... Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 1) Harrison's Internal Medicine > Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss Definitions A finite life ... classification of anemias comprises three groups: decreased production of red cells, increased destruction of red cells, and acute blood loss. Red cell destruction and acute loss, both associated ... production defects are discussed in Chaps. 98 , 99 , and 100. Physical loss of red cells from the bloodstream—which in most cases also means physical loss from the body—is fundamentally different...
Ngày tải lên: 07/07/2014, 04:20
... hemoglobinuria, often associated with hemosiderinuria and an Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 2) Table 101-2 General Features of Hemolytic Disorders General ... gradual loss of cellular organelles and of biosynthetic abilities. In the end the erythroid cell undergoes a process that has features of apoptosis, including nuclear pyknosis and actual loss ... reticulocytes is associated with an increased mean corpuscular volume (MCV) in the blood count. On the blood smear this is reflected in the presence of macrocytes; there is also polychromasia...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 3) pptx
... Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 3) Figure 101-1 cause considerable iron loss, needing replacement. With chronic extravascular ... except there is no anemia. This notion is important from the diagnostic point of view, because a patient with a hemolytic condition, even an inherited one, may present without anemia. It is also ... "decompensated"—i.e., anemia may suddenly appear—in certain circumstances—for instance, pregnancy, folate deficiency, renal failure interfering with adequate EPO production, or an acute infection...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 5) ppt
... being homozygous). Figure 101-3 Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 5) Hemolytic Anemias Due to Abnormalities of the Membrane- Cytoskeleton Complex ... common type of hemolytic anemia, with an estimated frequency of at least 1 in 5000. Its identification is credited to Minkowksy and Chauffard, who at the end of the 19th century reported families ... thus diseases of the membrane-cytoskeleton complex belong to the category of inherited hemolytic anemias. Before the red cells lyse, they often exhibit more or less specific morphologic changes...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 6) doc
... Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 6) Peripheral blood smear from patients with membrane-cytoskeleton abnormalities. ... ~25% of HS. Southea st Asian ovalocytosis (dominant) Polymorp hic mutation (deletion of 9 amino acids); clinically asymptomatic; protective against Plasmodium falcipa rum. EPB41 ...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 7) docx
... Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 7) Clinical Presentation and Diagnosis The spectrum of clinical ... present in infancy with severe anemia, whereas mild cases may present in young adults or even later in life. In women, HS is sometimes first diagnosed when anemia is investigated during pregnancy. ... which, in its first approximation, has two important functions: (1) to provide decompensation. The anemia is usually normocytic, with the characteristic morphology that gives the disease its name....
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 8) pdf
... Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 8) Abnormalities of the Glycolytic Pathway (Fig. 101-1) Since ... usually associated with a very high reticulocytosis. The anemia is of variable severity; sometimes it is so severe as to require regular blood transfusions; sometimes it is mild, bordering on ... instance, in a woman during her first pregnancy, when the anemia may get worse. In part the delay in diagnosis is due to the fact that the anemia is remarkably well- tolerated because the metabolic...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 9) ppsx
... require exchange transfusion; if the anemia is less severe, it may present later in life or may even remain asymptomatic and be detected incidentally when a blood count is done for unrelated ... or both. The diagnosis of HA is usually not difficult, thanks to the triad of normo-macrocytic anemia, reticulocytosis, and hyperbilirubinemia. Enzymopathies should be considered in the differential ... 101-4). In red cells, its Among the mutations, those underlying chronic nonspherocytic hemolytic anemia (CNSHA; see below) are a discrete subset. This much more severe clinical phenotype can be...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 10) pps
... of comorbidity, full recovery from acute HA associated with G6PD deficiency is the rule. Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 10) Epidemiology G6PD ... hemolysis. The most serious threat from acute HA in adults is the development of acute renal failure (exceedingly rare in children). Once the threat of acute anemia is over, and in the absence of ... of them have an increased risk of developing neonatal jaundice (NNJ) and a risk of developing acute HA when challenged by a number of oxidative agents. NNJ related to G6PD deficiency is very...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 11) doc
... Favism Acute Destruc tion of older fraction of G6PD- deficient red G6PD assay Triggere d by ingestion of large dish of fava beans; but t rigger can be Chapter 101. Hemolytic Anemias and Anemia ... of fava beans; but t rigger can be Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 11) Table 101- 5 Drugs that Carry Risk of Clinical Hemolysis in Persons with ... Clostridium perfringens be responsible Microangio pathic Acute or chronic Red cell fragmentation Red cell morphology on blood smear Different causes ranging from endothelial damage...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 12) doc
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 13) pptx
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 14) pps
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 15) potx
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 16) ppt
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 17) potx
Ngày tải lên: 07/07/2014, 04:20
báo cáo hóa học:" Use of Tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement" ppt
... Joint Surg(Am) 199 5, 77 :99 8-1002. 3. Bukart BC, B R, Rorabeck CH, et al: The efficacy of tourniquet release in blood conservation after total knee replacement. Clin Orth 199 4, 299 :147-52. 4. Karnezis ... tourniquet. Lancet 197 7, I :97 0-2. 9. Benoni G, C A, Petersson C, Fredin H: Does Tranexamic Acid reduces blood loss after total knee arthroplasty? Am J Knee Surg 199 5, 8:88 -92 . 10. Petaja J, M ... Transfusion. Anesth Analg 199 8, 86(1) :9- 15. 40. Umlas J, et al: Red cell loss following orthopedic surgery: the case against postoperative blood salvage. Transfusion 199 4, 34(5):402-6. 41. Lee...
Ngày tải lên: 20/06/2014, 04:20
báo cáo hóa học:" Use of Tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement" pdf
... Joint Surg(Am) 199 5, 77 :99 8-1002. 3. Bukart BC, B R, Rorabeck CH, et al: The efficacy of tourniquet release in blood conservation after total knee replacement. Clin Orth 199 4, 299 :147-52. 4. Karnezis ... tourniquet. Lancet 197 7, I :97 0-2. 9. Benoni G, C A, Petersson C, Fredin H: Does Tranexamic Acid reduces blood loss after total knee arthroplasty? Am J Knee Surg 199 5, 8:88 -92 . 10. Petaja J, M ... other indications. Drugs 199 9, 57:1005-32. 18. Bekasssy Z, A B: Treatment with fibrinolytic inhibitor tranexamic acid: risk for thrombosis? Acta Obstet Gynecol Scand 199 0, 69: 353-4. 19. Kataros D, P M,...
Ngày tải lên: 20/06/2014, 07:20
Báo cáo y học: "A rare case of arterial avulsion presenting with occult blood loss following total hip arthroplasty: a case report" docx
Ngày tải lên: 11/08/2014, 14:21