRs are present throughout the central and peripheral nervous system, at both pre- and ... protein has structural and functional homology to the extracellular ligand binding domain of the nAChR, and likewise assembles into pentamers Ó FEBS 2004 unable to form functional channels in...
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf
Ngày tải lên :
19/02/2014, 16:20
... Graether and B D Sykes (Eur J Biochem 271) Fig Fish AFP structures and model The structures of the fish AFPs are shown as ribbon diagrams with coil structure shown as yellow, a-helices as red and b-strands ... [31,32,36] and their threedimensional structures were determined [34,37–40] In subsequent sections, we describe the structure and dynamics of each protein, and present a comparison of sbwAFP and TmAFP ... other and with proteins that have a similar fold Structure of sbwAFP and TmAFP The structure of sbwAFP has been determined by X-ray ˚ crystallography to 2.5 A and by NMR at both 30 °C and °C...
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Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
Ngày tải lên :
06/03/2014, 11:20
... three antiparallel strands (1, and 7) and strand 6, which is parallel to strand b-Strands are located between the four a-helices (a1, 278–294; a2, 305–313; a4, 374–381; and a5, 397–405), with ... elements: b-strands (b3, 329–335; b4, 339–344; and b5, 367–372) and a distorted a-helix (a3, 348–356) (Fig 3B,C) The three b-strands of the minidomain are all antiparallel, and form a single b -structure ... the structure of the protein core (residues 277–328 and 373–413) in solution and in the solid state, and indicates their similarity A superposition of the C-domain NMR structure on the crystal structure...
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Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc
Ngày tải lên :
07/03/2014, 00:20
... between strands E and F in transthyretin The two transthyretin dimers associate, via nonpolar interactions, between the loops joining stands G and H with the loops joining strands A and B, making ... between the structures of TLP and transthyretins are found in the loop connecting b-strands B and C, which is highly exposed to the solvent in TLP [17] Interruptions in the b-strands A, G and H are ... S dublin TLP and zebrafish TLP are found in the flexible portions of strands B and C that protrude towards the solvent and in the conformation of the long loop connecting strands D and E [17] Greater...
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Báo cáo khoa học: Structure and function of KH domains docx
Ngày tải lên :
07/03/2014, 05:20
... single-stranded DNA recognition by KH domains: solution structure of Structure and function of KH domains 24 25 26 27 28 29 30 31 32 33 34 35 36 a complex between hnRNP K KH3 single-stranded DNA EMBO ... string [12] In the protein DNA complex, each KH domain interacts with a separate ssDNA recognition sequence, and a Structure and function of KH domains Fig Crystal structure of Nova-2 KH3 bound ... Valverde et al Structure and function of KH domains A B C Fig 10 Crystal structure of tandem type II KH domains of NusA in complex with RNA The tandem KH1–KH2 domains of NusA recognize RNA ligand 5¢-GAACUCAAUAG...
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Báo cáo khoa học: Structure and function of N-acetylglucosamine kinase Identification of two active site cysteines pptx
Ngày tải lên :
08/03/2014, 10:20
... Ó FEBS 2002 Structure and function of GlcNAc kinase (Eur J Biochem 269) 4213 Fig De novo and salvage pathway of UDP-GlcNAc biosynthesis EXPERIMENTAL ... independent expressions Ó FEBS 2002 Structure and function of GlcNAc kinase (Eur J Biochem 269) 4215 able GlcNAc kinase activities, indicating a successful functional expression However, these ... C131 and C143 Their counterparts in glucokinase are C233 and C252 Mutations of these cysteines to serines have very similar effects on enzyme activity and substrate binding in glucokinase and...
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Day one nucleic acid structure and function
Ngày tải lên :
13/03/2014, 16:42
... double-stranded DNA λ phage 48,500 Linear double-stranded DNA T7 phage 40,000 Linear double-stranded DNA M13 phage 6,400 Closed-circular single-stranded DNA MS2 phage 3,600 Linear single-stranded ... 6,000,000,000 Linear double-stranded DNA Fruit fly 270,000,000 Linear double-stranded DNA HIV 9,700 Linear single-stranded RNA DNA molecules are packaged in the cell as structures called chromosomes ... nature? and What they look like? Genomes Source of DNA Size (bases) Type Escherichia coli 9,200,000 Closed-circular double-stranded DNA Bacillus subtilis 4,200,000 Closed-circular double-stranded DNA...
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Cell Structure and Function Functi
Ngày tải lên :
13/03/2014, 19:31
... form of DNA Prokaryotes – no membrane around the DNA Eukaryotes – DNA is within a membrane Cytoplasm with ribosomes Cytoplasm – fluid area inside outer plasma membrane and outside DNA region ... (4.5) Function – isolates the cell’s genetic material, DNA DNA directs/controls the activities of the cell • DNA determines which types of RNA are made • The RNA leaves the nucleus and directs ... 4-17, p.61 Nucleus DNA is arranged in chromosomes Chromosome – fiber of DNA with proteins attached Chromatin – all of the cell’s DNA and the associated proteins Nucleus Structure, continued...
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CELLS Structure and Function Structure and Function
Ngày tải lên :
13/03/2014, 19:31
... RER Functions of Eukaryotic Cell Features Structure Function( s) Golgi Apparatus Collects, modifies, packages and distributes proteins and lipids from ER Functions of Eukaryotic Cell Features Structure ... cell? Functions of Eukaryotic Cell Features Structure Function( s) Regulates passage of Plasma materials into and out of cell Membrane Cell-Cell Recognition Functions of Eukaryotic Cell Features Structure ... Plasma Membrane Functions of Eukaryotic Cell Features Structure Peroxisome Function Removes harmful oxidants from cells Functions of Eukaryotic Cell Features Structure Mitochondrion Function Captures...
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Báo cáo khóa học: S-(2,3-Dichlorotriazinyl)glutathione A new affinity label for probing the structure and function of glutathione transferases potx
Ngày tải lên :
16/03/2014, 16:20
... buffer, pH 7.0, and its UV spectra were recorded between 250 and 190 nm Molecular modelling Structure manipulations and analysis were performed using the PYMOL software [41] Results and Discussion ... SDTG–GST I covalent complex was then lyophilized and stored at )20 °C The lyophilized SDTG-modified enzyme was dissolved in M urea and incubated with N-ethylmaleimide to block free -SH groups, and then ... system, and by HPLC on a C18 reverse-phase column It was found to be at least 98.4% pure Fig Structure of SDTG (A) and time course of inactivation of recombinant GST I by SDTG at pH 6.5 and 25...
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Báo cáo khoa học: Multiple effects of DiS-C3(5) on mitochondrial structure and function pot
Ngày tải lên :
16/03/2014, 18:20
... Education, Science, and Culture of Japan, and a fellowship from Katayama Chemical Industries, Co., Ltd (Osaka) to T.Y Ó FEBS 2004 Effects of DiS-C on mitochondrial structure and function (Eur J Biochem ... found DiS-C3(5) to show multiple effects on the mitochondrial structure and function, effects 11 dependent on both its concentration and the Pi status Acknowledgements This work was supported by ... interpretation, we further characterized the actions of DiS-C3(5) on the mitochondrial structure and function and compared them with those of Ca2+, known as a typical PT inducer Like that of Ca2+,...
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Báo cáo khoa học: Human haptoglobin structure and function – a molecular modelling study pptx
Ngày tải lên :
23/03/2014, 06:20
... C1R (PDB code: 1GPZ [27]) and of the modelled structures of HPT1 and HPT2 HPT1 residue Cys15 and HPT2 residues Cys15 and Cys74 are shown in spacefill representation This and the following figures ... and C1R (A), and between HPT2 and C1R (B) Conserved residues are shaded in grey; Cys residues are highlighted in yellow Above the sequence alignment, red, green and magenta bars indicate a- and ... avoiding the unlikely occurrence of insertions and deletions within template secondary -structure elements The HPT1 covalent dimer and the HPT2 covalent trimer were constructed using the molecular...
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Báo cáo khoa học: Quaternary structure and functional properties of Penaeus monodon hemocyanin docx
Ngày tải lên :
23/03/2014, 13:20
... in Table 1, C or I, and, to some extent, also I* and C* The lower stability of Hc from nonpeneid Crustacea yields a structure where divalent ions (such as Ca2+ and Mg2+) and pH regulate the oligomerization ... Beltramini et al P monodon hemocyanin structure and function equilibrium constant, lo, describes the ratio of conformations r and t in the absence of ligand: lo ¼ ½t0 ½r0 Three-state MWC ... cloning of hemocyanin cDNA from Penaeus vannamei (Crustacea, Decapoda): structure, evolution and physiological aspects FEBS Lett 407, 153–158 41 Mangum CP & Weiland AL (1975) The function of hemocyanin...
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