influence of cardiogenic shock with or without the use of intra aortic balloon pump on mortality in patients with st segment elevation myocardial infarction

Ờ Å ỊÙ× Ư Ờ Influence of Cardiogenic Shock With or Without the use of Intra-Aortic Balloon Pump on Mortality in Patients With ST-segment Elevation Myocardial Infarction Jesper Khedri Jensen, Per Thayssen, Lisbeth Antonsen, Mikkel Hougaard, Anders Junker, Knud Erik Pedersen, Lisette Okkels Jensen PII: DOI: Reference: S2352-9067(14)00095-5 doi: 10.1016/j.ijcha.2014.12.006 IJCHA 30 To appear in: International Journal of Cardiology Received date: Revised date: Accepted date: 19 April 2014 December 2014 20 December 2014 Please cite this article as: Jensen Jesper Khedri, Thayssen Per, Antonsen Lisbeth, Hougaard Mikkel, Junker Anders, Pedersen Knud Erik, Jensen Lisette Okkels, Influence of Cardiogenic Shock With or Without the use of Intra-Aortic Balloon Pump on Mortality in Patients With ST-segment Elevation Myocardial Infarction, International Journal of Cardiology (2014), doi: 10.1016/j.ijcha.2014.12.006 This is a PDF file of an unedited manuscript that has been accepted for publication As a service to our customers we are providing this early version of the manuscript The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain ACCEPTED MANUSCRIPT Cardiogenic Shock With or Without the use of IABP, J.K.Jensen IP T Influence of Cardiogenic Shock With or Without the use of Intra-Aortic Balloon Pump on Mortality in Patients With ST-segment Elevation Myocardial Infarction SC R Jesper Khedri Jensen MD PhD, Per Thayssen MD DMSci, Lisbeth Antonsen MD, Mikkel Hougaard MD, Anders Junker MD PhD, Knud Erik Pedersen MD DMSci, Lisette Okkels Jensen MD DMSci PhD NU Running title: Cardiogenic Shock and the use of Intra-Aortic Balloon Counterpulsation on Mortality CE P TE D MA Department of Cardiology, Odense University Hospital, Odense, Denmark AC Word count (total 4,563 including abstract, text, figure legends, tables and references) Correspondence to: Jesper K Jensen, MD, PhD, FESC Department of Cardiology Odense University Hospital Sdr Boulevard 29 5000 Odense C Denmark E-mail: jesperkjensen@dadlnet.dk Phone: +45 6541 2681 Fax: +45 6312 1730 ACCEPTED MANUSCRIPT Cardiogenic Shock With or Without the use of IABP, J.K.Jensen Abstract Background: Cardiogenic shock is a serious complication of a ST-segment elevation myocardial T infarction (STEMI) We compared short- and long-term mortality among (1) STEMI patients with IP and without cardiogenic shock and (2) STEMI patients with cardiogenic shock with and without the SC R use of intra-aortic balloon pump (IABP) Methods: From January 1, 2002 to December 31, 2010, all patients presenting with STEMI and NU treated with primary percutaneous coronary intervention (PCI) were identified The hazard ratio (HR) for death was estimated using a Cox regression model, controlling for potential confounding MA Results: The study cohort consisted of 4,293 STEMI patients: 286 (6.7%) with and 4,007 (93.3%) without cardiogenic shock Compared with patients without cardiogenic shock, patients with D cardiogenic shock were older, and more likely to have diabetes mellitus, multi-vessel disease, TE anterior myocardial infarction (MI) or bundle-branch block MI and a reduced creatinine clearance CE P Among patients with cardiogenic shock vs without shock, 30-day cumulative mortality was 57.3% vs 4.5% (p