Malnutrition and Nutritional Assessment Part 1 Harrison's Internal Medicine > Chapter 72.. Malnutrition and Nutritional Assessment Malnutrition and Nutritional Assessment: Introductio
Trang 1Chapter 072 Malnutrition and Nutritional Assessment
(Part 1)
Harrison's Internal Medicine > Chapter 72 Malnutrition and Nutritional
Assessment
Malnutrition and Nutritional Assessment: Introduction
Malnutrition can arise from primary or secondary causes, with the former resulting from inadequate or poor-quality food intake and the latter from diseases that alter food intake or nutrient requirements, metabolism, or absorption Primary malnutrition occurs mainly in developing countries and under conditions of war or famine Secondary malnutrition, the main form encountered in industrialized countries, was largely unrecognized until the early 1970s, when it became appreciated that persons with adequate food supplies can become malnourished as
Trang 2underscores the importance of preventing, detecting, and treating malnutrition
Protein-Energy Malnutrition
The two major types of PEM are marasmus and kwashiorkor These
conditions are compared in Table 72-1 Marasmus and kwashiorkor can occur
singly or in combination, as marasmic kwashiorkor Kwashiorkor can occur
rapidly, whereas marasmus is the end result of a gradual wasting process that passes through stages of underweight, then mild, moderate, and severe cachexia
Table 72-1 Comparison of Marasmus and Kwashiorkor
Clinical
setting
Energy intake Protein intake during
stress state
Trang 3Marasmus Kwashiorkora
Time course
to develop
Months or years Weeks
Clinical
features
Starved appearance Well-nourished
appearance
Weight <80%
standard for height
Easy hair pluckabilityb
Triceps skinfold <3
mm
Edema
Mid-arm muscle
circumference <15 cm
Laboratory Creatinine-height Serum albumin <2.8
Trang 4Total iron-binding
capacity <200 µg/dL Lymphocytes <1500/µL
Clinical
course
Reasonably preserved responsiveness to short-term stress
Infections
Poor wound healing,
decubitus ulcers, skin breakdown
Trang 5Marasmus Kwashiorkora
Mortality Low unless related to
underlying disease
High
Diagnostic
criteria
Triceps skinfold <3
mm
Serum albumin <2.8 g/dL
Mid-arm muscle
circumference <15 cm
At least one of the following:
Poor wound healing,
decubitus ulcers, or skin breakdown
Easy hair pluckabilityb
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Edema
a
The findings used to diagnose kwashiorkor must be unexplained by other causes
b
Tested by firmly pulling a lock of hair from the top (not the sides or back),
grasping with the thumb and forefinger An average of three or more hairs removed easily and painlessly is considered abnormal hair pluckability