an emerging trend in tuberculosis drug development

... workers; and the extension of social insurance to rural–urban migrants” To avoid overcrowding in the major cities such as Beijing and Shanghai, the government is building infrastructure and rewarding ... Huang, Y 2005, ‘Urban Housing in China: Market Transition, Housing Mobility and Neighbourhood Change’, Housing Studies, Vol 21, No.5, 613-623, September 2006 Manquand, R 2004, ‘China’s peasants ... urban China has significantly influenced business opportunities for organizations doing business in China on both the supply and demand side The future economic growth of China is reliant on the...

Ngày tải lên: 27/06/2014, 23:20

... recognizing carcinoembryonic antigen into patients with metastatic colorectal cancer induced inflammatory colitis without mediating anti-tumor effects American Society of Gene and Cell Therapy 2010 annual ... Sgouros G, Junghans RP: Antibody therapies of cancer In Cancer Chemotherapy and Biotherapy: Principles and Practice Edited by: Chabner BA, Longo DL Lippincott, Wheeler and Wilkins, Philadelphia; ... Non-myeloblative induction of mixed hematopoietic chimerism: application to transplantation tolerance and hematologic malignancies in experimental and clinical studies Cancer Treat Res 2002, 110:79-99 Junghans...

Ngày tải lên: 18/06/2014, 16:20

... investigating the transcriptomes of Listeria grown in vitro in several conditions (including exponential and stationary phase, low O2, two temperatures), in vivo (in the intestine of germ-free animals), ... animals), and ex vivo in blood The wild-type Listeria strain EGD-e transcriptomes were compared with those of several isogenic mutants, including a prfA mutant, a sigma B mutant and an hfq mutant Hfq ... hydrolase absent from all L innocua strains analyzed and which enables bacterial persistence in the intestinal lumen and in deeper organs such as the liver [6] Current investigations are focused...

Ngày tải lên: 06/08/2014, 19:21

... increasing feed angle may be attributed to an increase in the initial band width An increase in the feed angle increases the first and second moments, which are related to the elution angle and ... 81 Mg2+-independent Neutral Sphingomyelinases 84 Alkaline Sphingomyelinase from the Intestinal Tract 85 Bacterial Sphingomyelinase-phospholipase C 85 Sphingomyelinase Mechanism 85 Binding of Magnesium ... Ions 85 Binding of Substrate 85 Mechanism of Catalysis 86 Sphingomyelinase Assay 88 Sphingomyelinase Inhibitors 89 Sphingomyelinase–Membrane Interactions 89 Lipid Effects on Sphingomyelinase Activity...

Ngày tải lên: 17/02/2014, 05:20

... Kunda J, Makasi CE, Mwaseba D, Range NS, Mfinanga GS: Perceptions of tuberculosis and treatment seeking behaviour in Ilala and Kinondoni Municipalities in Tanzania Tanzan J Health Res 2008, 10(2):89-94 ... treatment management and is also included in the guidelines to improve cure rates and compliance Further, as part of patient monitoring and follow up, microscopy is to be repeated at 2, and months ... dialogue, giving the patient a chance to ask questions, an important aspect in patient management that ensures patient understanding of disease and treatment The effects of non-dialogue counselling were...

Ngày tải lên: 06/03/2014, 04:20

... evident that protein trafficking into the inner nuclear membrane is an important mechanism regulating gene expression, transducing signals from the plasma membrane to the nucleus in response to various ... expression and human colon cancer development, because higher levels of RNF13 protein are detected in human colon cancer samples than in control samples Most intriguingly, microarray analysis of ... substrate binding or to be involved in protein–protein interactions [7–9] The RING region is a C3H2C3 type and exerts E3 activity [5,6] Bioinformatics predictions and experimental evidence indicate...

Ngày tải lên: 22/03/2014, 17:20

... products and services that support continue to improve their capabilities Knowledge Management: An Emerging Discipline Rooted in a Long History and can participate in creating and supporting innovations ... relevant support information and knowledge, making preliminary sense of the situation, and locating and presenting suggestions for how it should be handled Knowledge Management: An Emerging Discipline ... concepts inherited from prior generations References Austin, Robert D (1996) Measuring and Managing Performance in Organizations New York: Dorset House Bechara, Antoine; Damasio, Hanna; Tranel, Daniel;...

Ngày tải lên: 23/03/2014, 23:21

... patient continues being a center of infection in the community and can lead to the dissemination of resistant forms The risk factors for the development of resistance include inhabiting endemic ... whole interdisciplinary team, an intervention program was established, using strength and resistance training for upper and lower limbs, education, and techniques of energy conservation In this ... Multi -drug resistance to antituberculous medicine (defined as the resistance, at least, to isoniazide and rifampicine) is widely accepted as a threat against the control of tuberculosis (Tb) in...

Ngày tải lên: 29/03/2014, 03:20

... path to investigations of synchronous gating and the role of oscillations in generating and maintaining a stable phenotype Are equal numbers of genes transcribed at all points in the cycle? In their ... reported an oscillation in oxygen consumption in the 40-min range The CEN.PK strain cells in our hands have a period that varies, quantally between and h The report from Tu et al [16] describes an ... determining such relationships If by treating cells with a drug such as phenelzine and following the changes that occur in the surface as the system responds, we have at least the beginnings of...

Ngày tải lên: 30/03/2014, 04:20

... The information to be obtained includes rubber production information in the border areas in China, rubber trading and marketing in the Lao-Chinese border, and current and future demand and supply ... growth in China’s demand for rubber is influencing the Chinese investment in rubber planting in northern of the Lao PDR and is very likely influencing the Vietnamese proposals for rubber plantation ... rapidly in Lao PDR, the Government and different international organisations, including institutional arrangements, planning, policy, regulation and the information, are paying great attention and...

Ngày tải lên: 31/03/2014, 09:21

... Combinatorial Mixture Screening / 103 In Vivo Drug Screening / 106 Pharmacokinetics / 109 In Vitro Drug Screening / 115 Metabolic Stability Screening / 118 Membrane Permeability / 119 Drug- Drug Interaction ... of academic, instrument manufacture, and industry 10 INTRODUCTION interests However, the current industry trends highlight the tremendous challenge of drug development and an expanding need for ... establishing efficacy, determining the effective dose range, and obtaining safety and tolerability data In phase II, the dose and dosing interval to be employed in the patient population and the...

Ngày tải lên: 11/04/2014, 07:01

... wisely, eg in training field veterinarians in AI diagnosis, the training should be general to cover all diseases including FMD, CSF and other diseases of importance in Vietnam Also in improving AI ... of the right vaccine and improving the efficacy of vaccination 5.3 Capacity Building Training and education of field veterinarians in disease prevention, disease investigation and sample collection ... antigen and antibody and the standardisation of reagents Training was carried out under a quality system emphasizing the importance of Quality Assurance in the laboratory focusing on test maintenance,...

Ngày tải lên: 22/06/2014, 12:20

... molecular and sequencing techniques Training and education of field veterinarians in sample and data collection showed an impact with an increase in quality and numbers of samples collected and submitted ... vital role in making Vietnam more economically competitive Improved animal health will lead to an increase in rural productivity though increased animal production and indirectly in increased ... developing an understanding of FMD epidemiology in Vietnam The field studies and serosurveillance approaches were designed and planned in conjunction with DAH to provide the maximum necessary information...

Ngày tải lên: 22/06/2014, 12:20

... molecular and sequencing techniques Training and education of field veterinarians in sample and data collection showed an impact with an increase in quality and numbers of samples collected and submitted ... supplying training for AI Training in data analysis by DAH staff is also an area that needs further input 6.2 Options The government of Vietnam is looking at increasing the support to DAH and has increased ... FMD in pigs in the province in that year, which would increase willingness of farmers to present piglets for vaccination and sampling and enhanced awareness and enthusiasm on the part of veterinarians...

Ngày tải lên: 22/06/2014, 12:20

... greatly assisted in the training of epidemiologists and field veterinarians in FMD serosurveillance, outbreak control and disease investigation including vaccine failure During the course of ... RAHC-HCMC and NCDCHanoi to coordinate training and meetings with field veterinarians in provinces where fields studies are to be carried out First 3-6 months year Workshop meetings held & Training ... resulted in limited sero-surveillance in Northern and Central provinces Initial project implementation in the field highlighted the need for further training of field veterinarians in disease investigation...

Ngày tải lên: 22/06/2014, 12:20

... supplying training for AI Training in data analysis by DAH staff is also an area that needs further input 10 7.2 Options The government of Vietnam is looking at increasing the support to DAH and ... out surveillance and testing 1.1 Train field veterinary staff in outbreak investigation for the investigation of cases of FMD on farms, including record keeping, sampling strategies and data collection ... Determine the efficacy of the FMD vaccine in protecting against FMD isolates circulating in Vietnam Comparison of FMD genotypes to vaccine Results of sero-surveillance Hold information and training...

Ngày tải lên: 22/06/2014, 12:20

... supplying training for AI Training in data analysis by DAH staff is also an area that needs further input 7.2 Options The government of Vietnam is looking at increasing the support to DAH and has increased ... 02 provinces (Quang Ninh and Lang Son) , total 480 sera samples 2.2.2 RAHC-Da Nang : 02 provinces (Kontum and Quang Nam) , total 480 sera samples 2.2.3 RAHC-Can Tho : 02 provinces (An Giang, Kien ... through the training programs and also through the achievements so far in the project in understanding FMD in Vietnam FMD is a disease on importance in Vietnam and this has put our project into the...

Ngày tải lên: 22/06/2014, 12:20

... Relevant to Multinationals Destan Kandemir, Daekwan Kim, and S Tamer Cavusgil 121 International Joint Venture Control: An Integrated Framework Yan Zhang and Haiyang Li 147 An Analysis of Joint ... Activities in Southeast Asia Daniel C Indro and Malika Richards 171 National Culture in China and Multinationals’ Performance Ji Li 195 Entering Emerging Markets: Ignorance and Discovery Jan Johanson and ... Global Firms and Emerging Markets in an Age of Anxiety Global Firms and Emerging Markets in an Age of Anxiety Edited by S Benjamin Prasad and Pervez N Ghauri Library of Congress Cataloging -in- Publication...

Ngày tải lên: 28/06/2014, 00:20

... Relevant to Multinationals Destan Kandemir, Daekwan Kim, and S Tamer Cavusgil 121 International Joint Venture Control: An Integrated Framework Yan Zhang and Haiyang Li 147 An Analysis of Joint ... Activities in Southeast Asia Daniel C Indro and Malika Richards 171 National Culture in China and Multinationals’ Performance Ji Li 195 Entering Emerging Markets: Ignorance and Discovery Jan Johanson and ... Global Firms and Emerging Markets in an Age of Anxiety Global Firms and Emerging Markets in an Age of Anxiety Edited by S Benjamin Prasad and Pervez N Ghauri Library of Congress Cataloging -in- Publication...

Ngày tải lên: 28/06/2014, 22:20

... of Finance and Accountancy INTRODUCTION Recent empirical research suggests a growing interest in the financial management practices among businesses in less developed countries and emerging markets ... contrasting capital structure determinants across countries can be seen in Wald, 1999, for instance, who compares the financing behavior of firms in the U.S., Germany, France, the U.K., and Japan, and ... with that of firms in emerging markets such as India, Jordan, and Pakistan, so as to study the impact of the differences in institutional setting and degree of financial market development on corporate...

Ngày tải lên: 12/07/2014, 19:09