363 cancer gene therapy by intravenous administration of naked plasmid encoding interferons

363 Cancer Gene Therapy by Intravenous Administration of Naked Plasmid Encoding Interferons Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society of Gene Therapy[.]

APPLICA TION OF CHEMOKINES IN IMMUNOTHERAPY PPLICATION , J%" (!898;  ,  I             " $:J(!898;   & @!",                ?*               &9 @!",   0 $*'                  "   ?*   $:J              1     "            $*'      (!898; '   (!898;            "           3                              E  " #@" "" 360 Improved T reatment of Pancreatic Cancer by ILTreatment 12 and B7.1 Costimulation: Immunoregulation and Anticancer Efficacy in a Non-Immunogenic T umor Model Tumor Florian Rodicker,1 Mary M Hitt,2 Thorsten Stiewe,1 Brigitte M Putzer.1 Centre for Cancer Research and Cancer Therapy, Institute of Molecular Biology, University of Essen, Medical School, Essen, Germany; 2Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada $                             $                            "                     -' /     3     "8, -D"8,/          2;8  3                       C    3        D"8,   2;8       "                ' D"8,           E   ' D"8,%2;8                        :9H      (   H         "                                           #C      '!8 3          - '!,D#!, D#!;/              ' D"8,%2;8            "         (      !48::%,"8%,",     $  ?    361 Regression of T umor Growth and Induction of Tumor erm Antitumor Memory by IL-12 Electro-Gene Long-Term Long-T Therapy Shulin Li.1 HFHS )E  7 ! "              3                  C                          E      $                                                  E      "8, -D"8,/                        #  7 ' 1     -(/   D"8,                                       *                            D"8,   "     @ 7           ,9   D"8, $*'        69H    C               T88   )               D" 8,   "          D"8,"   "     " -?*"/       ?*"-#/           89 -!"89/        Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy             $:J "  -!O99&/ 7 D"8,   "                            ' "                   D"8,   "                    D" 8,   "                                       "         " "  ( 362 Local and Systemic Effects of an Allogeneic Tumor Cell V accine Combining T ransgenic Human Vaccine Transgenic Lymphotactin with Interleukin-2 in Patients with Advanced or Refractory Neuroblastoma Ettore Biagi,1 Raphael F Rousseau,1 Ann E Haight,4 Eric S Yvon,1 Donna R Rill,1 Zhuyong Mei,1 Edwina Popek,3 Laura C Bowman,4 Malcolm K Brenner,1 Douglas Strother.2 Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, United States; 2Texas Children′s Cancer Center, Baylor College of Medicine, Houston, TX, United States; Department of Pathology, Baylor College of Medicine, Houston, TX, United States; 4Hematology-Oncology, St Jude Children′s Research Hospital, Memphis, TN, United States >      "           ",                              C            3        -D/ "  " "     "     ", -D",/     "      E  '                 G          3              "                  D"   D","                   ,8              (                &         8 E "                    $6J   $:J   (           3  $6J " -=&B±&6%μB5:±,8;%μ,"    ! 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M 996,/ (3           *A   ?    8;                 G            $6J "       3 '   :"   ,                    ,           ,;                      8,   '           &          5                         D  D",                "                 D",   '              " 3                                           363 Cancer Gene Therapy by Intravenous Administration of Naked Plasmid Encoding Interferons Naoki Kobayashi, Takeshi Kuramoto, Shi Chen, Yoshihiko Watanabe, Yoshinobu Takakura    -?*/ 3                                       E    ?*                   C        ?*            3     "       S119 APPLICA TION OF CHEMOKINES IN IMMUNOTHERAPY PPLICATION $*' -$*'/        3                                  "                 $*'  ?*"  ?*"  $*'                                 E  -     /    E  -    /     E  -     /         ",B   2   ?*"          ?*    3                   7                    ?*                         ?*" 3  $*'                     '      $*'                       (                           ?*"  " 3  $*'      ?*"" 3  $*'    )         ",B             $*'                 "    $*'                      3        364 Naked DNA Gene T ransfer of IL-12 Prevents Transfer Angiogenesis and Angiogenic T umor Growth In V ivo Tumor Vivo Independently of IFN Gamma Adriana Albini,1 Monica Morini,2 Girieca Lorusso,2 Michele Cilli,3 Silvano Ferrini,4 Karin Mölling,5 Douglas M Noonan.2 Laboratory of Molecular Biology, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy; 2Tumor Progression Section, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy; Animal Facility, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy; 4Immunopharmacology Section, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy; 5University of Zurich, Zurich, Switzerland D8,                    *A              "    D"8,                       ?*"       *A      1  !" 89 0   $*' " E    3          , D"8,             D"8,                '          E               -   A(      >?% *?    /      '  6             3    G                 E             E        D" 8,   E            D"8,                  E     D"8, 3       ,      ,9               "   &;%                            E     D"8, 3                ,                          *A    &;%      *A  "        "   D"8,              ?*  "      ?*                     ? D"8,   $*'                   A("                  "               A( S120 365 Upregulation of NK Functions Underlies the Efficacy of Intratumorally Injected Dendritic Cells Engineered to Produce Interleukin-12 Mercedes Rodriguez-Calvillo, Marina Duarte, Iñigo Tirapu, Pedro Berraondo, Guillermo Mazzolini, Cheng Qian, Jesus Prieto, Ignacio Melero E       -$/               D"8,   3         1                    $:J "             1                $6J "                     *A      "'#8                                         *A          $            $6J   *A                           *A           E     $         "   2"    -@8"%"/        *A    $               D"8,               *A      D"8,       1 1   >1   $       *A             D"8,    $ E          @8"%"         *A                D"8, )               *A                    E   D"8,"   $    *A                  D"8, 366 Complete Rejection of Metastatic Lymphoma in Murine Liver by In V ivo T ransduction with IL-21 and IL-15 Vivo Transduction Genes Tsunao Kishida, Hidetsugu Asada, Feng-De Cui, Jiro Imanishi, Osam Mazda Department of Microbiology, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, Japan                          @      -D/",8             γ -D",@ γ /               D",8@ D",8     3           -*A/             3       "   "$= D"8&    1  γ                 *A     *A        *A    D",8   D"8&                   "         >  2    ->2./"                     3        C          "                     >2."      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