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Cấu trúc
Osteoporosis research: Current Concepts and Research
NéI dung
Normal vs Osteoporosis
Osteoporosis
Thay ®æi quan ®IÓm
G·y x¬ng
Tû lÖ g·y x¬ng theo tuæi
PowerPoint Presentation
Ng· vµ nguy c¬ ng·y x¬ng
Postural Sway Test
Risk Factors
Risk Factors for Low Bone Mass
Slide 13
Bone Mineral Density
Femoral Neck
Vertebrae
Areal Density and Volumetric Density
BMD and Age
BMD T-score
BMD T-score
BMD Z-score
Slide 22
Diagnosis of Osteoporosis
BMD and Fracture Risk
Predictive Value of BMD
BMD-independent risk factors for hip fracture
Risk of hip fracture by BMD and number of risk factors
Bone Turnover Markers
Purposes of Bone Turnover Markers
Slide 30
Slide 31
Basic Prevention
Calcium Supplementation
Fall Prevention
Treatments
Efficacy of Treatments
Slide 37
New Findings (up to 2004)
Slide 39
Hot Topics of Research
Topic 1. Non-BMD factors for predicting fx
Rate of hip fracture by BMD and ICTP
Topic 2. How to identify high-risk individuals
An example of scoring
Evaluation of the scoring system
Topic 3. Genes and fracture risk
Slide 47
An example of genetic association study
Research topics for Vietnam
Slide 50
Slide 51
Slide 52
Slide 53
Summary
May I advise …
Slide 56
Slide 57
The Future: A risk score calculator
Nội dung
Osteoporosis research: Current Concepts and Research Dr Tuan V Nguyen Associate Professor Bone and Mineral Research Program Garvan Institute of Medical Research Sydney, Australia Garvan Institute of Medical Research NéI dung ã định nghĩa khái niệm ã Các yếu tố nguy ã Chẩn đoán đo mật độ xơng ã điều trị ã Nhng điểm mới? Garvan Institute of Medical Research Normal vs Osteoporosis Garvan Institute of Medical Research Osteoporosis Osteoporosis: LoÃng xơng (LX) bệnh chuyển hoá xơng, đợc đặc trng khối lợng xơng thấp tới mức làm xơng giòn dẫn tới nguy c¬ g·y x¬ng (Consensus Development Conference, 1991) Garvan Institute of Medical Research Thay đổi quan đIểm LoÃng xơng: Yếu tố nguy c¬ Ng·y x¬ng: HËu qua Garvan Institute of Medical Research G·y x¬ng Garvan Institute of Medical Research Tû lƯ g·y x¬ng theo ti Ty le mac moi/100,000 dan 500 Nu 400 Nam 300 200 100 0-4 5-14 1524 2534 3544 4554 5564 6574 7584 85+ Garvan Institute of Medical Research ã định nghĩa khía niệm ã Các yếu tố nguy ã Chẩn đoán đo mật độ xơng ã điều trị ã Nhng điểm mới? Garvan Institute of Medical Research Ngà nguy ngÃy xơng Yếu tứ đầu T không ổn định Ngà NgÃy xơng đùi ã Interaction between BMD and fall-related factors in the prediction of hip fracture Garvan Institute of Medical Research Postural Sway Test Garvan Institute of Medical Research An example of scoring Variable Score Age