bách khoa y học mở
Báo cáo y học: "Molecular Virology of Hepatitis C Virus (HCV): 2006 Update"
Ngày tải lên :
02/11/2012, 10:00
... Staff Physician at the Department of
Gastroenterology and Hepatology, University Hospital
Freiburg, Germany. Since 2004 he is the head of the
Division of Gastroenterology and Hepatology, Centre ... polymerase. Mol
Cell 2005; 19: 111-22.
Author biography
Hubert E. Blum, MD, is the chairman of the Department
of Gastroenterology and Hepatology, University Hospital
Freiburg, Germany. His ... NS5B
The key enzyme of the replicase that promotes
synthesis of new RNA genomes is the NS5B RNA-
dependent RNA polymerase (RdRp). NS5B is a tail-
anchored protein, characterized by a transmembrane...
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Báo cáo y học: "Monte Carlo Commissioning of Low Energy Electron Radiotherapy Beams using NXEGS Software"
Ngày tải lên :
03/11/2012, 10:05
... D(d
1
-d
5
);
Y( d
1
)Y( d
1
-d
3
)Y( d
1
-d
3
)X(d
1
-d
5
); Y( d
1
-d
5
)
120
P; Y( d
2
)P; D(d
2
); P; D(d
2
); P; D(d
2
); P; D(d
1
-d
4
);
Y( d
1
)Y( d
1
-d
3
)Y( d
1
-d
3
)X(d
1
-d
5
); Y( d
1
-d
5
)
Total ... D(d
2
); Y( d
2
,d
5
)P; D(d
1
);X(d
3
,d
4
); P; D(d
2
); X(d
3
,d
4
)P; D(d
1
-d
4
); P; D(d
1
-d
5
);
Y( d
1
,d
2
,d
5
)Y( d
1
,d
2
,d
5
)X(d
1
-d
5
); Y( d
1
-d
5
)X(d
1
-d
5
); Y( d
1
-d
5
)
110
P; Y( d
2
)P; ... given by only the first two primary rows of the table. One readily sees from the table that
for each beam we use as few as six and as many as 48 scans to perform the commissioning, a process
yielding...
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Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx
Ngày tải lên :
21/02/2014, 15:20
... endothelial lipase [1,2]. The
primary function of LPL is triglyceride hydrolysis in
triglyceride-rich lipoproteins, such as chylomicron and very
low density lipoprotein (VLDL) particles, which ... the MARKIT-F LPL kit, and
chromatography fractions were analyzed by Western blotting with
LPL polyclonal antibody 7640 (B).
Fig. 2. Heparin affinity of wild-type and basic amino acid–substituted
LPL. ... purified from a
prokaryotic system were eluted from the heparin affinity
column at extremely low efficiency, the proteins produced in
the in vitro system were measured for heparin affinity
(Table 1). The...
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Báo cáo Y học: Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules pptx
Ngày tải lên :
08/03/2014, 09:20
... [20]
Palmitoyl-Thr-Val-Ser-Tyr-Glu-Leu-OH 0.5 Kinetic analysis [20]
Palmitoyl-Tyr-Glu-Leu-OH 0.15 Kinetic analysis [21]
Palmitoyl-Tyr-Glu-(
L
-threonine)-OH 0.05 Kinetic analysis [21]
Palmitoyl-Tyr-Glu-(p-biphenyl-alanine)-OH ... the ribo-
nuclease H and DNA polymerase activities of HIV-1 reverse
transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthalde-
hyde hydrazone. Biochemistry 36, 3179–3185.
57. Arion,D.,Sluis-Cremer,N.,Min,K ... immunodeficiency virus type 1
reverse transcriptase dimer destabilization by 1-[spiro[4¢-amino-
2¢,2¢-dioxo-1¢,2¢-oxathiole-5¢,3¢-[2¢,5¢-bis-O-(tert-butyldimethylsi-
lyl)-beta-
D
-ribofuranosyl]]]-3-ethylthymine....
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Báo cáo Y học: Molecular cloning, bacterial expression and properties of Rab31 and Rab32 docx
Ngày tải lên :
08/03/2014, 16:20
... coupled
to keyhole limpet haemocyanin via their endogenous
(Rab31) or added (Rab32, Rab11A) cysteine residues, using
4-(N-maleimidomethyl) cyclohexane-1-carboxylate. Rabbits
were immunized by intradermal ... hydrolysis in t he absence or
presence of cytosol containing GAP activity [43]. Moreover,
Rab25 has considerable GTPase activity [43], although the
corresponding glutamine residue is naturally ... columns or antibody af®nity-
puri®ed on an UltraLink I odoacetyl column containing
covalently bound peptide. Bound antibody was visualized
using horse-radish peroxidase-conjugated donkey anti-
(rabbit...
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Báo cáo Y học: Molecular cloning and characterization of isomultiflorenol synthase, a new triterpene synthase from Luffa cylindrica, involved in biosynthesis of bryonolic acid ppt
Ngày tải lên :
08/03/2014, 23:20
... by b-amyrin synthase than to that by
cycloartenol synthase, an isomultiflorenol synthase is
expected to share greater sequence similarity with b-amyrin
synthase. In this study, we used the Glycyrrhiza ... of Luffa cylindrica Roem. by
heterologous hybridization with cDNA of Glycyrrhiza
glabra b-amyrin synthase. Expression of LcIMS1 in yeast
lacking endogenous oxidosqualene cyclase activity resulted
in ... N.,
Ikeshiro, Y. , Kushiro, T., Shibuya, M. & Ebizuka, Y. (2001)
Cloning and characterization of a cDNA encoding b-amyrin
synthase involved in glycyrrhizin and soyasaponin biosynthesis in
licorice....
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Báo cáo Y học: Monoterpene biosynthesis in lemon (Citrus limon) cDNA isolation and functional analysis of four monoterpene synthases pot
Ngày tải lên :
08/03/2014, 23:20
... monoterpene hydrocarbons
from [1-
3
H]neryl pyrophosphate and [1-
3
H]geranyl pyrophosphate
by soluble enzymes from Citrus limonum. Arch. Biochem. Biophys.
180, 318–327.
19. Maruyama, T., Ito, ... signals (only 16–18% identity) and the
coding sequences (only 48–51% identity), suggesting that
they have evolved separately.
This is confirmed by the phylogenetic analysis (Fig. 2).
The separate ... Cybernetics, Plant Research International, Wageningen, the Netherlands;
2
University of Wu
¨
rzburg,
Chair of Food Chemistry, Germany;
3
Laboratory of Plant Physiology, Wageningen University,...
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Báo cáo Y học: Molecular mechanisms underlying SHP-1 gene expression potx
Ngày tải lên :
08/03/2014, 23:20
... activity
in SKOV3 cells.
In our EMSA analyses, aside from the shifted band that
contained USF1 and USF2, we observed other shifted
bands (X and Y) . As bands X and Y were only partially
inhibited by ... Research Institute, University Health Network, Toronto, Ontario,
Canada;
2
Laboratory of Gynecologic Oncology, Department of Obstetric Gynecology and Reproductive Biology, Brigham and
Women’s Hospital, ... tyrosine kinases and phosphatases
are the key players in the regulation of protein tyrosine
phosphorylation. Among the known protein tyrosine
phosphatases, SHP-1 and SHP-2 are distinguished by...
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Báo cáo Y học: Molecular interaction of neutral trehalase with other enzymes of trehalose metabolism in the fission yeast Schizosaccharomyces pombe pdf
Ngày tải lên :
08/03/2014, 23:20
... metabolism is the hydro-
lysis of trehalose to glucose. This is catalyzed by the enzyme
neutral trehalase (NTH1), whose activity is regulated
by phosphorylation of the enzyme protein at serine ... 2B, affinity-purified Ntp1p–Ha6H from growing cells
displayed a typical pattern of neutral trehalase activity,
with low level of enzyme activity in unstressed cells that
increases strongly upon stress. ... disaccharide
trehalose is carried out by several enzymes that are widely
distributed and conserved among prokaryotes and eukary-
otes. One probable reason for this conservation is the ability
of trehalose to function...
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TỔNG QUAN Y HỌC MÔI TRƯỜNG potx
Ngày tải lên :
11/03/2014, 02:20
... đai Lửa Thái Bình
Dương, nơi thường xuyên chịu ảnh hưởng
của núi lửa hoạt động. Trong số n y hoạt
động mạnh nhất là ngọn Mayon cao 2.464 m.
Núi lửa n y từng phun trào 49 lần kể từ khi
được ... trong lịch sử năm
1616 và lần g y thiệt hại nặng nhất là năm
1814, khi nó làm chết hơn 1.200 người. Lần
phun trào nham thạch quy mô lớn gần đ y
nhất của Mayon là năm 1993.
...
Philippines quyết định nâng mức báo động
3 đối với Mayon, mức cảnh báo núi lửa sẽ
phun trào mạnh trong vòng vài tuần hoặc
vài ng y sắp tới.
24
Núi lửa Ambrym tại Vanuatu thuộc Nam Thái Bình dương
33
Cận...
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Báo cáo Y học: Molecular cloning of columbamine O-methyltransferase from cultured Coptis japonica cells pot
Ngày tải lên :
17/03/2014, 10:20
... CoOMT and the biosynthetic
enzymes involved in benzylisoquinoline alkaloid biosynthe-
sis, including berberine bridge enzyme [28–30] and (S)-N-
methylcoclaurine 3¢-hydroxylase (CYP80B1) [31], also ... S-adenosyl-
L
-methionine:
coclaurine N-methyltransferase; 4¢OMT, S-adenosyl-
L
-methionine:3¢-
hydroxy-N-methylcoclaurine 4¢-O-methyltransferase; SMT,
S-adenosyl-
L
-methionine:scoulerine 9-O-methyltransferase; ... M.H. (1990) S-adenosyl-
L
-methionine:
3¢-hydroxy-N-methyl-(S) -coclaurine-4¢-O-methyltransferase, a
regio- and stereoselective enzyme of the (S)-reticuline pathway.
Phytochemistry 29, 3505–3511.
12....
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Báo cáo Y học: Monitoring the structural consequences of Phe12 fi D-Phe and Leu15 fi Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf
Ngày tải lên :
17/03/2014, 10:20
... angle almost typical for the 3
10
helix.
In this region of the polypeptide chain, the secondary
structure is characterized also by the O
i
H
N
i þ 3
hydrogen
bonds, found in all 40
DYANA
structures ... Cushing’s syndrome, inflammatory dis-
eases, pre-eclampsia or preterm labour, anxiety and depres-
sion and a potentially great number of other disorders.
We have previously described the synthesis ... residue) in
DYANA
structural calculations [31]. Appropriate pseudo-
atom corrections were applied to methylene and methyl
hydrogens that were not stereospecifically assigned [32].
a-Aminoisobutyrilo...
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Giáo trình hóa đại cương - Đào Việt Hùng-ĐH Bách Khoa, Đại học Đà Nẵng pdf
Ngày tải lên :
19/03/2014, 05:20
... y (bão hoà). Các nguyên t chuyn
tip c chia thành 3 nhóm:
1. Nhóm c bn hay còn gi là nhóm d gm có 3 d y vi mi d y 10 nguyên t:
- D y 3d:
21
Sc (Scandi) →
30
Zn (Km)
- D y ... - Xenon) trên 5p. Gia các
nguyên t s và p n y các nguyên t chuyn tip d y 4d:
39
Y (Ytri) →
48
Cd (Cadimi).
3.1.6. Chu kỳ 6.
Chu k n y gm có 32 nguyên t. S phân b in t các ... tích trong nguyên t ca 2 nguyên t n y trng thái c bn bng
không.
4
Chương 1
MỞ ĐẦU
1.1. HOÁ HỌC VÀ NHIỆM VỤ CỦA HOÁ HỌC:
Hoá hc là mt trong nhng môn khoa hc c bn...
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