acute blood loss anemia

... Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 1) Harrison's Internal Medicine > Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss Definitions A finite life ... classification of anemias comprises three groups: decreased production of red cells, increased destruction of red cells, and acute blood loss. Red cell destruction and acute loss, both associated ... of anemia in these two groups of patients are quite different, and they will be considered separately. Hemolytic Anemias Anemias due to increased destruction of red cells, or hemolytic anemias...

Ngày tải lên: 07/07/2014, 04:20

... hemoglobinuria, often associated with hemosiderinuria and an Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 2) Table 101-2 General Features of Hemolytic Disorders General ... gradual loss of cellular organelles and of biosynthetic abilities. In the end the erythroid cell undergoes a process that has features of apoptosis, including nuclear pyknosis and actual loss ... reticulocytes is associated with an increased mean corpuscular volume (MCV) in the blood count. On the blood smear this is reflected in the presence of macrocytes; there is also polychromasia...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 3) Figure 101-1 cause considerable iron loss, needing replacement. With chronic extravascular ... except there is no anemia. This notion is important from the diagnostic point of view, because a patient with a hemolytic condition, even an inherited one, may present without anemia. It is also ... "decompensated"—i.e., anemia may suddenly appear—in certain circumstances—for instance, pregnancy, folate deficiency, renal failure interfering with adequate EPO production, or an acute infection...

Ngày tải lên: 07/07/2014, 04:20

... being homozygous). Figure 101-3 Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 5) Hemolytic Anemias Due to Abnormalities of the Membrane- Cytoskeleton Complex ... these proteins are heavily glycosylated, and they carry antigenic determinants that correspond to blood groups. Underneath the membrane, and tangential to it, is a network of other proteins that ... thus diseases of the membrane-cytoskeleton complex belong to the category of inherited hemolytic anemias. Before the red cells lyse, they often exhibit more or less specific morphologic changes...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 6) Peripheral blood smear from patients with membrane-cytoskeleton abnormalities....

Ngày tải lên: 07/07/2014, 04:20

... Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 7) Clinical Presentation and Diagnosis The spectrum of clinical ... present in infancy with severe anemia, whereas mild cases may present in young adults or even later in life. In women, HS is sometimes first diagnosed when anemia is investigated during pregnancy. ... which, in its first approximation, has two important functions: (1) to provide decompensation. The anemia is usually normocytic, with the characteristic morphology that gives the disease its name....

Ngày tải lên: 07/07/2014, 04:20

... Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 8) Abnormalities of the Glycolytic Pathway (Fig. 101-1) Since ... usually associated with a very high reticulocytosis. The anemia is of variable severity; sometimes it is so severe as to require regular blood transfusions; sometimes it is mild, bordering on ... instance, in a woman during her first pregnancy, when the anemia may get worse. In part the delay in diagnosis is due to the fact that the anemia is remarkably well- tolerated because the metabolic...

Ngày tải lên: 07/07/2014, 04:20

... require exchange transfusion; if the anemia is less severe, it may present later in life or may even remain asymptomatic and be detected incidentally when a blood count is done for unrelated ... or both. The diagnosis of HA is usually not difficult, thanks to the triad of normo-macrocytic anemia, reticulocytosis, and hyperbilirubinemia. Enzymopathies should be considered in the differential ... 101-4). In red cells, its Among the mutations, those underlying chronic nonspherocytic hemolytic anemia (CNSHA; see below) are a discrete subset. This much more severe clinical phenotype can be...

Ngày tải lên: 07/07/2014, 04:20

... of comorbidity, full recovery from acute HA associated with G6PD deficiency is the rule. Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 10) Epidemiology G6PD ... hemolysis. The most serious threat from acute HA in adults is the development of acute renal failure (exceedingly rare in children). Once the threat of acute anemia is over, and in the absence of ... of them have an increased risk of developing neonatal jaundice (NNJ) and a risk of developing acute HA when challenged by a number of oxidative agents. NNJ related to G6PD deficiency is very...

Ngày tải lên: 07/07/2014, 04:20

... Favism Acute Destruc tion of older fraction of G6PD- deficient red G6PD assay Triggere d by ingestion of large dish of fava beans; but t rigger can be Chapter 101. Hemolytic Anemias and Anemia ... of fava beans; but t rigger can be Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 11) Table 101- 5 Drugs that Carry Risk of Clinical Hemolysis in Persons with ... Clostridium perfringens be responsible Microangio pathic Acute or chronic Red cell fragmentation Red cell morphology on blood smear Different causes ranging from endothelial damage...

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

... haemorrhage [8-10]. The pro blem of excessive blood loss i s further highl ighted in cases of simultaneous bilateral total knee replacement where blood loss i s usually twice that of a unilateral ... reduces perioperative blood loss associated with total knee arthroplasty. Br J Anesth 1995, 74:534-7. 22. Benoni G, G H: Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion ... requirement of blood transfusion after knee replacement. Introduction Total knee replacement is a frequently done procedure in modern day practice of any Orthopedics unit. Limit- ing blood loss both...

Ngày tải lên: 20/06/2014, 04:20

... order to reduce post- operative blood loss [16-19]. The use of tranexamic acid in orthopedic surgery has also shown promising results. It radically reduced both blood loss and the amount of allogenic ... reduces perioperative blood loss associated with total knee arthroplasty. Br J Anesth 1995, 74:534-7. 22. Benoni G, G H: Fibrinolytic inhibition with tranexamic acid reduces blood loss and blood transfusion ... haemorrhage [8-10]. The pro blem of excessive blood loss i s further highl ighted in cases of simultaneous bilateral total knee replacement where blood loss i s usually twice that of a unilateral...

Ngày tải lên: 20/06/2014, 07:20

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