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calcium distribution in the body

Tài liệu Color Atlas of Pharmacology (Part 3): Distribution in the Body docx

Tài liệu Color Atlas of Pharmacology (Part 3): Distribution in the Body docx

Sức khỏe giới tính

... Plasma ProteinsHaving entered the blood, drugs maybind to the protein molecules that arepresent in abundance, resulting in the formation of drug-protein complexes.Protein binding involves primarily ... from binding sites onplasma proteins. Binding to plasma pro-tein is equivalent to a depot in prolong-ing the duration of the effect by retard-ing elimination, whereas the intensityof the effect ... area in the sche-matic drawing, bottom left) and acts asa continuous barrier between the twospaces separated by the cell layer – in the case of the gut, the intestinal lumen(dark blue) and the...
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Báo cáo khóa học: Acharan sulfate, the new glycosaminoglycan fromAchatina fulica Bowdich 1822 Structural heterogeneity, metabolic labeling and localization in the body, mucus and the organic shell matrix docx

Báo cáo khóa học: Acharan sulfate, the new glycosaminoglycan fromAchatina fulica Bowdich 1822 Structural heterogeneity, metabolic labeling and localization in the body, mucus and the organic shell matrix docx

Báo cáo khoa học

... belocated in the body of this species using alcian blue stainingand it was suggested to be the main constituent of the mucus. In the present work, we provide further information on the structure ... sulfate in the snail body by alcian blue staining and showed that it ismainly secreted into the outer surface of the body as amucous material from internal granules [11]. The mucussecreted on the ... assess the alteration in the degree of sulfation of GAGs synthesized under the in uence of the inhibitors.Finally, Achatina fulica is an intermediate host toAngiostrongylus cantonensis [13], the...
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Tài liệu Organic matter distribution of the root zone in a constructed subsuface flow wetland pptx

Tài liệu Organic matter distribution of the root zone in a constructed subsuface flow wetland pptx

Điện - Điện tử

... wetland in tropical countries for domestic wastewater treatment. The linear decreasing OM distribution to the increasing vertical and horizontal flow direction is confirmed as the hypothesis in ... wetland in Can Tho University’s campus, Vietnam. The linear decreasing organic matter distribution to the increasing vertical and horizontal flow direction is confirmed as the hypothesis in highly ... The hypothesis is the OM distribution in sand bed descending linearly to the flow direction. 2. Materials and methods Sand sampling was done during January 2007 in the experimental constructed...
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Tài liệu HIGHLIGHTS OF THE AUTHORISATION REQUIREMENTS FOR FUND DISTRIBUTION IN HONG KONG doc

Tài liệu HIGHLIGHTS OF THE AUTHORISATION REQUIREMENTS FOR FUND DISTRIBUTION IN HONG KONG doc

Quỹ đầu tư

... Commission (the “SFC”) .3February 2012PwC3. Hong Kong Offering Document• The Hong Kong Offering Document of a scheme should contain, inter alia, the following information: Constitution of the ... existence); A letter nominating an individual to be an Approved Person of the scheme, containing the individual's details; The Hong Kong Representative related undertakings (where applicable); ... else acting, or refraining to act, in reliance on the information contained in this publication or for any decision based on it. © 2012 PricewaterhouseCoopers Limited. All rights reserved. In this...
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Tài liệu Báo cáo khoa học: The calcium-induced switch in the troponin complex probed by fluorescent mutants of troponin I doc

Tài liệu Báo cáo khoa học: The calcium-induced switch in the troponin complex probed by fluorescent mutants of troponin I doc

Báo cáo khoa học

... Ca2+signal is related to the N-domain. Further, the disruption of the sites in the C-domain affects the loweraffinity part of the signal. The difference in the second partof the curve, however, is ... data sets, the results for 5HW in the N-domainof TnC, in the inhibitory region of TnI and at position 121of TnI, followed the Ca2+-binding to the N-domain of TnC. The variation in Kdand ... havemainly a structural function in maintaining the organizationof the Tn [7–9,45]. The function of the C-terminal region ofTnI is less understood. Mapping of the TnI interactionsFig. 5. Calcium...
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Tài liệu Báo cáo khoa học: Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain ppt

Tài liệu Báo cáo khoa học: Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain ppt

Báo cáo khoa học

... can be oxidized in brain homogenates and that catalase is involved in the accumulation of acetaldehyde in the brain [27], explainingits presence despite the absence of ADH1 and the factthat acetaldehyde ... drinking [30].Retinoic acid has been implicated in many importantfunctions during development, including development of the brain [31,32]. Accordingly, Adh4 expression has beendetected in the ... [34]. Furthermore, a remarkable number of proteinsinvolved in retinoid-related metabolism (retinoic acidreceptors, cellular binding proteins and oxidizing enzymes)have been mapped within the adult...
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Báo cáo khoa học: Spatio-temporal distribution of fatty acid-binding protein 6 (fabp6) gene transcripts in the developing and adult zebrafish (Danio rerio) pptx

Báo cáo khoa học: Spatio-temporal distribution of fatty acid-binding protein 6 (fabp6) gene transcripts in the developing and adult zebrafish (Danio rerio) pptx

Báo cáo khoa học

... lipid-binding protein, intesti-nal 15 kDa protein, ileal bile acid-binding protein andgastrotropin, reflecting the speculations of authors onits intracellular function(s). In vitro binding assaysrevealed ... according to the tissue from which they were initially isolated, e.g. liver-type fatty acid-binding protein (L-FABP), brain-typefatty acid-binding protein (B-FABP), intestinal-typefatty acid-binding ... anintense hybridization signal in the distal region of the intestine (Fig. 6, 1A) and in the adrenal homolog of the kidney (Fig. 6, 1D). Less-intense hybridization sig-nals were observed in the...
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Báo cáo khoa học: The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco⁄endoplasmic reticulum calcium stores ppt

Báo cáo khoa học: The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco⁄endoplasmic reticulum calcium stores ppt

Báo cáo khoa học

... MagicRed-Cathepsin B substrate wasadded to the cells during the last 30 min of an experimentaccording to the manufacturer’s instructions. Calcium imagingFor dye loading, Fluo-4 was dissolved in in ... [9,10].Beclin 1, a class III phosphatidylinositol 3-kinase-interacting protein [11], plays a role in promotingautophagy [12]. Beclin 1 contains a Bcl-2-bindingdomain which may serve as a point of ... through the interaction of the anti-apoptotic proteins Bcl-2 and Bcl-XLwith Beclin 1. However, the nature of the interaction, either in promoting or blocking autophagy, remainsunclear. Here, using...
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Báo cáo Y học: Probing intermolecular protein–protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET) potx

Báo cáo Y học: Probing intermolecular protein–protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET) potx

Báo cáo khoa học

... FEBS 2002Agonist-induced rearrangement of the 7TMs in the CaR homodimer?One of the goals of the present study was to investigate,whether the activating twist in the ATD dimer of the familyC GPCR ... agonist-inducedalterations in BRET signal intensities reflecting 7TM dimerrearrangement as a result of the activating twist in the ATDsof the CaR homodimer. Further investigations into the signal ... Homodimerization of CaR in living cells (Eur. J. Biochem. 269) 5077Probing intermolecular protein–protein interactions in the calcium- sensing receptor homodimer using bioluminescenceresonance energy...
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Báo cáo khoa học: NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube pptx

Báo cáo khoa học: NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube pptx

Báo cáo khoa học

... and the C-terminal aminoacids 370±392 (Y163). Clone Y198 encoded the full-lengthcDNA of the calcium and integrin binding protein (CIB) in frame with the GA L4 AD.Mapping of regions involved in ... analysed using a L SM510 laser scanningconfocal microscope (Zeiss).RESULTSNBR1 interacts with the PKC zeta interacting proteinFEZ1 and the calcium and integrin binding protein CIB In order ... zinc binding domain originally thought to belong to the B-box family of zinc binding domains and a n octicosapep-tide sequence (OPR) also thought to be involved in divalentcation binding. The...
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Báo cáo Y học: Interaction of the anterior fat body protein with the hexamerin receptor in the blowfly Calliphora vicina pot

Báo cáo Y học: Interaction of the anterior fat body protein with the hexamerin receptor in the blowfly Calliphora vicina pot

Báo cáo khoa học

... proteins in two-hybrid experiments. On the other hand, the use ofantibodies against AFP in in vitro and in vivo experimentsinvestigating hexamerin uptake by the anterior fat body may g ive insights ... further experiments in twodistinct areas. On the one hand, the binding domains ofAFP and the hexamerin receptor could be m apped in detailby functional dissection using truncated prey proteins ... IgG. (A) In the border region of anterior (aF) and central fat body (cF), AFP-immunostaining appears only in the anterior fat body. (B) In a single fat body cell of the anterior fat body, AFP...
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Báo cáo khoa học: New evidence for the role of calcium in the glycosidase reaction of GH43 arabinanases pot

Báo cáo khoa học: New evidence for the role of calcium in the glycosidase reaction of GH43 arabinanases pot

Báo cáo khoa học

... optimizing binding of the carbohydrate chain in the cleft, and resulting in trioses as products. Theseobservations suggest that, by blocking one of the endsof the binding cleft, loop III in exo-ABN ... arranged in a distortedb-barrel-like configuration (shown in yellow). The hairpin that joinsblades IV and V in the N-terminal domain and interacts with the C-terminal domain is shown in red.Fig. ... of the ends of the binding cleft (Fig. 5). In fact, in the structure of the exo-ABN complex witharabinohexose [15], this loop makes the reducing endof the carbohydrate chain bend towards the...
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Selective Distribution of Luxury Goods in the Age of e-commerce An Economic Report for CHANEL doc

Selective Distribution of Luxury Goods in the Age of e-commerce An Economic Report for CHANEL doc

Tiếp thị - Bán hàng

... vertically integrate into internet retailing. Vertical integration into internet retailing would resolve the incentive issue because the manufacturer would fully take into account the incentive ... for restraints on internet distribution than they are in the case of any other distribution channel. Distribution over the internet should therefore not be treated differently as to the legality ... which includes a margin on the manufacturing cost. Because it includes this margin, the “marginal cost” which the independent retailer faces is higher than the marginal cost that an integrated...
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Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/– pdf

Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/– pdf

Báo cáo khoa học

... Itwould be interesting to determine whether it is suckling, like in the case of LRP [21], or weaning, as in the case of LDLR[24], which triggers the increase of LSR seen in liver, as suchan induction ... that were carried in apo B48-containing lipoproteins resembling remnants. Nevertheless, in LDLR-deficient mice the increase in TG levels was muchsmaller than that obtained in RAP overexpression ... measured in the postprandial stage [3]. The present work was u ndertaken to determine the distribution of LSR mRNA and protein in murine organs,and whether this distribution was c ompatible with the alleged...
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Báo cáo khoa học: Inhibition of the mitochondrial calcium uniporter by the oxo-bridged dinuclear ruthenium amine complex (Ru360) prevents from irreversible injury in postischemic rat heart docx

Báo cáo khoa học: Inhibition of the mitochondrial calcium uniporter by the oxo-bridged dinuclear ruthenium amine complex (Ru360) prevents from irreversible injury in postischemic rat heart docx

Báo cáo khoa học

... located in the intermembrane space, which participate in the apoptotic death signaling [26,27].An important limitation in assessing the relevanceof mPTP in I⁄ R injury in the intact heart is the Fig. ... nmolÆmg)1Æmin)1 in the mitochondrial fraction, indicatingsarcolemmal contamination in the microsomal fraction. The discrepancy between our binding results andother reports showing that Ru360has ... treatment were nor-malized in each group. (C) Specific [3H]ryanodine binding was deter-mined in a medium containing 100 lM free Ca2+to maintain the calcium release channel in sarcoplasmic reticulum...
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