pneumocystis pneumonia in patients with inflammatory or autoimmune diseases usefulness of lymphocyte subtyping

Accepted Manuscript Title: Pneumocystis pneumonia in patients with inflammatory or autoimmune diseases: usefulness of lymphocyte subtyping Authors: Yi Li, Marc Ghannoum, Chuntao Deng, Yanxia Gao, Huadong Zhu, Xuezhong Yu, Valery Lavergne PII: DOI: Reference: S1201-9712(17)30056-5 http://dx.doi.org/doi:10.1016/j.ijid.2017.02.010 IJID 2877 To appear in: International Journal of Infectious Diseases Received date: Revised date: Accepted date: 5-11-2016 12-2-2017 13-2-2017 Please cite this article as: Li Yi, Ghannoum Marc, Deng Chuntao, Gao Yanxia, Zhu Huadong, Yu Xuezhong, Lavergne Valery.Pneumocystis pneumonia in patients with inflammatory or autoimmune diseases: usefulness of lymphocyte subtyping.International Journal of Infectious Diseases http://dx.doi.org/10.1016/j.ijid.2017.02.010 This is a PDF file of an unedited manuscript that has been accepted for publication As a service to our customers we are providing this early version of the manuscript The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain Pneumocystis pneumonia in patients with inflammatory autoimmune diseases: usefulness of lymphocyte subtyping or Running title: Lymphocyte subtypes in Pneumocystis Authors: Yi Li M.D.1, Marc Ghannoum M.D 2, Chuntao Deng M.D.3, Yanxia Gao M.D.4, Huadong Zhu M.D.1, Xuezhong Yu M.D.1, Valery Lavergne M.D.5 1.Emergency Department, Peking Union Medical College Hospital, Beijing 100730, China Nephrology Department, Verdun Hospital, University of Montreal, Montreal, Qc, Canada 3.Emergency Department, Shenzhen Luohu People's Hospital, Shenzhen, 518001, China Emergency Department, The First Affiliated hospital of Zhengzhou University, Zhengzhou 450052, China Medical Microbiology and Infectious Diseases Department, Sacré-Cœur Hospital, University of Montreal, Montreal, Qc, Canada Emails: Yi Li: billliyi@126.com Marc Ghannoum: marcghannoum@gmail.com Chuntao Deng: chuntao.deng@qq.com Yanxia Gao: gaoyanxiazzu@163.com Huadong Zhu: yyyyxx2010@gmail.com Xuezhong Yu: erxuezhongyu@sina.cn Valery Lavergne: valerylavergne@gmail.com Corresponding author: Dr Valéry Lavergne Hôpital du Sacré-Coeur de Montréal 5400 Boulevard Gouin Ouest Montréal, Québec, Canada H2V 3A5 Tel : 1-514-338-2222-7221 Fax : 1-514-504-1245 valerylavergne@gmail.com Word count: Abstract = 200 words Manuscript = 2986 words Tables = 5; Figure =1 Footnotes: (1) All authors have no commercial or other association that might pose a conflict of interest (2) This study was supported by the National Key Department Foundation of Health Ministry (No.2012-650 and 2012-649) The funding source had no role in the study design, the collection, the analysis and interpretation of data, the writing of the report nor the decision to submit the article for publication (3) The information has not been presented at a scientific conference (4) Dr Valéry Lavergne, Hôpital du Sacré-Coeur de Montréal, 5400 Boulevard Gouin Ouest, Montréal, Québec, Canada, H2V 3A5, tel : 1-514-338-2222-7221, fax : 1-514-504-1245, valerylavergne@gmail.com (5) No change in authors ‘affiliations and addresses since completion of the study Highlights  Lymphocyte subtyping is useful for predicting PcP and related mortality in non-HIV patients  CD3+ cell count