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MINISTRY OF EDUCATION AND TRAINING MINISTRY OF HEALTH HANOI MEDICAL UNIVERSITY NGUYEN THI MAI LAN INCIDENCE RATE OF FEMALE BREAST CANCER IN HANOI PERIOD 2014 – 2016 Specialty: Oncology Code: 62720149 SUMMARY OF PhD THESIS IN MEDICINET HANOI – 2020 THE STUDY IS COMPLETED AT HA NOI MEDICAL UNIVERSITY Mentor: Professor Bui Dieu Opponent 1: Opponent 2: Opponent 3: The thesis will be presented committee of Ha Noi medical university at o’clock day month year 2020 The thesis could be found in: National Library Library of Hanoi Medical University INTRODUCTION Breast cancer (breast cancer) is not only the most common cancer in women but also one of the main causes of death for women in many countries According to GLOBOCAN 2018, there were 2,089,000 newly diagnosed breast cancer cases worldwide, accounting for 11.6% of all cancers and the number of deaths from breast cancer was 881,000 Therefore, the prevention of cancer in general and breast cancer in particular is always considered as one of the top health issues In many developed countries, the National Cancer Prevention Program (PCUT) is geared to: disease prevention; screening and early detection; improve the quality of diagnosis and treatment of diseases and improve the quality of life for people with cancer However, the development of an effective PCUT program depends heavily on cancer epidemiological studies Epidemiological data on cancer such as disease burden, age distribution, socio-economic, geographic area, trends of disease are decisive in determining priority priorities for the PCUT program in each country In particular, the incidence and mortality are two important indicators to help assess the situation of cancer The incidence of cancer is only obtained from population-based records The death rates due to cancer in countries are based on mortality statistics by disease causes This type of statistics is available in most developed countries and some developing countries In some other developing countries, death certificates are often not certified by a physician about the cause of death Therefore, in these areas, the death rate from cancer or the given figures are not much lower than the actual ones In Vietnam, breast cancer is the leading cancer among women According to cancer records in Hanoi, Ho Chi Minh City and some provinces, the standardized breast cancer rate by age in 2010 was 23 / 100,000 people, ranking first among all female cancers This is one of the slow progressing cancers, with a good prognosis if detected early and treated promptly Prevention of breast cancer and screening for early detection of breast cancer are increasingly being paid attention, especially in some big cities such as Hanoi, Ho Chi Minh, Hai Phong, Thai Nguyen, Hue and Can Tho Studies of breast cancer in Vietnam often focus on diagnosis, treatment and improvement of quality of life for patients In contrast, breast cancer epidemiology studies have received little attention, while results from these types of studies have important implications for cancer prevention In order to provide more epidemiological data to health authorities in developing effective breast cancer prevention strategies, we implement the project “Incidence rate of female breast cancer in Hanoi from 2014 to 2016” with two aims: Objectives: Determine the incidence of breast cancer in women in Hanoi from 2014 to 2016 and trend of breast cancer Evaluation of the overall duration of new breast cancer in Hanoi women from 2014-2016 and related factors These new findings of the thesis: This is the first study in Vietnam report the epidemiology of breast cancer in Hanoi from 2014 to 2016, providing important information on epidemiological characteristics and overall survival Results from the study showed that: - The number of new breast cancer cases in Hanoi women in 2014-2016 is 3.502 - The highest age group is 50-59 years old, accounting for 30.1% - The crude rate is 31.0/100,000 women The age-standardized rate is 29.4/100,000 women - The age-standardized rate in urban areas (38.9/100,000 females) is higher than in urban areas (21.7/100,000 females) - The crude rate in urban areas (41.1/100,000 females) is higher than in suburban areas (23.4/100,000 females) Survival time - Median overall survival time was 52.7 ± 0,3 (months) The overall survival rate of years, years, and the estimated for years is 92.3%; 90.9% and 86.2% - In the young breast cancer group (