an aggressive and violent complex

... Trauma and Orthopaedics, North Middlesex University Hospital, Sterling Way, London N18 1QX, UK Authors’ contributions ST, AL and MB managed and operated the patient HDA, AL and MB wrote the manuscript ... Resection-arthrodesis for malignant and potentially malignant lesions about the knee using an intramedullary rod and local bone grafts J Bone Joint Surg [Am] 1977, 59(2):223-36 31 Canadell J, San-Julian M, Cara J, ... AL and MB wrote the manuscript ST, JS and ZR assisted with the literature review and manuscript preparation All authors have read and approved the final manuscript Competing interests No competing...

Ngày tải lên: 20/06/2014, 04:20

... statistical analysis and Dr Kwang-soo Lyoo and Mrs Sook Shin for technical assistance References Bianchi, A T J and van, P J der Heijden Antigen presenting cells and B-cells in the pig Vet Immunol Immunopathol ... differentiation antigen, and cytokines in animal and birds Monographs in Animal Immunol., VA:BAR-1 AB Inc., Blacksburg, 1990 Fenner, F J., E P J Gibbs, F A Murphy, R Rott, M J Studdert, and D O White ... neutralizing antibody titers in swine fever Vet Microbiol 1988, 16, 123-128 Timoney, J F., J H Gillespie, F W Scott, and J E Barlough Hagan and Brunners microbiology and infectious diseases of domestic animals...

Ngày tải lên: 07/08/2014, 14:23

... The study was funded from the Norwegian University of Science and Technology and St Olavs University Hospital The authors thank Berit Hansen and Gaute Strand for conducting the inter-rater pre ... threatening, and attacking objects [20] It has demonstrated satisfactory properties in forensic and acute settings [21,37], and now in a PICU setting The instrument is short, practical and easy to ... data PANSS total, PANSS subscales, GAF-S, medication, side effects, “frequency of testing out and pushing limits”, “intensity of testing out and pushing limits”, “need to set limits”, gender and...

Ngày tải lên: 11/08/2014, 16:23

... Adhikari and S Scheiner p*(CO) interaction, as many of the other structures Another minimum, 0.2 kcal mol1 higher than the first, adds another pair of charge transfers, both into the SS s* antibonding ... stronger than NHãããS Indeed, the latter H-bond is strengthened in CH3SCH3 and CH3SSCH3, thus invalidating any general statement about the relative strengths of SHãããO and NHãããS On the other hand, ... NHãããS, and CHãããO H-bond energies of 4.12, 3.95, and 3.52 kcal mol1, resame H-bonds are both supplemented by charge transfer from the CO p orbital, so can be termed CHãããp spectively Charge transfer...

Ngày tải lên: 16/12/2012, 15:21

... nổ xong Lưu ý: - Đường bột dễ tan bơ Nếu dùng đường hạt nên làm tan đường bơ trước, không làm tan đun bơ bếp bơ đường nhanh cháy, dễ tạo mùi khét mà đường chưa tan hết 15 Dorayaki - Bánh rán Doraemon ... rau luộc với cách dùng sốt bơ chanh Nguyên liệu: - Rau xanh (tùy chọn loại: măng tây, đỗ xanh, đậu đũa, đậu Hà Lan, đậu ngọt) - Muối - Sốt bơ: tỉ lệ tbs nước chanh vàng + 2.5 tbs bơ Cách làm: ... gà chín mềm Lưu ý: - Nên dùng tiêu nguyên hạt, làm đem rang hạt tiêu ăn thêm thơm ngon Rau xanh rưới sốt bơ chanh Món rau luộc cần thời gian để chế biến, ăn rau lại có lợi cho sức khỏe Bạn tạo...

Ngày tải lên: 28/08/2013, 18:20

... VIETNAM NATIONAL UNIVERSITY - HANOI COLLEGE OF FOREIGN LANGUAGES POST-GRADUATE DEPARTMENT DƯƠNG THỊ HỒNG AN AN EVALUATION AND APPLICATION OF SOME MULTIMEDIA PRESENTATION SOFTWARE ... thiết kế giảng môn tiếng Anh Khoa Công nghệ thông tin - Đại học Thái Nguyên) MINOR PROGRAMME THESIS ENGLISH TEACHING METHODOLOGY CODE: 60.14.10 Supervisor : DO TUAN MINH, PhD HANOI - 2009 ...

Ngày tải lên: 07/09/2013, 13:08

... However, some and any need not stand directly before the noun Sometimes, the noun appears somewhere before some or any and is not repeated So if you are not sure ... positive clauses But after never, without, hardly, we use any Example: We never go anywhere She did her homework without any help There’s hardly anyone here ... a noun in the sentence that you can place after some Example: I not have to buy bread Rachel has already bought some [bread] Exceptions Positive Clauses with Any We usually use some in positive...

Ngày tải lên: 04/12/2013, 20:11

... situation and subject matter - Organize their thoughts in a meaningful and logical sequence - Use language as a means of expressing values and judgments - Use the language quickly and confidently ... interesting and relevant to their age and level of ability, where the learning goal was challenging yet manageable and clear, and where the atmosphere was supportive and nonthreatening, teachers can make ... change from Grammar -Translation Method by the use of the target language as a means of instruction and communication in the language classroom, and by the avoidance of the use of the first language...

Ngày tải lên: 18/12/2013, 10:08

... Ngoc Anh* Development and Policies Research Center No 216 Tran Quang Khai, Hanoi, Vietnam http://www.depocen.org Nguyen Thang Center for Analysis and Forecasting No1 Lieu Giai Street, Hanoi, ... useful comments and suggestions Doan Quang Hung and Nguyen Van Anh provided excellent research assistance in collecting the data The authors alone are responsible for all errors and omissions FOREIGN ... percent and the register capital 20 percent Table FDI by country of origin, 1988-2006 No 10 Countries and Territories Taiwan Singapore Korea Japan Hong Kong British Virgin Islands Netherlands France...

Ngày tải lên: 16/01/2014, 01:28

... death and proliferation enable a mutant clone with a survival or reproductive advantage to expand The presence of proliferating and apoptotic cells in neoplasms implies that clones can expand and ... cartography of neoplastic fitness landscapes Conclusions and future directions To understand cancer, we need to understand and measure the population dynamics and evolutionary parameters of neoplasms ... leukoplakia161,162 and ulcerative colitis163,164 Serial biopsies can also be obtained during randomized trials to prevent or treat some cancers, for example, gastric165 and prostate cancer166 A randomized...

Ngày tải lên: 15/02/2014, 05:20

... ternary complex [12] Both bsSHMT and E53QbsSHMT ternary complexes were dialyzed against buffer (50 mm potassium phosphate pH 7.4 containing mm EDTA and mm 2-mercaptoethanol) devoid of Gly and FTHF and ... the mutant and bsSHMT-Ser complexes are similar except for OE1 and NE2 atoms No significant changes in the conformation of residues Y60, Y61 and PLP orientation are observed in the mutant with ... Biophysics Unit, Indian Institute of Science, supported by the Department of Science and Technology and DBT We thank Babu and James for their help during data collection VR and BSB thank the Council...

Ngày tải lên: 18/02/2014, 16:20

... Drive, Garland, Texas, 75043 He paused Garland, Texas Garland, Garland, Texas? Who did he know in Garland, Texas, on Mayflower Drive? He set down the magazine and looked up on his wall The fan letters! ... Carmack, the graphics guru and resident Whiz Kid; Romero, the multitalented programmer and company cheerleader; Adrian, the artist and dark visionary; and Tom, game designer and comic book surrealist ... skilled and driven than the co-creators of Doom and Quake, John Carmack and John Romero, or, as they were known, the Two Johns For a new generation, Carmack and Romero personified an American dream:...

Ngày tải lên: 22/02/2014, 21:33

... has a b-sandwich architecture and is composed of two six-stranded antiparallel b-sheets In both b-sheets the sixth strand is located between strands and Although the antiparallel pattern of both ... loops and the loops between b-strand 2–3 of each blade The second funnel on the opposite side of the cylinder is shallower and is formed by loops 2–3 and 3–4 connecting antiparallel b-strands ... extended, and two (loop 2–3 in blade II and loop 2–3 in blade V) have helical turns on the top The latter loop is greatly extended and 1732 also forms an additional b-strand interacting with strand...

Ngày tải lên: 06/03/2014, 00:21

... financial sector policies and legal enforcement, financial sector regulation and supervision, and economic and social policies Chapter 2–The Target Market and Impact Analysis looks at the demand ... understanding among all stakeholders Part II Designing and Monitoring Financial Products and Services Part III Measuring Performance and Managing Viability Organization of the Book The handbook ... savings banks, and credit unions funded their loan portfolios with client and member deposits and commercial loans I NGOs offered the smallest loan sizes and relatively more social services than banks,...

Ngày tải lên: 06/03/2014, 08:21

... human, 1EFV [1]; W3A1, 1O96 [3] a- and b-ETF chains are shown as magenta and blue cartoons FAD and AMP are shown as yellow and orange sticks, respectively Conserved Leub195 ⁄ 194 for human and ... domains II and III in human (A) and Methylophilus methylotrophus W3A1 (B) ETFs PDB codes: human, 1EFV [1]; W3A1, 1O96 [3] a- and b-ETF chains are shown as magenta and blue cartoons and sticks ... I and III are composed of a core of a seven-stranded parallel b-sheet, flanked by solvent-exposed a-helices These domains also contain a three-stranded antiparallel b-sheet with a fourth strand...

Ngày tải lên: 07/03/2014, 05:20

... both to understand how HGF ⁄ SF interaction with Met leads to receptor dimerization and signal transduction and to design Met inhibitors as anticancer drugs [15] Mass spectrometric analysis of digests ... either simultaneously or in any desired order; and (b) in and out filtering of defined reaction products Our aim is to establish general, rapid and relatively simple procedures for the analysis of ... distance of 11.4 A which can be spanned by the BS cross-linker (Fig 6) Another candidate cross-linked peptide pair connecting K44 and K91 was assigned by virtualmslab Tandem MS data allowed neither...

Ngày tải lên: 07/03/2014, 12:20

... transmembrane segment) [17] and I486M (1st extracellular loop) [3], named I486M/P639S, and the double mutant receptor (containing an activating together with an inactivating TSHr mutation) P639S and ... conjugated with fluorescin 5-isothiocyanate and PI Fluorescence emission of fluorescin 5-isothiocyanate and PI from single cells were separated and measured using the standard optics of the FACSort The ... Dickinson and Co.) was used to acquire and analyze data A minimum of at least 10 000 cells was analyzed Computation of specific constitutive activity (SCA) and relative SCA (RSCA) Given that the transfection...

Ngày tải lên: 08/03/2014, 08:20

... Apaf-1 and p53, and simultaneous overexpression of the antiapoptotic proteins Hsp70, Bcl-2 and Bcl-xL, resulting in tumor-specific suppression of apoptosis and enhancement of the malignance and therapy ... caspase 3, c-IAP-2 and AFP To study further the interaction between AFP, cIAP-2 and caspases and 3, we precipitated pure recombinant active caspases and (His-tagged) with nickel resin and then incubated ... using 15% polyacrylamide and then analysed by Western blot using the cyt-c antibody 7H8.2C12, cyt-c oxidase subunit II antibody (Molecular Probes), and b-actin antibody and ECL as described above...

Ngày tải lên: 08/03/2014, 08:20

... business! Handmade cards Buying something that has been made by hand has always been a special experience Handmade chocolates, shoes and furniture have always had a special cachet and the same can be ... correct and the bone folder will give a good finish to the fold Sewing tools Stitching produces beautiful results on handmade cards, and it can be done either by hand or machine If stitching by hand ... the excess and return to the jar Then use the heat gun to melt the powder and create a raised deign HANDMADE CARDS / 19 Greetings If you are not good at lettering and don’t want to hand write...

Ngày tải lên: 10/03/2014, 20:37

... estrogen and androgen, because use of antagonists to androgen and estrogen receptors (flutamide and ICI 182,780, respectively), and letrozol, an inhibitor of the aromatase responsible for converting androgen ... 6) On the other hand, CASKI and HeLa cells showed higher early and late apoptosis than C33A cells (Table 2) These results indicate that DHEA can induce early and late apoptosis and also necrosis ... order to assess this, antagonists to androgen and estrogen receptors (flutamide and ICI 182,780, respectively), and an inhibitor of the aromatase responsible for conversion of androgen to estrogen...

Ngày tải lên: 16/03/2014, 00:20