Chemical composition, antioxidant activity and antibacterial mechanism of action from Marsilea minuta leaf hexane: Methanol extract

In the present study, hexane: Methanol (50:50) leaf extract of Marisela minuta has been evaluated for its chemical composition, antioxidant effect and the antimicrobial mechanism of action against food borne pathogenic bacteria.

(2018) 12:105 Arokiyaraj et al Chemistry Central Journal https://doi.org/10.1186/s13065-018-0476-4 Chemistry Central Journal Open Access RESEARCH ARTICLE Chemical composition, antioxidant activity and antibacterial mechanism of action from Marsilea minuta leaf hexane: methanol extract Selvaraj Arokiyaraj1†, Rajaraman Bharanidharan2,3†, Paul Agastian4 and Hakdong Shin1* Abstract  Background:  In the present study, hexane: methanol (50:50) leaf extract of Marisela minuta has been evaluated for its chemical composition, antioxidant effect and the antimicrobial mechanism of action against food borne pathogenic bacteria Results:  The phytochemical evaluation of extract by GC/MS revealed the major abundance of benzoic acid-4-ethoxyethyl ester (43.39%) and farnesol acetate (18.42%) The extract exhibited potential antioxidant and free radical scavenging properties with promising antibacterial activities against the test pathogens with Pseudomonas aeruginosa being the most susceptible with maximum inhibition zone (17 mm) and I­C50 value of 125 µg, respectively The significant (p