3 vessel reactors for vascular tissue engineering

... neointimal hyperplasia [84, 106] 2.3 Vascular Tissue Engineering (VTE) Vascular tissue engineering (VTE) is an interdisciplinary field involving the principles of engineering and life sciences to ... function and patency of the vascular grafts, the concept of vascular tissue engineering (VTE) that involves the principles of engineering and life sciences in the development of vascular substitutes ... TCP Tissue Culture Plate TEBV Tissue Engineered Blood Vessel TGF-β1 Transforming Growth Factor Beta UV Ultraviolet UV-Vis Ultraviolet-Visible vSMC Vascular Smooth Muscle Cell VTE Vascular Tissue...

Ngày tải lên: 10/09/2015, 09:08

... FUNCTIONAL PERFORMANCE OF EXTRUSION-BASED ADDITIVE MANUFACTURED SCAFFOLDS FOR BONE TISSUE ENGINEERING MUHAMMAD TARIK ARAFAT (B.Sc in Mechanical Engineering, BUET) A THESIS SUBMITTED FOR THE DEGREE ... pore size Small pores induce osteochondral formation before osteogenesis, whilst large pores that are well vascularized induce direct osteogenesis Tissue forms quickly on the outer surfaces of the ... Scaffold-based tissue engineering (TE) aims to aid in the repair and regeneration of bone defects Using this approach, the scaffold acts as a platform which carries cells or therapeutic agents for regenerative...

Ngày tải lên: 10/09/2015, 15:51

... differentiation………………… 21 2.3.4.1 Cartilage tissue engineering using hydrogels……………………… 21 2.3.4.2 Cartilage tissue engineering using polymeric scaffolds…………… 23 2.4 Cartilage formation and regeneration using ... FUNCTIONALITY………………………………………… 98 4.4.1 Cartilage tissue engineering using hESC-derived chondrogenic cells………………………………………………………………… 98 4.4.1.1 Optimal growth factor induction for cartilage tissue engineering 98 vii 4.4.1.2 ... chondrogenic differentiation of ESCs and for cartilage tissue engineering Some of the biomaterials and their associated outcomes in ESC-based cartilage tissue engineering and regenerative medicine...

Ngày tải lên: 11/09/2015, 09:57

... selection for liver tissue engineering 2-11 Scaffold fabrication for liver tissue engineering 2-16 Scaffold surface modification 2-20 Tissue culture for liver tissue engineering ... failure 2-8 2.2 TISSUE ENGINEERING AND APPLICABILITY IN LIVER FAILURE 2-10 2.2.1 Overview of tissue engineering 2-10 2.2.2 Liver tissue engineering 2-11 ... functions Finally, in the context of this liver tissue engineering study, the principles of tissue engineering and the status of current liver tissue engineering research are reviewed in this chapter...

Ngày tải lên: 12/09/2015, 10:22

... BASED MICROCARRIERS FOR BONE TISSUE ENGINEERING APPLICATIONS FENG YONG YAO, JASON B.Eng.(Hons), National University of Singapore A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF ENGINEERING DEPARTMENT ... biomaterial for bone tissue engineering, intended as a single-step cell expansion and in-situ osteogenic differentiation platform to be implemented as a non-invasive, injectable bone graft substitute for ... microcarriers for bone tissue engineering Key Engineering Materials 529530 2013 Conferences (Oral): 1) Feng J, Chong M, Chan J, Zhang ZY, Teoh SH, Thian ES Cell-loaded ceramic based microbeads for direct...

Ngày tải lên: 22/09/2015, 15:18

... has challenged research on tissue engineering strategy in recent years to reconstitute its function when lost by replacing with a functional neotissue (engineering tissue) with similar mechanical ... scaffold for ligament tissue engineering Hence, the objectives of this study are: (i) To design and develop a bi-axial cyclic loading and low shear stress perfusion bioreactor system for ligament tissue ... the conclusions and recommendations for the future development are provided in Chapter CHAPTER 2: LITERATURE SURVEY 2.1 LIGAMENT TISSUE ENGINEERING Tissue engineering represents a new approach...

Ngày tải lên: 04/10/2015, 10:25

... ECM Extracellular matrix MI Myocardial Infarction LV Left Ventricle TE Tissue Engineering CTE Cardiac Tissue Engineering VEGF Vascular Endothelial Growth Factor RGD arginine-glycine-aspartic HFP ... other therapies are experimented for the treatment of the infarcted myocardium, of which the tissue engineering approach is gaining much attention Cardiac tissue engineering promises to bring about ... Advantages of electrospun nanofibers for tissue engineering 17 Chapter 3: Human cardiomyocyte interaction with electrospun fibrinogen/gelatin nanofibers for myocardial regeneration 3.1 Introduction...

Ngày tải lên: 05/10/2015, 19:04

... field of bone tissue engineering for an ideal bone substitute 1.1.3 Strategies in BTE Tissue engineering is the restoration, improvement, maintenance and substitution of damaged tissues and organs ... Instron micro tester for mechanical testing  Ms Irene Kee (Dept of Experimental Surgery, SGH), for her valuable assistance and support during animal surgeries and taking care for them after implantations ... give the reader an overview of the current trends in bone tissue engineering (BTE) Following that, limitations of available treatments for bone defects and various strategies of BTE will be discussed...

Ngày tải lên: 09/10/2015, 11:18

... skeletal tissue, and this treatment strategy was later coined as “bone tissue engineering A key component in tissue engineering for bone regeneration is the scaffold that serves as a 3D template for ... 1.1.1 Bone tissue engineering Loss of human tissues or organs is a devastating problem that can affect individuals of all ages Bone, a complex living tissue that provides internal support for all ... the body allows it to be gradually replaced by cells to form functional tissues [Pollok, 1996] A well-designed scaffold for bone tissue engineering then plays an important role in facilitating...

Ngày tải lên: 09/10/2015, 11:18

... for cardiac tissue replacement, further confirming its huge promise for cardiovascular tissue engineering application This thesis reports on a novel hybrid nanofibrous PCL membrane scaffold for ... dimensional system for tissue engineering application - 20 - Chapter 2: LITERATURE REVIEW - 21 - 2.1 Cardiovascular Tissue Engineering The limitation of existing therapies necessitates the need for alternative ... regenerative medicines mainly including cell therapy and cardiovascular tissue engineering Biomaterial’s application in cardiovascular tissue engineering is then reviewed Then the story will be narrowed...

Ngày tải lên: 26/11/2015, 22:40

... Characterisation Of Vascular Progenitors 4.3 Discussion 4.3.1 Summary of Results In this chapter, I detailed my efforts to identify good cellular sources for vascular tissue engineering While several ... starvation The capacity for 144 Chapter Isolation and Characterisation Of Vascular Progenitors expansion and differentiation support the use of UCPVC for vascular tissue engineering I then proceeded ... best source of EPC for vascular tissue engineering 145 Chapter Isolation and Characterisation Of Vascular Progenitors 4.3.2 Critical Assessment 4.3.2.1 Umbilical Cord Perivascular Cells (UCPVC)...

Ngày tải lên: 14/09/2015, 08:49

... model tissue system to be studied 1.2 Vascular Tissue Engineering Vascular tissue engineering presents an attractive model for LBL tissue engineering for several reasons Firstly, vascular tissue ... surfaces for layered tissue engineering Subsequently, perivascular cells derived from umbilical cord (UCPVC) were found suitable for reconstruction of the perivascular compartment for vascular tissue ... (UCB-EPC) were deemed the most suitable for vascular tissue engineering due to lineage stability The feasibility of microthin PCL films for layered vascular tissue engineering was explored µXPCL film...

Ngày tải lên: 14/09/2015, 08:49

... Chapter Isolation and Characterisation Of Vascular Progenitors Figure 4-3: Primary culture of haemopoietic tissue in EGM Following culture in endothelial cell media, outgrowth ... cells, and failed to express endothelial phenotype 122 Chapter Isolation and Characterisation Of Vascular Progenitors (a) (b) (c) (d) (e) (f) Figure 4-4: CFU assay Adherent colonies appeared after...

Ngày tải lên: 14/09/2015, 08:49

... modified films for possible tissue engineered blood vessel applications Conjugation of a wide variety of biomolecules to blood contacting surfaces has been studied in vascular tissue engineering, ... contribute towards improved biocompatibility of the tissue engineering scaffolds In the specific context of vascular tissue, two other important classes of tissue responses remain First, possible issues ... biocompatibility of µXPCL films for vascular tissue engineering In the context of the application, I have defined blood compatibility and cytocompatibility with vascular cell types to be the most...

Ngày tải lên: 14/09/2015, 08:49

... efforts are required to enhance the beneficial effects of growth factors on tissue engineering 14.3.2 Favorable Environments for Tissue Regeneration There are two modes of tissue engineering for ... of tissue engineering for tissue construction One is in vitro (ex vivo) tissue engineering and the other in vivo (in situ) tissue engineering In the beginning of tissue engineering research, many ... engineering This may be the reason for very limited applications of in vitro tissue engineering mostly to epidermal production Tissue engineering below means the in vivo tissue engineering unless specified...

Ngày tải lên: 25/10/2013, 08:20

... Cells for Tissue Engineering is a new volume in the John Wiley series Culture of Specialized Cells, with focus on procedures for obtaining, manipulating, and using cell sources for tissue engineering ... effort to provide a user-friendly reference for sourcing, characterization, and use of cells for tissue engineering, for researchers with a variety of backgrounds (including basic science, engineering, ... 61 Cell Sources for Cartilage Tissue Engineering Brian Johnstone, Jung Yoo, and Matthew Stewart 83 Lipid-Mediated Gene Transfer for Cartilage Tissue Engineering Henning...

Ngày tải lên: 22/03/2014, 15:20

... surrounded by an astrocytic scar is formed following this tissue loss Where the injury extends to pia mater, collagen will also contribute in the formation of the scar tissue As Approaches to treatment ... and Bunge [31] for review) The core approach of tissue engineering consists of provision of an interactive environment between cells, scaffolds and bioactive molecules to promote tissue repair ... field very slow for many years But, in the last decade, the rapid progress that has been made in the field of tissue engineering as the result of Page 10 of 16 (page number not for citation purposes)...

Ngày tải lên: 19/06/2014, 10:20

... scaffolds, which are used for framework and initial support for the cells to attach, proliferate and differentiate, and form an extracellular matrix, is one area of tissue engineering [2] The goal ... of three-dimensional scaffolds for tissue engineering Chem Eng Res Des 2007, 85:1051-1064 Guarino V, Cause F, Ambrosio L: Bioactive scaffolds for bone and ligament tissue Expert Rev Med Dev 2007, ... phosphate for tissue engineering scaffold Sung-Min Kim1, Soon-Aei Yi1, Seong-Ho Choi2, Kwang-Mahn Kim1, and Yong-Keun Lee*1 Department and Research Institute of Dental Biomaterials and Bioengineering,...

Ngày tải lên: 21/06/2014, 17:20

... Lysaght MJ, Hazlehurst AL: Tissue engineering: The end of the beginning Tissue Engineering 10:12, 2004 Sheih SJ, Vacanti JP: State-of-the-art tissue engineering: From tissue engineering to organ building ... assist device Challenges to Tissue Engineering The greatest success in tissue engineering to date has been in tissues such as skin and cartilage where the requirements for nutrients and oxygen are ... addressed for tissue engineering products to be used widely Ideally, products should be reproducible and available at a wide variety of hospitals, including those without sophisticated facilities for...

Ngày tải lên: 07/07/2014, 01:20