... Plasma Proteins Having entered the blood, drugs may bind to the protein molecules that are present in abundance, resulting in the formation of drug-protein complexes. Protein binding involves primarily ... from binding sites on plasma proteins. Binding to plasma pro- tein is equivalent to a depot in prolong- ing the duration of the effect by retard- ing elimination, whereas the intensity of the effect ... area in the sche- matic drawing, bottom left) and acts as a continuous barrier between the two spaces separated by the cell layer – in the case of the gut, the intestinal lumen (dark blue) and the...
Ngày tải lên: 22/01/2014, 00:20
... be located in the body of this species using alcian blue staining and it was suggested to be the main constituent of the mucus. In the present work, we provide further information on the structure ... sulfate in the snail body by alcian blue staining and showed that it is mainly secreted into the outer surface of the body as a mucous material from internal granules [11]. The mucus secreted on the ... assess the alteration in the degree of sulfation of GAGs synthesized under the in uence of the inhibitors. Finally, Achatina fulica is an intermediate host to Angiostrongylus cantonensis [13], the...
Ngày tải lên: 16/03/2014, 16:20
phase equilibria and fluid properties in the chemical industry estimation and correlation
Ngày tải lên: 02/04/2014, 16:19
Effect of urban emissions on the horizontal distribution of metal concentration in sediments in the vicinity of Asian large cities
Ngày tải lên: 05/09/2013, 09:08
A CFD analysis on the effect of ambient conditions on the hygro-thermal stresses distribution in a planar ambient airbreathing PEM fuel cell
Ngày tải lên: 05/09/2013, 14:58
Chapter 2: Pressure Distribution in a Fluid
... along the slanted tube, what is the actual pressure difference being measured? Solution: The volume of the fluid rising into the tube, π d 2 ∆h/4, must equal the volume decrease in the ... bottom. The pressure at point B is 156 kPa. Find (a) the pressure in the air space; and (b) the force on the top of the insert. Neglect air pressure outside the tank. Solution: (a) The pressure ... Pressure Distribution in a Fluid 97 2.74 Find the height H in Fig. P2.74 for which the hydrostatic force on the rect- angular panel is the same as the force on the semicircular panel below. Find...
Ngày tải lên: 23/10/2013, 21:15
Tài liệu Organic matter distribution of the root zone in a constructed subsuface flow wetland pptx
... wetland in tropical countries for domestic wastewater treatment. The linear decreasing OM distribution to the increasing vertical and horizontal flow direction is confirmed as the hypothesis in ... wetland in Can Tho University’s campus, Vietnam. The linear decreasing organic matter distribution to the increasing vertical and horizontal flow direction is confirmed as the hypothesis in highly ... The hypothesis is the OM distribution in sand bed descending linearly to the flow direction. 2. Materials and methods Sand sampling was done during January 2007 in the experimental constructed...
Ngày tải lên: 24/01/2014, 00:20
Tài liệu HIGHLIGHTS OF THE AUTHORISATION REQUIREMENTS FOR FUND DISTRIBUTION IN HONG KONG doc
... Commission (the “SFC”) . 3 February 2012 PwC 3. Hong Kong Offering Document • The Hong Kong Offering Document of a scheme should contain, inter alia, the following information: Constitution of the ... existence); A letter nominating an individual to be an Approved Person of the scheme, containing the individual's details; The Hong Kong Representative related undertakings (where applicable); ... else acting, or refraining to act, in reliance on the information contained in this publication or for any decision based on it. © 2012 PricewaterhouseCoopers Limited. All rights reserved. In this...
Ngày tải lên: 19/02/2014, 14:20
Tài liệu Báo cáo khoa học: Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain ppt
... can be oxidized in brain homogenates and that catalase is involved in the accumulation of acetaldehyde in the brain [27], explaining its presence despite the absence of ADH1 and the fact that acetaldehyde ... drinking [30]. Retinoic acid has been implicated in many important functions during development, including development of the brain [31,32]. Accordingly, Adh4 expression has been detected in the ... [34]. Furthermore, a remarkable number of proteins involved in retinoid-related metabolism (retinoic acid receptors, cellular binding proteins and oxidizing enzymes) have been mapped within the adult...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: Spatio-temporal distribution of fatty acid-binding protein 6 (fabp6) gene transcripts in the developing and adult zebrafish (Danio rerio) pptx
... lipid-binding protein, intesti- nal 15 kDa protein, ileal bile acid-binding protein and gastrotropin, reflecting the speculations of authors on its intracellular function(s). In vitro binding assays revealed ... according to the tissue from which they were initially isolated, e.g. liver- type fatty acid-binding protein (L-FABP), brain-type fatty acid-binding protein (B-FABP), intestinal-type fatty acid-binding ... an intense hybridization signal in the distal region of the intestine (Fig. 6, 1A) and in the adrenal homolog of the kidney (Fig. 6, 1D). Less-intense hybridization sig- nals were observed in the...
Ngày tải lên: 07/03/2014, 06:20
Báo cáo Y học: Interaction of the anterior fat body protein with the hexamerin receptor in the blowfly Calliphora vicina pot
... proteins in two-hybrid experiments. On the other hand, the use of antibodies against AFP in in vitro and in vivo experiments investigating hexamerin uptake by the anterior fat body may g ive insights ... further experiments in two distinct areas. On the one hand, the binding domains of AFP and the hexamerin receptor could be m apped in detail by functional dissection using truncated prey proteins ... IgG. (A) In the border region of anterior (aF) and central fat body (cF), AFP-immunostaining appears only in the anterior fat body. (B) In a single fat body cell of the anterior fat body, AFP...
Ngày tải lên: 08/03/2014, 22:20
Selective Distribution of Luxury Goods in the Age of e-commerce An Economic Report for CHANEL doc
... vertically integrate into internet retailing. Vertical integration into internet retailing would resolve the incentive issue because the manufacturer would fully take into account the incentive ... for restraints on internet distribution than they are in the case of any other distribution channel. Distribution over the internet should therefore not be treated differently as to the legality ... which includes a margin on the manufacturing cost. Because it includes this margin, the “marginal cost” which the independent retailer faces is higher than the marginal cost that an integrated...
Ngày tải lên: 16/03/2014, 09:20
Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/– pdf
... It would be interesting to determine whether it is suckling, like in the case of LRP [21], or weaning, as in the case of LDLR [24], which triggers the increase of LSR seen in liver, as such an induction ... that were carried in apo B48- containing lipoproteins resembling remnants. Nevertheless, in LDLR-deficient mice the increase in TG levels was much smaller than that obtained in RAP overexpression ... measured in the postprandial stage [3]. The present work was u ndertaken to determine the distribution of LSR mRNA and protein in murine organs, and whether this distribution was c ompatible with the alleged...
Ngày tải lên: 16/03/2014, 18:20
EFFICIENCY AND DISTRIBUTION IN CONTRACT FARMING: THE CASE OF INDIAN POULTRY GROWERS pdf
... buildings, labor, and other variable inputs such as electricity and disinfectants. Using the information on input sharing, Table 5 computes the total value of variable inputs and the value of inputs ... column in Table 12 is the IV counterpart to the OLS results in the second column in Table 9 assuming homogenous treatment effects while the third column in Table 13 is the IV counterpart to the ... heterogenous, then additional controls in the form of interactions of the contract dummy with the demeaned explanatory variables must be included (Wooldridge, 2002). These estimates are contained in the...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo " Quantitative distribution of groundwater chemical components in the Red River Delta based on frequency analysis " pot
... characterized by a fine grain size and coarsegrainsize[4,5].Finesedimentscompos ed mainlyofsand in the lowerpartandweathered clay in the upper part of VinhPhuc Formation (Q 1 3 vp). ... are in accordancewithnormal distribution, while otherions are in accordance with skew distribution. In the first case, the value of mean equals the value of median,but in the secondcase,thesetwovaluesshouldbe ... percentage. In general, the higher the intervalofconcentration, the less quantity of samples is. So that, the freq uency distribution isskewedto the left(Fig.7). In this case, the averagevalueissignificantlydifferent from the median.Indeed, the averagevalueequals 140.88mg/l,while the medianequals26.37mg/l with...
Ngày tải lên: 22/03/2014, 12:20
Báo cáo khoa học: Liver receptor homolog-1 localization in the nuclear body is regulated by sumoylation and cAMP signaling in rat granulosa cells docx
... Nuclear body localization of LRH-1 was suppressed by forskolin and cholera toxin. Forskolin treatment obviously in uences the expression of members involved in the SUMO pathway. The results obtained ... is attenuated by the cAMP signaling pathway. Our studies further indicate a novel regulatory mechanism of cAMP signaling for altering the sumoylation cycle, involving modulating the expression ... 1 (Ftz-F1). LRH-1 is mainly expressed in tissues derived from the gut endoderm, including the liver, pancreas and intestine, and high levels of LRH-1 are also found in the ovary [1,2]. LRH-1...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo " Distribution of Arsenic, Copper, Lead, Zinc elements in water and soils of sulfur deposits in the North West of Hanoi " pptx
Ngày tải lên: 28/03/2014, 15:20
Body composition in the elderly: Reference values and bioelectrical impedance spectroscopy to predict total body skeletal muscle mass pot
... offers information of ICW and ECW distribution, and FFM is predicted from these. Body fat (BF) is generally calculated as the difference between body weight (BW) and FFM. There is an increasing interest ... i.e. R pred 2 will explain the expected variability in prediction of new observations. 16 R 2 represents the coefficient of determination for the regression equation among the observed subjects. SSE is the sum ... fatness and body fat index (BFI) (women 9.6 and men 7.1). Average fat free mass index (FFMI) was similar for women and slightly higher for Italian men. The differences in body composition in the Swiss,...
Ngày tải lên: 28/03/2014, 20:20