Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications ppt

[...]... ligands where trigonal bipyramidal coordination is adopted Nitrogen- and oxygen-containing mul- 46136_book.fm Page 4 Friday, February 16, 2007 3:24 PM 4 Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications tidentate ligands such as aminopolycarboxylates are common ligands that strongly complex V(III) [11] Complexes of such ligands are generally monomeric, but with some ligands... behavior 2.1.4 1 H AND 13C NMR SPECTROSCOPY Most of the normally encountered applications of proton and carbon NMR spectroscopy have been applied in studies of vanadate complexes, complexation reactions, equilibria, and kinetics Carbon-13 studies of the influence of complexation 46136_book.fm Page 14 Friday, February 16, 2007 3:24 PM Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications. .. chemical shift ranges are derived from the work of Howarth and coworkers [14, 46, 47] and Crans and coworkers [11, 12, 48] 46136_book.fm Page 16 Friday, February 16, 2007 3:24 PM 16 Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications it will be expected to disperse more freely into the interior of the bilayer Micelles and reversed micelles represent a special case of anisotropic... Seeking a clue to understand the role of vanadium(III) in ascidians Coord Chem Rev 237:147–161 46136_book.fm Page 6 Friday, February 16, 2007 3:24 PM 6 Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications 12 Money, J.K., K Folting, J.C Huffman, and G Christou 1987 A binuclear vanadium(III) complex containing the linear [VOV]4+ unit: Preparation, structure, and properties of tetrakis(dimethylaminoethanethiolato)oxodivanadium... chemistry of the V(V) oxoanion, vanadate, but also describes applications in biochemistry, pharmacology, and technology The chemistry described includes the self-condensation reactions of vanadate and its reactions with a number of mono- and oligodentate ligands and the associated coordination geometries Mixed ligand chemistry is of particular interest and is an integral part of this discussion Various aspects... 2007 3:24 PM 2 Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications compounds A number of compounds have essentially the same activity, and this suggests the function is at a level not yet understood It seems quite likely that the insulin-mimetic effect derives from the simultaneous modification of the function of a number of enzymes and that the role of the ligands is to ensure... The quadrupole splittings are 200 Hz and 5.35 kHz for V1 and V4, respectively The spectrum was obtained from a tetradecyltrimethylammonium bromide (TDTMABr) mesophase of composition: TDTMABr, 160 mg; decanol, 30 mg; D2O, 450 mg; NaCl, 10 mg 46136_book.fm Page 18 Friday, February 16, 2007 3:24 PM 18 Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications Interestingly, if the salt... interest, as described by Equation 2.2 46136_book.fm Page 12 Friday, February 16, 2007 3:24 PM 12 Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications δh δl δ obs low pH high pH VL VLH P(VLH) = ( δ h - δ obs)/(δ h - δ l) - (PVL-) = (δ obs - δ l)/(δ h - δ l) SCHEME 2.1 In Scheme 2.1, P(VLH) and P(VL–) represent the molar fractions of the two species pH = log((δobs – δl) / (δh – δobs))... Ligands 51 4.3.1 β-Mercaptoethanol and Dithiothreitol .51 4.3.2 Bis(2-thiolatoethyl)ether, Tris(2-thiolatoethyl)amine, and Related Ligands 53 4.3.3 Cysteine, Glutathione, Oxidized Glutathione, and Other Disulfides 53 4.4 Amino Alcohols and Related Ligands 54 4.4.1 Bidentate Amino Alcohols and Diamines 54 4.4.2 Polydentate Amino Alcohols: Diethanolamine and. .. 16, 2007 3:24 PM 8 Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications evidence obtained for transient species to provide evidence for possible reaction pathways, for instance, for mechanisms of oxidation by peroxovanadates Vanadium-51 NMR spectroscopy is generally the method of choice for studying complex equilibria or obtaining structural data In principle, and frequently in . PM 4 Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications tidentate ligands such as aminopolycarboxylates are common ligands that. 2 Vanadium: Chemistry, Biochemistry, Pharmacology and Practical Applications compounds. A number of compounds have essentially the same activity, and