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[...]... interval (age) 55 45 35 25 n ϭ 13 15 21 21 21 32 16 17 24 19 18 12 21 22 28 27 35 39 46 44 16 11 19 78 19 80 19 82 19 84 19 86 19 88 19 90 19 92 19 94 19 96 19 98 Year of surgery Fig 3 Distribution of males in the years from 19 78 to 19 99 Age in Patients with Otosclerosis 21 160 14 0 Female Male Number of cases 12 0 10 0 80 60 40 20 0 19 78 19 82 19 86 19 90 19 94 19 98 19 80 19 84 19 88 19 92 19 96 Year of surgery Fig 4 Increase in... 60 51 61 60 43 34 48 43 43 46 58 44 67 83 94 10 2 11 4 13 6 41 38 Total 1, 3 51 Mean age Ϯ SD years 39.60 Ϯ 10 .83 40 .12 Ϯ 9.93 37.88 Ϯ 13 .54 42.22 Ϯ 11 .47 42 .16 Ϯ 11 .28 40 .17 Ϯ 13 .69 44 .12 Ϯ 12 .40 43.82 Ϯ 12 .76 45.67 Ϯ 11 .32 41. 16 Ϯ 12 .06 42.84 Ϯ 11 .93 38.93 Ϯ 13 . 31 40.74 Ϯ 13 .13 43.95 Ϯ 13 .04 43.03 Ϯ 12 .63 45.70 Ϯ 11 .27 45.36 Ϯ 12 .26 47.50 Ϯ 13 .32 45.69 Ϯ 11 .97 46.05 Ϯ 13 .27 44.29 Ϯ 12 .68 45.05 Ϯ 10 .88... audiogram and speech data for Freiburger monosyllabic words, tympanogram, stapedial reflex and radiography of the mastoid The footplate fragments were Niedermeyer/Häusler/Schwub/Neuner/Busch/Arnold 18 Table 1 Average age of patients in the recruitment period from 19 78 to 19 99 Year of surgery Patients n 19 78 19 79 19 80 19 81 1982 19 83 19 84 19 85 19 86 19 87 19 88 19 89 19 90 19 91 1992 19 93 19 94 19 95 19 96 19 97 19 98 19 99... today in modified form References 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 Valsalva AM: The Human Ear (Latin) Bononiae: C Pisarri, 17 04 Schrader M: Geschichte der Otosklerose ORL Nova 19 98;8 :1 6 Menière P: De l’exploration de l’appareil auditif, ou recherches sur les moyens prospres à conduir au diagnostic des maladies de l’oreille Gaz Med Paris 18 42 ;10 :11 4 11 7 Kessel J: Über die Durchschneidung... Otolaryngol Suppl 19 74;324 :1 20 Pearson RD, Kurland LT, Cody DTR: Incidence of diagnosed clinical otosclerosis Arch Otolaryngol 19 74;99:288–2 91 Gapany-Gapanavicius B: Otosclerosis: Genetics and Surgical Rehabilitation New York, Halsted Press, 19 75 Prevalence of Histologic Otosclerosis 15 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Ben Arab S, Bonaiti-Pellié C, Belkahia A: A genetic study of otosclerosis. .. in Patients with Otosclerosis 19 95% confidence interval (age) 55 50 45 40 35 30 n ϭ 42 43 60 51 61 60 43 34 48 43 43 46 58 44 67 83 94 10 2 11 4 13 6 19 78 19 80 19 82 19 84 19 86 19 88 19 90 19 92 19 94 19 96 Year of surgery Fig 1 Statistical analysis of the patients’ average age over the period of recruitment univariate analysis of the distribution of gender The difference of age between women and men (p ϭ 0.398)... bones, n Otoslcerotic individuals, n Prevalence, % Weber [17 ] Engström [16 ] Guild [3] Jørgensen and Kristensen [18 ] Schuknecht and Kirchner [15 ] Hueb et al [19 ] ? 61 ? 237 200 34 518 15 5 ? 8 ? 27 ? 4 43 18 10 11 .8 8.3 11 .4 634 ? ? ? 4.4 ? 643 14 4 82 12 .75 8.3 ϫ 12 /10 0 ϭ 0.99%, respectively These extrapolations for calculating the prevalence of clinical otosclerosis do not correlate well with the clinical... Laryngol 19 58;67:932–9 51 Schuknecht HF: Stapedotomy and graft-prosthesis operation Acta Otolaryng (Stockh) 19 60; 51: 2 41 243 Guilford F: Panel on techniques and results of stapes surgery Arch Otolaryngol 19 63;78:546–573 Schuknecht HF, Applebraunn EL: Surgery for hearing loss N Engl J Med 19 69;280 :11 54 11 60 Plester D: Forstschritte in der Mikrochirurgie des Ohres in den letzten 10 Jahren HNO 19 70 ;18 : 33–40... Ann Genet 19 93;36 :11 1 11 6 Schuknecht HF, Kirchner JC: Cochlear otosclerosis: fact or fantasy? Laryngoscope 19 74;84: 766–782 Engström H: On the frequency of otosclerosis Acta Otolaryngol 19 39;27:608– 614 Weber M: Otosklerose und Umbau der Labyrinthkapsel Leipzig, Poeschel and Trepte, 19 35 Jørgensen MB, Kristensen HK: Activity of otosclerosis assessed histologically J Laryngol Otol 19 67; 81: 911 – 914 Hueb... Ohrenheilkund 19 58 ;17 3:404–406 Zöllner F: Technik der Formung einer Columella aus Knochen Z Laryng Rhinol 19 60;39:436 Pfaltz CR, Piffko P: Substitution of the stapedial arch by free cartilage grafts Arch Otolarngol 19 68;87:47– 51 Prof Rudolf Häusler Department of ENT, Head and Neck and Cranio-Maxillo-Facial Surgery University of Bern, Inselspital CH–3 010 Bern, Switzerland Tel ϩ 41 31 632 29 21, Fax ϩ 41 31 632 . Reinhardt Druck, Basel ISSN: 0065–30 71 ISBN -1 0 : 3–8055– 811 3–0 ISBN -1 3 :978–3–8055– 811 3–4 Library of Congress Cataloging-in-Publication Data Otosclerosis and stapes surgery / volume editors, Wolfgang. by Boucheron [9] and Pottier [10 ] and in Italy by Feraci [11 ]. In the USA, Blake [12 ] and Jack [13 15 ] at the Eye and Ear Infirmary in Boston and also Sexton [16 ] and Alderton [17 ] in New York. Otolarngol 19 68;87:47– 51. Prof. Rudolf Häusler Department of ENT, Head and Neck and Cranio-Maxillo-Facial Surgery University of Bern, Inselspital CH–3 010 Bern, Switzerland Tel. ϩ 41 31 632 29 21, Fax ϩ41