by laws in the city of toronto

Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx

Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx

... entrapped in the residual pellet which is not solubilized by urea Effect of dopamine on MPTP and MPP+ induced changes in kinetics of the aggregation of a-synuclein a-Synuclein was incubated in the ... shows the kinetics of aggregation of a-synuclein in the presence of 100 lm MPTP and the effect of 50 lm dopamine on the aggregation process Dopamine delayed the lag phase of aggregation marginally ... solid line), in the presence of 100 lM neurotoxin ( , dotted line), in the presence of 200 lM neurotoxin ( , dotted line) and in the presence of neurotoxin and 50 lM dopamine (h, dashed line) • 1692...

Ngày tải lên: 14/02/2014, 19:20

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Tom Swift in the City of Gold pot

Tom Swift in the City of Gold pot

... bales puffed to the loading gangways There was the puffing and whistling of the donkey engines as they hoisted into the big holds the goods intended for export At the side of the steamer were ... entrance to the underground city. " "What is the 'plain of the big temple,' Tom?" "Mr Illingway writes," said the lad, again referring to the letter, "that somewhere near the beginning of the tunnel ... Eradicate was assisting up the plank, that he partly hid them from sight, and the action of the two in covering their faces further aided them in disguising themselves, if such was their intention 43...

Ngày tải lên: 15/03/2014, 16:20

124 504 0
Summary of Ph.D thesis: A study on the embankment caculation method reinforced by geotextile in the construction of highway in Vet Nam

Summary of Ph.D thesis: A study on the embankment caculation method reinforced by geotextile in the construction of highway in Vet Nam

... the dangerous sliding surface of the embankment , and shear strain draw lines connecting points of maximum shear strain in the soil as well as the result of calculating the approximate form of ... form on the basis of elastic theory for the case of plane strain problem In the case of reinforced embankment , to determine the state of stress - deformation of the embankment below the horizontal ... as shown in the form 3.16 ) In the first step to finding solutions is the initial displacement of the system , the stiffness of geotextile to build the stiffness matrix is the slope of the first...

Ngày tải lên: 02/07/2014, 20:44

31 563 0
253. Chicago_ Some Big Places to See in the ''''City of the Big Shoulders'''' docx

253. Chicago_ Some Big Places to See in the ''''City of the Big Shoulders'''' docx

... TWO: Another big thing to see, and feel, is the weather After all, another name for Chicago is the "Windy City. " People turn their shoulders to the strong winds off Lake Michigan In winter, Chicago ... is known as the Loop There are many offices and stores The Loop includes the financial district around LaSalle Street The financial district is home to the Chicago Board of Trade, the Chicago ... building designs to see The Wrigley Building, near the Chicago River, opened in the early nineteen twenties This office building is hard to miss It is bright white Downtown Chicago, the business...

Ngày tải lên: 14/08/2014, 21:21

5 273 0
proceedings of the great democratic republican meeting in the city of new york, january 2, 1838 (1838)

proceedings of the great democratic republican meeting in the city of new york, january 2, 1838 (1838)

... property in their hands than by reference to their proceedings They were called together by hand at a public meeting held last spring in the Park of this city bills, posted in various parts of the city ... suddenly affected the financial condition of the nation, and placed the general government in an attitude of open hostility to the institutions of the States and the business interests of the people, ... toposlerity of the soil of the State and banking institutions, as the great cause of the existing unhappy condition of society" and that the proper means of relief was "the election of men who from their...

Ngày tải lên: 05/11/2014, 13:03

23 209 0
Monitoring of air pollution spread on the car free day in the city of veszprém

Monitoring of air pollution spread on the car free day in the city of veszprém

... proffesor in the Institute of Environmental Protection Engineering, Pannon University, Institute of Environmental Engineerinng, Veszprém, Hungary, Egyetem Street 10 The author’s major field of ... proffesor in the Institute of Environmental Protection Engineering, Pannon University, Institute of Environmental Engineerinng, Veszprém, Hungary, Egyetem Street 10 The author’s major field of ... lines signed the closed area, the green arrow shows the place of the elementary school, the white lines signed the way of the traffic and the red no entrance symbol shows where the traffic jam...

Ngày tải lên: 09/09/2015, 10:32

6 377 0
Equivalence in the translation of vietnamese cultural words in the book “wandering through vietnamese culture” by huu ngoc

Equivalence in the translation of vietnamese cultural words in the book “wandering through vietnamese culture” by huu ngoc

... non-lexicalization of the concepts, the lack of super ordinates of hyponyms etc The main contribution of this paper is to draw out the main ways of dealing with the hurdles by investigating how an experienced ... a basic “change of form”, by emphasizing the “intended in the text” as said “ Translation is rendering a written text into another language in the way the author intended in the text.” Hatim ... translating by stating that language is "the heart within the body of culture," the survival of both aspects being interdependent Linguistic notions of transferring meaning are seen as being only...

Ngày tải lên: 07/11/2012, 14:31

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Water Pollution Characterization by Pathogenic Indicators in Water Runoff in the Downtown of Hanoi, Vietnam

Water Pollution Characterization by Pathogenic Indicators in Water Runoff in the Downtown of Hanoi, Vietnam

... surface washoff are different depending on the sampling locations and rainfall patterns Time variation of pollutant concentration in road runoff showed increasing trend at the end of rainfall This ... be used as an indicator of mixing wastewater in water samples when collected under wet weather condition These results indicate the range of variation in the quality of surface runoff which makes ... after the sewerage system, by the streets in downtown Hanoi or due to the malfunctioning and overflowing of the septic systems Although individual households might contribute only minor amounts of...

Ngày tải lên: 05/09/2013, 10:15

10 541 1
A discourse analysis of presuppositions in the declaration of independence made by president ho chi minh = phân tích diễn ngôn các tiền giả định trong tuyên ngôn độc lập của chủ tịch hồ chí minh

A discourse analysis of presuppositions in the declaration of independence made by president ho chi minh = phân tích diễn ngôn các tiền giả định trong tuyên ngôn độc lập của chủ tịch hồ chí minh

... Strikingly, the definite article the is used most Such expressions as the earth, the world appear to be the fixed principles of using the articles in the field of 30 grammar In grammar, the ... action, responding to the arguments of the opponents and foreseeing opposing dangers 33 Secondly, in quoting the declarations of independence of America in 1776 and the declaration of the French ... discourse analysis involves the study of language in use A wide range of linguistic texts are explored in the study of discourse These might be in either spoken or written form, including a conversation...

Ngày tải lên: 14/12/2013, 00:41

47 1,5K 10
An analysis of errors made by high school student in the use of subject verb agreement in english writing = phân tích lỗi sai của học sinh PTTH về sự tương hợp giữa chủ ngữ và động từ trong văn viết tiếng anh

An analysis of errors made by high school student in the use of subject verb agreement in english writing = phân tích lỗi sai của học sinh PTTH về sự tương hợp giữa chủ ngữ và động từ trong văn viết tiếng anh

... However, they mainly focus on the theory of SVA To the best of my knowlege, very little research so far has been done in Vietnam on the error analysis in the area of English SVA In the thesis by Lơng ... students in the use of subject- verb agreement in English writing Aims of the study The study reported in this thesis aims to: - Identify the errors in using SVA in English writing made by high ... very kind For many students, they can not distinguish the meaning of "family" in the sentence (a) from the one in the sentence (b) They can not realize whether it refers to a singular unit or individual...

Ngày tải lên: 18/12/2013, 10:04

47 1,4K 9
The victorious laugh of love, frienship, justice and commonsence in the merchant of venice by shakespeare

The victorious laugh of love, frienship, justice and commonsence in the merchant of venice by shakespeare

... Friendship is the leading theme in this play It is the theme described from the beggining to the end of the story Everyone seems to be living in a warm world of friendship 35 The relationship ... enthusiasm in propagating the spirit of humanism in Greek and Roman culture, thanks to the extremely important invention of the printing machine, the number of ancient writers' readers increased ... placed their interest in humanbeings They agreed with the ancient thinkers in evaluating and exalting the dignity of humanbeings They considered men to be the creator of the world This period...

Ngày tải lên: 18/12/2013, 21:45

47 437 0
Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx

Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx

... copper binding could still allow domain swapping to occur It is of interest that a N-terminally truncated prion protein, lacking the copper binding domain is capable of domain swapping and forms ... an initial injection of lL copper chelate solution was followed by a further 29 injections of lL of Cu(II) into the protein in the sample cell stirred at 300 r.p.m Injections were separated by ... not bind copper Although the structure of the two proteins is almost identical, the sequences differ in a number of places, but in particular, stefin B has a number of histidines in the C-terminus...

Ngày tải lên: 19/02/2014, 06:20

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Tài liệu Báo cáo khoa học: Altered inactivation pathway of factor Va by activated protein C in the presence of heparin doc

Tài liệu Báo cáo khoa học: Altered inactivation pathway of factor Va by activated protein C in the presence of heparin doc

... activity of the reaction intermediate, FVaint This facilitated the determination of loss of FVa cofactor activity during the initial stage of inactivation and minimized the in uence of the k306 ... optimize further the positioning of the molecules Results APC-catalyzed inactivation of FVa in the presence of heparin Heparin strongly in uenced the time course of FVa inactivation by wild-type ... heparin binding To verify that the inhibition of APC-mediated FVa inactivation by heparin is related to the ability of heparin to bind APC, we used recombinant mutants of APC harboring mutations in...

Ngày tải lên: 19/02/2014, 13:20

13 655 0
Tài liệu Báo cáo Y học: The binding of lamin B receptor to chromatin is regulated by phosphorylation in the RS region ppt

Tài liệu Báo cáo Y học: The binding of lamin B receptor to chromatin is regulated by phosphorylation in the RS region ppt

... chromatin in eggs, binding through the RS region of LBR to linker DNA of chromatin seems to be predominant Then, the binding is supported by the interaction of the NM region and a protein(s) other ... protein(s) on chromatin These results also suggested that the binding of the RS region to chromatin DNA is superior to the binding of the NM region to the chromatin protein because the binding ... participate in the binding of LBR to sperm chromatin in eggs In the case of the binding of LBR to Fig Tryptic phosphopeptide analysis of GST-NK Beads bearing 20 lg GST–NK were incubated with 20 lL of...

Ngày tải lên: 22/02/2014, 04:20

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Báo cáo khoa học: Suppression of a cold-sensitive mutant initiation factor 1 by alterations in the 23S rRNA maturation region pdf

Báo cáo khoa học: Suppression of a cold-sensitive mutant initiation factor 1 by alterations in the 23S rRNA maturation region pdf

... [29–32] Taking these findings together, we suggest that the R69L mutant of IF1 allows premature subunit joining by either failing to discriminate between certain TIR elements in mRNA, or inducing a ... rRNA termini are present in both the 50S and the 70S fractions We then investigated whether the observed extended termini present in the 23S processing stem mutants were incorporated into the 50S ... termini, were identified in strains carrying the mutant plasmids pD1 and pD6, which carry mutations on the 5¢-side of the processing stem, gave rise to rRNA with the majority of termini in the...

Ngày tải lên: 06/03/2014, 00:21

12 439 0
Báo cáo khoa học: Gene expression silencing with ‘specific’ small interfering RNA goes beyond specificity – a study of key parameters to take into account in the onset of small interfering RNA off-target effects potx

Báo cáo khoa học: Gene expression silencing with ‘specific’ small interfering RNA goes beyond specificity – a study of key parameters to take into account in the onset of small interfering RNA off-target effects potx

... increase in the abundance of SREBF1 transcript in each cell type The efficiency of SREBF1 ⁄ siRNA1 was also investigated at the protein level by western blotting analysis of SREBF1 abundance in ... differences in exposure times during western blotting We also observed a slight increase in SREBF1 protein level triggered in the presence of the NT siRNA, in agreement with the slight increase in SREBF1 ... The role of sequence pairing in siRNA side effects is also supported by data showing that these effects can be dramatically reduced in the presence of another control, the RNA-induced silencing...

Ngày tải lên: 07/03/2014, 05:20

16 494 0
Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot

Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot

... ATP into contact in the absence of ATP, curcumin is then able to bind to the ATPase (possibly at the hinge region) locking the two domains together and therefore precluding ATP binding (i.e inhibiting ... concentrations of curcumin (25 mM ) the Km for the catalytic site is also possibly increased In order to further assess the possibility of curcumin affecting the interaction of ATP binding to the ATPase, ... assess curcumin binding to the Ca2þ-ATPase Titrations were performed by addition of either curcumin or ATPase and interpreted using Langmuir isotherms Binding can be described by the following equation:...

Ngày tải lên: 08/03/2014, 23:20

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BRANDS ARE BUILT IN THE CONSCIOUSNESS OF THE RECEIVER, NOT BY THE COMPANY potx

BRANDS ARE BUILT IN THE CONSCIOUSNESS OF THE RECEIVER, NOT BY THE COMPANY potx

... discounting this at an interest rate determined by the return required by the investor If the present value, including any residual value, is greater than the cost of the investment, then it is profitable ... wine was introduced The inventor was an Australian winemaker who was looking for a way to sell his red wine in greater volumes without the wine being ruined When a bottle of wine is opened, the ... preventing air from reaching the wine The modern container is made partly of plastic Bag -in- box sales were a big hit almost instantly Since then, bag -in- box – BIB – has grown into a global industry...

Ngày tải lên: 09/03/2014, 00:20

36 485 0
THE PART BORNE BY THE DUTCH IN THE DISCOVERY OF AUSTRALIA 1606-1765 pdf

THE PART BORNE BY THE DUTCH IN THE DISCOVERY OF AUSTRALIA 1606-1765 pdf

... voyage of discovery of 1642-1643, I was time and again struck by the fact that the part borne by the Netherlanders in the discovery of the continent of Australia is very insufficiently known to the ... west-coast of Australia; the discovery of this west-coast by the Dutch in and after 1616, and of the south-western extremity of the continent in 1622, constituting the main facts of the period ... was the sending out of a ship for the purpose of obtaining this "certain knowledge": there were rumours afloat of gold being found in New Guinea! [* See No II of the Documents.] On the 28th of...

Ngày tải lên: 15/03/2014, 03:20

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Báo cáo khoa học: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene doc

Báo cáo khoa học: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene doc

... the biosynthesis of desferrioxamine B in S pilosus indicated that the first step in the desferrioxamine biosynthesis is the decarboxylation of lysine by a lysine decarboxylase encoded by the desA ... [12] Therefore, binding of the iron regulator DmdR1 will interfere with RNA polymerase interaction and expression of the desferrioxamine cluster Indeed, binding of the pure DmdR1 protein to the ... iron box), explaining the regulation of desA expression by binding of DmdR1 to the iron box The same overlapping was found in S pilosus DmdR1 binds to the promoter region of desABCD in both S coelicolor...

Ngày tải lên: 16/03/2014, 11:20

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