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MINISTRY OF EDUCATION MINISTRY OF HEALTH & TRAINING HANOI MEDICAL UNIVERSITY ĐINH QUỐC KHÁNH CURRENT SITUATION OF TYPE DIABETES AMONG EMPLOYEES WHO FREQUENTLY HAVE TO WORK SHIFTS, OVERTIME AND SOME RISK FACTORS Major: Public Health Code: 62720301 SUMMARY OF PUBLIC HEALTH DOCTORAL DISSERTATION HÀ NỘI - 2021 THIS WORK IS COMPLETED AT HANOI MEDICAL UNIVERSITY Instructor: Assoc.Prof Dr Khuong Van Duy Dr Nguyen Ngọc Anh Reviewer 1: Reviewer 2: Reviewer 3: The dissertation will be defended in front of the School-level Doctoral Examination Council at Hanoi Medical University At … , (day) … (month) … 2022 The dissertation can be found at: - National Library - Central medical Library - Library of Hanoi Medical University DANH MỤC CÁC CHỮ VIẾT TẮT Chữ viết tắt Tiếng Việt Tiếng Anh ADA Hội đái tháo đường Hoa Kỳ American Diabetes Association BMI Chỉ số khối lượng thể Body Mass Index DTH Dịch tễ học ĐH Đường huyết ĐHBK Đường huyết ĐHLĐ Đường huyết lúc đói ĐTĐ Đái tháo đường ĐTNC Đối tượng nghiên cứu FPG Glucose huyết tương lúc đói Fasting plasma glucose Hormon tăng trưởng) Growth hormon Lippoprotein có tỷ trọng High density lipoprotein cao cholesterol Liên đoàn Đái tháo đường International Diabetes giới Federation IFG Rối loạn glucose lúc đói Impaired Fasting Glucose IGT Rối loạn dung nạp glucose Impaired Glucose Tolerance LDL Chỉ số mỡ máu Low-density lipoprotein NC Nghiên cứu NLĐ Người lao động GH HDLC IDF NPDNGĐU Nghiệm pháp dung nạp glucose đường uống OGTT Oral glucose tolerance test Pre-diabetes Tiền đái tháo đường RLCH Rối loạn chuyển hóa RLĐH Rối loạn đường huyết RLĐHLĐ Rối loạn đường huyết lúc đói RLDNG THA UNICEF WDF Rối loạn rối loạn dung nạp glucose Tăng huyết áp Quỹ nhi đồng Liên hiệp quốc United Nations Children’s Fund Quỹ Đái tháo đường giới WHO Tổ chức Y tế Thế giới XN Xét nghiệm World Health Organization INTRODUCTION Currently, type diabetes tends to increase rapidly in developing countries where there are rapid economic, lifestyle and urbanization changes Diabetes is a highly social disease in many countries, the incidence of type diabetes varies in continents and regions In the world there are a number of studies on the incidence of type Diabetes in workers that shows a relationship between occupational risk factors such as shift work, overtime In Vietnam, there have been many epidemiological studies on the prevalence and risk factors of type diabetes in the community, but few studies related to the prevalence of diabetes in workers such as shift work, overtime So is working overtime or shift work a risk of diabetes in employees? This is an urgent issue that needs to be studied and identified To find out this issue, we conducted research at facilities: Duc Giang Garment Joint Stock Company is an organized facility for employees to work overtime; Proconco forage factory organized for shift workers and overtime; Son Nam Textile and Garment Company organizes for employees to work shifts with the research topic: "Current situation of type diabetes among workers who regularly have to work shifts, overtime and some risk factors", with specific objectives: Determine the current situation of glucose tolerance disorder and diabetes prevalence rate per employee in shift and/or overtime at Proconco Animal Feed Factory, DucGiang Garment Joint Stock Company, Son Nam Textile and Garment Joint Stock Company, 2014-2017 Analysis of the relationship between the rate of impaired glucose intolerance, diabetes with some factors in shift workers, overtime at three companies and factories New contributions of the thesis The dissertation has determined the rate of glucose tolerance disorder and the prevalence of diabetes in workers working in shifts and overtime The thesis also specifies the health characteristics, diseases, and occupational diseases as well as the effects of work-shift related to health and the occurrence of diabetes on employees The thesis layout The thesis consists of 136 pages (Introduction: 03 pages; Chapter 1: Document overview 42 pages; Chapter 2: Subject and research method 14 pages; Chapter 3: Research results 37 pages; Chapter 4: Discussion 36 pages; Conclusions and recommendations 04 pages) There are 24 tables, 03 charts, 02 maps and 02 diagram References: 122 (Vietnamese: 45, English: 77) The appendix includes sample research papers, some data tables and identification of study participants Chapter OVERVIEW 1.1 Diabetes mellitus 1.1.1 Definition Diabetes is a group of metabolic conditions characterized by hyperglycemia due to impaired insulin secretion, impaired insulin activity, or both Chronic hyperglycemia in Diabetes will damage, dysfunction or impair many organs, especially the eyes, kidneys, nerves, heart and blood vessels 1.1.2 Diagnosis of diabetes according to WHO and ADA 1.1.2.1 Determined Diagnosis of diabetes Criteria for diagnosis of Diabetes - WHO; IDF - 2012, based on one of the criteria: - Fasting plasma glucose level ≥7,0mmol / L (≥126mg / dl) Or: - Plasma glucose level ≥ 11.1mmol / L (200mg / dl) hours after the oral glucose tolerance test Or: - HbA1c ≥ 6.5% (48mmol / L according to the International Federation of Clinical Biochemistry-IFCC) 1.1.2.2 Diagnosis of prediabetes - Impaired Glucose tolerance (IGT): if plasma glucose at hours after oral glucose tolerance test from 7.8mmol / L (140mg / dL) to 11.0mmol / L (200mg /dL) - Impaired Fasting blood glucose (IFG): if fasting plasma glucose (8 hours after meals) is from 5.6mmol / L (100mg / dL) to 6.9mmol / L (125mg / dL), and plasma glucose At hours of the test, blood glucose tolerance is below 7.8mmol /L (
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