... generic product entered the market at a significant discount to the brand name firm, and this discount grew larger as the number of generic competitors for a particular brand name product expanded ... policy, and government reimbursement controls.6 The focus of this paper is on the role and impact of patents and intellectual property protection in the discovery and development of new pharmaceutical ... competitive advantages of being first in the market, superior sales and service efforts, secrecy and complexity of productions and product technology, as well as patents Both studies found that the...
Ngày tải lên: 13/03/2014, 21:59
... on Applications and the Internet, 2003, pages 166-169, 27-31 Jan 2003 [19] G Rios and H Zha Exploring support vector machines and random forests for spam detection In Conference on Email and ... of networks and the productivity of users A vast array of new techniques have been evaluated in academic papers, and some have been taken into the community at large via open source products Anti-spam ... Outlook has also been tested and evaluated [18] Rios and Zha [19] also experiment with SVMs, along with random forests (RFs) and naive Bayesian filters They conclude that SVM and RF classifiers are...
Ngày tải lên: 22/03/2014, 22:25
Transparency in the German real estate market – Results and problems, chances and new developments doc
... standard land value Products from the Purchase Price Collection made from the land valuation board are the price contour maps In the price contour maps you can find a standard land value This standard ... standard land value is updated each year with the reporting date 1st January The most common types of standard land prices are values for: agricultural and forest areas rural and urban areas trade and ... transparency in the real estate market TAXATION (LAND TAX) The finance ministry of the lands Bavaria and Rheinland-Pfalz have worked out a new concept for land taxation in Germany The target is to simplify...
Ngày tải lên: 23/03/2014, 08:20
Chemical kinetics fundamentals and new developments docx
... i, j,/, and m, respect!vely; IXand Ix' are the reduced weights of reactants and products; Etr~l and E transl are the translational energies of reactants and products; and g (i,j -, l,m) and o ... A and B should be known Let [A(i)] = fg(i)[A] and [B(j)] = fa(j)[B] where fA(i) and fB(j) are the distribution functions of molecules A and B over quantum states i and j, respectively; [A] and ... is accepted that the A and C atoms and the BC and AB molecules are in the nondegenerated electronic states, and the AB and BC molecules can exist in different vibrational and rotational states...
Ngày tải lên: 23/03/2014, 21:21
RHEOLOGY - NEW CONCEPTS, APPLICATIONS AND METHODS potx
... North, New Zealand MacDiarmid Institute for Advanced Materials and Nanotechnology, New Zealand School of Chemical Sciences, University of Auckland, New Zealand Riddet Institute, Palmerston North, New ... distribution, and reproduction in any medium, provided the original work is properly cited 2 Rheology - New Concepts, Applications and Methods where, is the lag time, t is the time and x , y and z ... Liew Jian Ping, N N Ekere and Lim Seow Pheng Chapter Heliogeophysical Aspects of Rheology: New Technologies and Horizons of Preventive Medicine 39 Trofimov Alexander and Sevostyanova Evgeniya...
Ngày tải lên: 29/03/2014, 21:20
Genetic Engineering Basics New Applications and Responsibilities Part 14 doc
... in society, Wellington, New Zealand Small, B (2006, 10-12 January) GE and medicine: A comparison of NZ public and scientists' attitudes Paper presented at the New Zealand Bioethics Conference, ... New Zealand and Beyond Conference, Akaroa, New Zealand,1-5 February 2004 Small, B (2005) Genetic engineering: New Zealand public attitudes 2001, 2003 and 2005 Paper presented at the Talking Biotechnology: ... Responsibilities and rights of science in society: the case of placing human genes in other organisms Paper presented at the Technologies, Publics and Power: The Terrain of the 6th Framework in New Zealand and...
Ngày tải lên: 22/06/2014, 03:20
Genetic Engineering Basics New Applications and Responsibilities Part 1 pdf
... leading strand and lagging strand are both formed when it is unwound The leading strand allows replication to occur continuously and therefore needs only one primer, however, the lagging strand is ... responsible for genetic replication and expression, and how they can be utilized for expression of non-native constructs 4 Genetic Engineering – Basics, New Applications and Responsibilities In addition, ... have not been tested enough in the laboratory and in controlled field facilities to avoid unexpected and unintentional harm to our and other species and as well as the environment Prof Dr Hugo...
Ngày tải lên: 22/06/2014, 03:20
Genetic Engineering Basics New Applications and Responsibilities Part 3 pptx
... attB1 and attB2, attP1 and attP2, attL1 and attL2, and attR1 and attR2; a recombination reaction can occur only in the combinations of attB1 and attP1, attB2 and attP2, attL1 and attR1, or attL2 and ... free from the need for restriction endonucleases and DNA ligase, has a simple and uniform protocol, and offers highly efficient and reliable cloning and easy manipulation of fusion constructs Therefore, ... size and high copy number in E coli, preparation and handling of pUGW plasmids are very easy Fig Procedure for construction of pUGWs pUGW0 and pUGW2 are the starting vectors for construction of new...
Ngày tải lên: 22/06/2014, 03:20
Genetic Engineering Basics New Applications and Responsibilities Part 5 potx
... 70 Genetic Engineering – Basics, New Applications and Responsibilities homology with H parvula Hence, both enzymes are considered to be almost identical, and the similar effect of this mutation ... U31240) of the P pennsylvanica luciferases The C62, 86, and 284 residues are also absolutely 74 Genetic Engineering – Basics, New Applications and Responsibilities Origin C62 C82, C86 C146 C164 C260 ... wild-type luciferase and its mutant forms did not depend on the initial luciferase concentration The enzyme stabilization was only 76 Genetic Engineering – Basics, New Applications and Responsibilities...
Ngày tải lên: 22/06/2014, 03:20
Genetic Engineering Basics New Applications and Responsibilities Part 7 pptx
... Engineering – Basics, New Applications and Responsibilities characterized for transformation efficiency and lignin content (Table 4) Plants having antisense construct of C4H, CCR, CAD and POX showing ... one key approach to increasing agricultural production and reducing losses due to biotic and abiotic stresses in the field and in storage (Sairam and Prakash, 2005; Yuan et al., 2011) This chapter ... Engineering – Basics, New Applications and Responsibilities of pepper, tomato, rice (tomato), and transcription factors (tomato) have been field-tested Against plant viruses, single-stranded DNA binding...
Ngày tải lên: 22/06/2014, 03:20
Genetic Engineering Basics New Applications and Responsibilities Part 8 pot
... ages and lengths, untreated or pre-treated with acid or alkali, under various conditions of current and voltage as summarized in Table 134 Genetic Engineering – Basics, New Applications and Responsibilities ... (1998) 735-743 140 Genetic Engineering – Basics, New Applications and Responsibilities Cooley, J., Ford, T., and Christou, P (1995) Molecular and genetic characterisation of elite transgenic ... (Thompson et al., 1995) The method is simple and easy to adapt to new crops, but the transformation efficiencies are low, and the fibres must be handled with care since they pose a health risk...
Ngày tải lên: 22/06/2014, 03:20
Genetic Engineering Basics New Applications and Responsibilities Part 10 potx
... goat = CHGH, HCS (6 and 2) = Human chorionic somatomammotropin clones and 2, dog = CFGH and HGH (1 and 2) = cloned human GH and In the right gel lanes: cat (1 and 2) = GH and from cat; cow = ... milk production and a subsequent savings in maintenance, feeding, water, drugs, etc It also reduces the production of manure, and nitrogen from urine and methane (27) 177 Genetic Engineering and ... steps followed for the production and scaling, semipurification and bioassay of each of the recombinant hormones are shown 184 Genetic Engineering – Basics, New Applications and Responsibilities...
Ngày tải lên: 22/06/2014, 03:20
Genetic Engineering Basics New Applications and Responsibilities Part 15 doc
... mountainous highland region (north, east, and south) constituting 70% of the land area, and a western coastal lowland region that contains nearly all of the country's agricultural lands and is the ... demand, good prices and government subsidies for expanding the production base Official data on olive oil production show an output ranging between 6,400 Mt (Million ton) in bad harvest years and ... the Albanian olive production zone covers the entire coast from Saranda (South) to Shkodra (North) and inland river valleys in the districts of Peqin/Elbasan, Berat/Skrapar, and Tepelene/Permet...
Ngày tải lên: 22/06/2014, 03:20
Báo cáo hóa học: " Vector Quantization of Harmonic Magnitudes in Speech Coding Applications—A Survey and New Technique" pot
... used (5) and (6) to measure the average SD and the results are 4.43 dB in training and 4.37 dB in testing For MELP we used (7), (8), and (9); the average SD results are 3.32 dB in training and 3.31 ... (DCT), and is quantized using two codebooks: the transform or matrix codebook and the residual codebook, with the quantized vector given by the product of a matrix found from the first codebook and ... Kleijn and K K Paliwal, Speech Coding and Synthesis, Elsevier Science Publishers, Amsterdam, The Netherlands, 1995 [3] A Gersho and R M Gray, Vector Quantization and Signal Compression, Kluwer Academic,...
Ngày tải lên: 23/06/2014, 01:20
THEORY AND NEW APPLICATIONS OF SWARM INTELLIGENCE pot
... optimization algorithms (Kennedy and Ebarhart, 1995; Yang, 2008; Auger and Teytaud, 2010; Auger and Doerr, 2010; Blum and Roli, 2003; Neumann and Witt 2010; Parpinelli and Lopes, 2011) Good examples ... Metaheuristics, in: Handbook on Simulation (Eds Nelson and Henderson), Handbooks in Operation Reserch and Management Science VII, Elsevier, pp 633-654 (2006) [28] Parpinelli, R S., and Lopes, H S., New inspirations ... range in the search space and the optima values Figures 3, and present the fitness convergence along 10,000 iterations for the Rosenbrock, Rastrigin and 28 12 Theory and New Applications of Swarm...
Ngày tải lên: 26/06/2014, 23:20
GRID COMPUTING – TECHNOLOGY AND APPLICATIONS, WIDESPREAD COVERAGE AND NEW HORIZONS pot
... Grid technologies and boost related industry supply and demand Many chapters consider applications and case studies that provide useful information about challenges, pitfalls, and successful approaches ... Computing – Technology and Applications, Widespread Coverage andWill-be-set-by-IN-TECH New Horizons Sahai, A., Graupner, S., Machiraju, V and Moorsel, A 2003 ’Specifying and Monitoring Guarantees ... speeds and communication bandwidths The set of PEs is expressed as P = { P1 , P2 , , Pm }, 32 Grid Computing – Technology and Applications, Widespread Coverage andWill-be-set-by-IN-TECH New Horizons...
Ngày tải lên: 27/06/2014, 00:20
METHODOLOGIES, TOOLS AND NEW DEVELOPMENTS FOR E-LEARNING doc
... Tools and New Developments for E-Learning, Edited by Elvis Pontes, Anderson Silva, Adilson Guelfi and Sérgio Takeo Kofuji p cm ISBN 978-953-51-0029-4 Contents Preface IX Part Methodologies and ... Books, New York, NY Taylor, C (2005) It’s a Wiki, Wiki World Time 165(23): 40-42 Vanderwal, T., (2005) Explaining and Showing Broad and Narrow Folksonomies, http://www.vanderwal.net/random/entrysel.php?blog=1635 ... Tools and New Developments for E-Learning separate folder of a corresponding name and the similar structure The most important - and obligatory in each folder - files, are: mod_form.php and view.php...
Ngày tải lên: 27/06/2014, 05:20
NEW RESEARCH ON KNOWLEDGE MANAGEMENT APPLICATIONS AND LESSON LEARNED doc
... develop new products that meet market needs; (2) ability to apply appropriate process technologies to producing these new products; (3) ability to develop and adopt these new products and process ... share, productivity, debt ratios, and stock prices Ittner and Larcker (1997) differentiated between financial and non-financial measures of 10 New Research on Knowledge Management Applications and ... Implementation, and Profits (New York: Oxford University Press.) 20 New Research on Knowledge Management Applications and Lesson Learned Amin, A and Thrift, N (1995), 'Holding down the global', in A Amin and...
Ngày tải lên: 27/06/2014, 05:20
GENETIC ENGINEERING – BASICS, NEW APPLICATIONS AND RESPONSIBILITIES docx
... attB1 and attB2, attP1 and attP2, attL1 and attL2, and attR1 and attR2; a recombination reaction can occur only in the combinations of attB1 and attP1, attB2 and attP2, attL1 and attR1, or attL2 and ... leading strand and lagging strand are both formed when it is unwound The leading strand allows replication to occur continuously and therefore needs only one primer, however, the lagging strand is ... combined with several weak promoters (Yew et al., 1997) and Li and colleagues have further 18 Genetic Engineering – Basics, New Applications and Responsibilities demonstrated that adding an SV40...
Ngày tải lên: 28/06/2014, 15:20
NONDESTRUCTIVE TESTING METHODS AND NEW APPLICATIONS pdf
... Silva and Germano X de Padua Innovative Nondestructive Testing Systems and Applications 23 Chapter SQUID Based Nondestructive Evaluation 25 Nagendran Ramasamy and Madhukar Janawadkar Chapter Applications ... components, the online monitoring of manufacturing processes and products, and a wide array of medical applications that include dental and veterinary medicine This book will seek to introduce several ... used for training and certification of NDT personnel 12 a Nondestructive Testing Methods and New Applications Fatigue cracks For metal alloys, fatigue cracks are initiated and grown under controlled...
Ngày tải lên: 28/06/2014, 17:20