2knowledge engineering in the whole life cycle of manufacturing product

Báo cáo khoa học: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris pdf

Báo cáo khoa học: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris pdf

Ngày tải lên : 06/03/2014, 09:22
... 428 aa; nine aa in total) were located near the interface of the physiological dimer The Cterminal domain may contain structural features involved in protein–protein interactions to form the physiological ... Determination of overall structure In a previous study [10], we determined the F structure containing the truncated region of the C-terminal domain; however, we failed to determine the structure of ... conformations of the regions at 100-105 and 303-309 aa in the N form, and we investigated the following points First, these areas are not involved in any contacts with other molecules in crystals in all the...
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Báo cáo khoa học: Stage specific expression of poly(malic acid)-affiliated genes in the life cycle of Physarum polycephalum Spherulin 3b and polymalatase potx

Báo cáo khoa học: Stage specific expression of poly(malic acid)-affiliated genes in the life cycle of Physarum polycephalum Spherulin 3b and polymalatase potx

Ngày tải lên : 07/03/2014, 12:20
... spherulin 3a and NKA48 contain only a single domain fold The stability of these two proteins is highly dependent on calcium binding [25] The typical domain motives contain a ‘tyrosine corner’ in the ... result of loss of induction at the transcriptional level, of loss of activation of the synthetase protein itself, or of derepression of enzyme(s) catalysing PMLA degradation An interesting interplay ... express a distinct fragmin-like actin-binding Cell type expression of spherulin 3b and polymalatase protein that controls in vivo phosphorylation of actin by the actin-fragmin kinase Eur J Biochem...
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Báo cáo y học: "A role for the histone deacetylase HDAC4 in the life-cycle of HIV-1-based vectors" ppsx

Báo cáo y học: "A role for the histone deacetylase HDAC4 in the life-cycle of HIV-1-based vectors" ppsx

Ngày tải lên : 12/08/2014, 01:21
... might also be involved in intranuclear trafficking of the preintegration complex [20-23] In this study, we have tested the hypothesis that HDAC4 plays a role in the life- cycle of HIV-1-based ... Page of 10 Figure Effect of an integrase inhibitor on the formation of HDAC4 foci in infected cells HeLa cells were infected with the HIV-1-based vector in the presence and absence of the integrase ... observed the appearance of HDAC4 foci in infected cells, with the majority of cells containing foci at hrs post-infection (Figs and 3) Most of the infected cells contained multiple HDAC4 foci As indicated...
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Investigation of the role of the ubiquitin proteasome pathway in dengue virus life cycle 1

Investigation of the role of the ubiquitin proteasome pathway in dengue virus life cycle 1

Ngày tải lên : 09/09/2015, 08:20
... infection in the midgut of the female mosquito after the ingestion of viremic blood Ingestion of an infected blood meal does not guarantee infection in the mosquito Upon ingestion, the virus encounters ... least two barriers: the midgut infection barrier (MIB) preventing infection of the mosquito midgut and the midgut escape barrier (MEB) preventing dissemination of the virus into the hemocoel (Kramer ... via the hemolymph to the other organs, such as the head, salivary glands and ovaries of the mosquito (Black et al, 2002) (Figure 1-10) In these organs, the infection is life- long and the continued...
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Investigation of the role of the ubiquitin proteasome pathway in dengue virus life cycle 3

Investigation of the role of the ubiquitin proteasome pathway in dengue virus life cycle 3

Ngày tải lên : 22/09/2015, 15:18
... exocytosis To elucidate the mechanisms involved, we show in Section 3.3 that perturbation of the UPP leads to ER stress-induced UPR that represses translation of key proteins of the exocyst complex ... NS3 is brown while hematoxylin counterstaining is blue Bortezomib treated mice also showed significantly reduced number of DENV infected cells in the red pulp of the spleen at 24 and 48 hpi compared ... alleviated inflammatory responses in DENV infected C57BL/6 mice (A-B) DENV2-infected vehicle control displayed an increased systemic level of MCPT1, indicative of mast cell activation, in mouse...
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Investigation of the role of the ubiquitin proteasome pathway in dengue virus life cycle 4

Investigation of the role of the ubiquitin proteasome pathway in dengue virus life cycle 4

Ngày tải lên : 22/09/2015, 15:18
... proteins by up-regulating host factors that increase the capacity of the ER to handle the synthesis of nascent proteins   115     (Ron & Walter, 2007) The life cycle of DENV and other members of ... to line a plastic incubation container 10 Place the slides in the incubation container Gently place the lid on the container and incubate at 37 °C for 30 11 Remove and rinse slides in staining ... and infectious virus titers in human sera Viremia (infectious virus) in humans is influenced by the strain of virus, the day of infection the serum was collected from the patient, and the individual’s...
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Investigation of the role of the ubiquitin proteasome pathway in dengue virus life cycle 2

Investigation of the role of the ubiquitin proteasome pathway in dengue virus life cycle 2

Ngày tải lên : 22/09/2015, 15:18
... the establishment of a successful infection in these organs, the infection is life- long and the continued production of DENV, especially in the salivary glands, enables infection of new susceptible ... in humans is influenced by the strain of virus, the day of infection the serum was collected from the patient, and the individual’s previous dengue experience, which influences the innate and adaptive ... following an infectious blood meal We hypothesized that differential regulation of the proteasome or other genes in the UPP could be involved in the observed reduction in infectious DENV-2 titers in...
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The Economics of Small Business Finance: The Roles of Private Equity and Debt Markets in the Financial Growth Cycle potx

The Economics of Small Business Finance: The Roles of Private Equity and Debt Markets in the Financial Growth Cycle potx

Ngày tải lên : 15/03/2014, 21:20
... terms on some of the individual loans issued by a sample of banks, including the largest banks in the nation Beginning in 1997, the STBL includes the banks’ risk ratings on their individual loans, ... by the one or more of the inside owners, giving the financial institution recourse against their personal wealth in the event the loan is not repaid In many cases, the personal assets of the insiders ... information of the intermediary with the business, the business owner, or other involved then uses this information contract terms at origination garnered about the initial quality of the small business...
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ANNALS OF THE NEW YORK ACADEMY OF SCIENCES - Full cost accounting for the life cycle of coal potx

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES - Full cost accounting for the life cycle of coal potx

Ngày tải lên : 23/03/2014, 00:20
... life cycle of coal Epstein et al Table The life cycle impact of the U.S coal industry Economic Underground coal mining MTR mining Coal mining Human health Federal and state subsidies of coal industry ... in heavy coal mining areas of Appalachia, less so in light coal mining areas, lesser still in noncoal mining areas in Appalachia, and lowest in noncoal mining areas outside of Appalachia Another ... occur In January 2006, 17 miners died in Appalachian coal mines, including 12 at the Sago mine in West Virginia, and 29 miners died at the Upper Big Branch Mine in West VA on April 5, 2010 Since...
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Báo cáo khoa học: Analysis of the contribution of changes in mRNA stability to the changes in steady-state levels of cyclin mRNA in the mammalian cell cycle doc

Báo cáo khoa học: Analysis of the contribution of changes in mRNA stability to the changes in steady-state levels of cyclin mRNA in the mammalian cell cycle doc

Ngày tải lên : 30/03/2014, 20:20
... well with the estimated doubling time of EL4 cells in logarithmic growth No major variation in the mRNA half -life of cyclin mRNAs in the cell cycle In order to test whether changes in mRNA steadystate ... the cell cycle [11–15] Certain transacting proteins such as HuR were proposed as regulators of changes in mRNA stability during the cell cycle [15] In this context it is of interest that during ... the changes in mRNA half -life may explain almost fully the accumulation of the short A2 and B1 transcripts as well as partially the 3.0-kb A2 transcript In contrast, the greater increase of the...
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handbook of biochemical kinetics a guide to dynamic processes in the molecular life sciences

handbook of biochemical kinetics a guide to dynamic processes in the molecular life sciences

Ngày tải lên : 01/04/2014, 10:21
... contain high concentrations of actin filaments as well as other actin-binding proteins, including Ͱ-actinin, vinculin, zyxin, paxillin, and talin Microinjection of the FEFPPPPPTDE peptide into uninfected ... assembly of actin-based motor complexes from a battery of regulatory proteins These include capping proteins, severing proteins, sequestering proteins, bundling and cross-linking proteins, actin-related ... monomers The affinity of a capping protein can be readily determined as the concentration of capping protein needed to inhibit the initial rate of dilutioninduced disassembly of polymer containing...
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Báo cáo hóa học: " Research Article A Hilbert-Type Integral Inequality in the Whole Plane with the Homogeneous Kernel of Degree −2 Dongmei Xin and Bicheng Yang" pdf

Báo cáo hóa học: " Research Article A Hilbert-Type Integral Inequality in the Whole Plane with the Homogeneous Kernel of Degree −2 Dongmei Xin and Bicheng Yang" pdf

Ngày tải lên : 21/06/2014, 05:20
... have the reverse of 2.10 and 3.3 It is ¨ easy to obtain the reverse of 3.2 In view of the reverses of 3.2 and 3.3 , we obtain the reverse of 3.1 On the other hand, suppose that the reverse of ... contradiction that the constant factor in the reverse of 3.1 is not the best possible Thus the theorem is proved By the same way of Theorem 3.3, we still have the following theorem Theorem 3.4 By the assumptions ... Setting the same g y as Theorem 3.1, by the reverse of 2.10 , we have J > If J ∞, then the reverse of 3.2 is obvious value; if J < ∞, then by the reverse of 3.1 , we obtain the reverses of 3.5...
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Life in the city is full of activityLife in the city is full of activity. docx

Life in the city is full of activityLife in the city is full of activity. docx

Ngày tải lên : 21/07/2014, 20:20
... full of noise Hundreds of sight-seers tourists and others visit many place of interest in the city while businessmen from various parts of the world arrive to transact business The towards evening, ... For the greed of a few, many are killed, and some live in constant fear To bring criminals to justice, the officers of the law are always on the move Workers and others who seek advancement in their ... the city before finds it hard to move about at this time Soon, however, there is almost no activity in several parts of the city These parts are usually the business centers With the coming of...
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Báo cáo y học: "A ball valve blood clot in the airways – life-saving whole tube suction" pps

Báo cáo y học: "A ball valve blood clot in the airways – life-saving whole tube suction" pps

Ngày tải lên : 12/08/2014, 20:20
... withdrawal of the tube, which resulted in extraction of the clot from the tube fibreoptic bronchoscopy revealed that the clot had advanced into the left main bronchus, and was now obstructing the left ... lung during both inspiration and expiration Intensive chest physiotherapy with the patient lying on the right side, combined with both suctioning and the use of a small forceps through the fibreoptic ... bronchus until the distal end of the oropharyngeal tube was against the blood clot Then the bronchoscope was removed, and suction was applied with the distal end of the oropharyngeal tube in direct...
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Báo cáo y học: "Inhibition of early steps in the lentiviral replication cycle by cathelicidin host defense peptides" pptx

Báo cáo y học: "Inhibition of early steps in the lentiviral replication cycle by cathelicidin host defense peptides" pptx

Ngày tải lên : 13/08/2014, 13:20
... [9] Cathelicidins have since been identified in many other species including hCAP18/LL37 in humans [10], protegrins in swine [11-13], CRAMP in mice [14,15] and SMAP29 in sheep [16] Many of these ... value of the triplicates was expressed as percent of the mean of triplicates of control cultures infected with the same vector in the absence of HDPs and the mean and the standard deviation of the ... window for therapeutic intervention of bacterial infection However, for the treatment of HIV-1, the therapeutic window of LL37 and PG-1 is rather narrow It should also be noted that the HDPinduced...
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Defect engineering in the formation of ultra shallow junctions for advanced nano metal oxide semiconductor technology

Defect engineering in the formation of ultra shallow junctions for advanced nano metal oxide semiconductor technology

Ngày tải lên : 11/09/2015, 09:58
... surface during the annealing It reduces the concentration of excess silicon interstitials available in the junctions, thus minimizing the interactions between the B 10 Summary  and point defects ... Chapter 2  Another scaling issue lies in the gate electrode of the transistor The use of polysilicon gate is the key advance in today MOS technology, since it allows the selfalignment of source/drain junctions ... characteristics In addition, understanding of the influence of co-implanted N atoms on the interactions 31 Chapter 1  between dopants and defects is investigated Finally, the competency of the junctions...
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A double blind randomized placebo controlled clinical trial on the supplementation of probiotics in the first six months of life in asian infants at risk of allergic diseases   effe

A double blind randomized placebo controlled clinical trial on the supplementation of probiotics in the first six months of life in asian infants at risk of allergic diseases effe

Ngày tải lên : 11/09/2015, 21:39
... maintaining the integrity of the intestinal barrier In addition, Yan et al reported the increase survival of intestinal cells in the presence of L rhamnosus GG through the prevention of cytokine-induced ... 1.1.4 The microflora hypothesis of allergic disease The role of the indigenous intestinal microbiota has further been proposed to potentially outweigh that of infections in immune maturation The ... The differential regulation suggested that the composition of the gut microflora can modify immune response Cytokines produced following the interaction of probiotics with the intestinal epithelium...
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The Portlet Life Cycle

The Portlet Life Cycle

Ngày tải lên : 05/10/2013, 04:20
... collection of the portlet Creation of the Portlet The creation of the portlet is probably the most complex “phase” in the life cycle since it involves three quite distinct steps However, two of them—loading ... rendering fragments of pages, so there’s an obvious correlation The life cycle of a portlet therefore breaks down into the following stages: Creation of the portlet Processing of a number of user ... Page 71 The Portlet Life Cycle Summary In this chapter, we have discussed the life cycle of a portlet The portlet container calls the init() method on the portlet to initialize the portlet, the portlet...
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