... Chapter 101 . Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 1) Harrison's Internal Medicine > Chapter 101 . Hemolytic Anemias and Anemia Due to Acute Blood Loss Definitions ... classification of anemias comprises three groups: decreased production of red cells, increased destruction of red cells, and acute blood loss. Red cell destruction and acute loss, both associated ... of anemia in these two groups of patients are quite different, and they will be considered separately. Hemolytic Anemias Anemias due to increased destruction of red cells, or hemolytic anemias...
Ngày tải lên: 07/07/2014, 04:20
... often associated with hemosiderinuria and an Chapter 101 . Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 2) Table 101 -2 General Features of Hemolytic Disorders General ... gradual loss of cellular organelles and of biosynthetic abilities. In the end the erythroid cell undergoes a process that has features of apoptosis, including nuclear pyknosis and actual loss ... reticulocytes is associated with an increased mean corpuscular volume (MCV) in the blood count. On the blood smear this is reflected in the presence of macrocytes; there is also polychromasia...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 3) pptx
... Chapter 101 . Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 3) Figure 101 -1 cause considerable iron loss, needing replacement. With chronic ... except there is no anemia. This notion is important from the diagnostic point of view, because a patient with a hemolytic condition, even an inherited one, may present without anemia. It is also ... "decompensated"—i.e., anemia may suddenly appear—in certain circumstances—for instance, pregnancy, folate deficiency, renal failure interfering with adequate EPO production, or an acute infection...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 5) ppt
... (with the patient being homozygous). Figure 101 -3 Chapter 101 . Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 5) Hemolytic Anemias Due to Abnormalities of the Membrane- Cytoskeleton ... as an inherited form of HA associated with the presence of spherocytes in the peripheral blood (Fig. 101 -3A). In addition, in vitro studies revealed that the red cells were abnormally susceptible ... these proteins are heavily glycosylated, and they carry antigenic determinants that correspond to blood groups. Underneath the membrane, and tangential to it, is a network of other proteins that...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 6) doc
... Chapter 101 . Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 6) Peripheral blood smear from patients with membrane-cytoskeleton abnormalities. ... Pravan (eds): Molecular Hematology, 2d edition. Oxford, Blackwell, 2005; with permission.] Table 101 -3 Inherited Diseases of the Red Cell Membrane- Cytoskeleton Gene Chromoso mal Location Protei n...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 7) docx
... Chapter 101 . Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 7) Clinical Presentation and Diagnosis The spectrum of ... present in infancy with severe anemia, whereas mild cases may present in young adults or even later in life. In women, HS is sometimes first diagnosed when anemia is investigated during pregnancy. ... conditions (e.g., infection) cause may have nearly 100 % elliptocytes, whereas in severe cases, all sorts of bizarre poikilocytes may predominate (Fig. 101 -3B, C). Clinical features and recommended...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 8) pdf
... Chapter 101 . Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 8) Abnormalities of the Glycolytic Pathway (Fig. 101 -1) Since red cells, in the course ... pathway are all inherited and all rare (Table 101 -4). Among them, deficiency of pyruvate kinase (PK) is the least rare, with an estimated prevalence of 1 :10, 000. The clinical picture is that of an ... usually associated with a very high reticulocytosis. The anemia is of variable severity; sometimes it is so severe as to require regular blood transfusions; sometimes it is mild, bordering on...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 9) ppsx
... require exchange transfusion; if the anemia is less severe, it may present later in life or may even remain asymptomatic and be detected incidentally when a blood count is done for unrelated ... the redox metabolism of all aerobic cells (Fig. 101 -4). In red cells, its Among the mutations, those underlying chronic nonspherocytic hemolytic anemia (CNSHA; see below) are a discrete subset. ... or both. The diagnosis of HA is usually not difficult, thanks to the triad of normo-macrocytic anemia, reticulocytosis, and hyperbilirubinemia. Enzymopathies should be considered in the differential...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 10) pps
... comorbidity, full recovery from acute HA associated with G6PD deficiency is the rule. Chapter 101 . Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 10) Epidemiology G6PD deficiency ... hemolysis. The most serious threat from acute HA in adults is the development of acute renal failure (exceedingly rare in children). Once the threat of acute anemia is over, and in the absence of ... parts of the world (Africa, Southern Europe, the Middle East, Southeast Asia, and Oceania) (Fig. 101 -5) and wherever people from those areas have migrated; a conservative estimate is that at least...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 11) doc
... Favism Acute Destruc tion of older fraction of G6PD- deficient red G6PD assay Triggere d by ingestion of large dish of fava beans; but t rigger can be Chapter 101 . Hemolytic Anemias and Anemia ... beans; but t rigger can be Chapter 101 . Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 11) Table 101 - 5 Drugs that Carry Risk of Clinical Hemolysis in Persons with G6PD Deficiency ... Clostridium perfringens be responsible Microangio pathic Acute or chronic Red cell fragmentation Red cell morphology on blood smear Different causes ranging from endothelial damage...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 12) doc
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 13) pptx
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 14) pps
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 15) potx
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 16) ppt
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 17) potx
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báo cáo hóa học:" Use of Tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement" ppt
... aggravate post-operative haemorrhage [8 -10] . The pro blem of excessive blood loss i s further highl ighted in cases of simultaneous bilateral total knee replacement where blood loss i s usually twice that ... interests. Received: 13 October 2 010 Accepted: 21 May 2011 Published: 21 May 2011 References 1. Cushner FD, F R: Blood loss in total knee arthroplasty. Clin Orth 1991, 269:98 -101 . 2. Fragen RJ, S S, Wixson ... 76:1545-50. 5. Mylod AG, F M, Muser DE, Parsons JR: Perioperative blood loss associated with total knee arthroplasty. J Bone Joint Surg(Am) 1990, 72 :101 0-2. 6. Fauno P, S O, Rehnberg V, et al: Prophylaxis...
Ngày tải lên: 20/06/2014, 04:20
báo cáo hóa học:" Use of Tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement" pdf
... aggravate post-operative haemorrhage [8 -10] . The pro blem of excessive blood loss i s further highl ighted in cases of simultaneous bilateral total knee replacement where blood loss i s usually twice that ... interests. Received: 13 October 2 010 Accepted: 21 May 2011 Published: 21 May 2011 References 1. Cushner FD, F R: Blood loss in total knee arthroplasty. Clin Orth 1991, 269:98 -101 . 2. Fragen RJ, S S, Wixson ... 76:1545-50. 5. Mylod AG, F M, Muser DE, Parsons JR: Perioperative blood loss associated with total knee arthroplasty. J Bone Joint Surg(Am) 1990, 72 :101 0-2. 6. Fauno P, S O, Rehnberg V, et al: Prophylaxis...
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