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PCI vs CABG Left Main Disease and Multi-Vessel Disease The Game Is Not Over ! Seung-Jung Park, MD, PhD Professor of Medicine, University of Ulsan College of Medicine Asan Medical Center, Seoul, Korea Background of “Surgery is Better” First Randomized Trial CABG vs Medical Treatment From 1975 to 1979, 780 patients with Stable Ischemic Heart Disease, Surgical (n=390) vs Medical (n=390) 70%, or vessel disease, Only long acting nitrate and beta blocker available, [...]... (0.60,1.48) 2.06 (1 .36 ,3. 13) 0.56 (0 .32 ,0.98) 2. 73 (1.86,4. 03) 1.15 (0.80,1. 63) 4 yrs 0.84 (0. 53, 1 .33 ) 1.12 (0.75,1.68) 0.57 (0 .38 ,0.86) 2. 73 (1.86,4. 03) 0. 83 (0.62,1.11) 5 yrs 0.79 (0.67,1.08) 1 .38 (0.71,2.70) 0.27 (0. 13, 0.55) 3. 77 (2. 43, 5.87) 0.64 (0.51,0.80) 30 days 0.47 (0.20,1.10) PCI 0.71 (0.55,0.92) Better 1.41 (0.56 ,3. 51) 0.24 (0.10,0.62) 0.74 (0 .30 ,1.85) 0.55 (0.18,1. 63) 1 .32 (0.75,2 .31 ) 0.22 (0.10,0.49)... (n=14,2 03) , 20 13 Death, MI or Stoke at 5 Year Time Point No of Studies Sample Size Statistics Odds ratio Lower limit Upper limit p-Value 1 Year 9 4515 0. 938 0.659 1 .33 7 0.72 2 Year 8 49 53 1.011 0. 739 1 .38 3 0.95 3 Year 5 31 04 1.149 0.608 1. 633 0.44 4 Year 4 532 9 0.829 0.619 1.110 0.20 5 Year 5 33 60 0.641 0.512 0.8 03