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PATIENT-CENTERED OUTCOMES RESEARCH INSTITUTE ® 1828 L STREET NW, SUITE 900 WASHINGTON, DC 20036 202.827.7700 PCORI funds research to help patients choose healthcare options that best meet their needs AWARDEE AND COMMUNITY PARTNERS STATE PORTFOLIO Missouri 24 INCLUDE $ PROJECTS • Asthma and Allergy Foundation of America, St Louis Chapter 42 • Boys and Girls Clubs of Greater St Louis • Faith Works Connecting for a Healthy Community MILLION AWARDED * • Ferguson-Florissant School District • Heartland Primary Care • Mercy Children’s Hospital St Louis *Including 10 research projects and 14 awards that support engagement in research As of December 2019 • St Luke’s Hospital of Kansas City • University of Missouri, Kansas City • Washington University in St Louis STUDY SPOTLIGHT: DEPRESSION • Washington University School of Medicine in St Louis Comparing Treatments for Older Adults with Major Depression More than half of older adults who are diagnosed with major depression don’t get better even after trying two or more antidepressants This study is comparing how well different types and combinations of medicines work for adults aged 60 and older who have treatment-resistant depression The study is based at Washington University School of Medicine CONDITIONS STUDIED INCLUDE Asthma Cardiovascular Disease WWW.PCORI.ORG/STATEPORTFOLIOS Depression | WWW.PCORI.ORG Rare Diseases | INFO@PCORI.ORG Reproductive and Perinatal Health | FOLLOW US @PCORI PROJECTS FUNDED IN MISSOURI ARE: RESEARCH PROJECTS Comparing Treatments for Older Adults Who Have Major Depression That Does Not Respond to First-Line Antidepressant Medicines Washington University School of Medicine in St Louis $13 M Posterior Fossa Decompression with or without Duraplasty for Chiari Type Malformation with Syringomyelia Washington University School of Medicine in St Louis $2.8 M Comparing Two Ways to Manage Asthma in African-American Children Washington Universityin St Louis $2.3 M Improving Provider-Patient Communication to Reduce Antibiotic Misuse Mercy Children’s Hospital St Louis $2.1 M Implementation of Patient-Centered Contraceptive Provision in Community Settings Washington University School of Medicine in St Louis $1.8 M Patient-Centered Outcomes Recovery from Treating Peripheral Arterial Disease: Investigating Trajectories St Luke’s Hospital of Kansas City $1.8 M Developing and Testing a Personalized, Evidence-Based, Shared Decision Making Tool for Stent Selection in Percutaneous Coronary Intervention University of Missouri,Kansas City $1.7 M Developing and Validating Quantitative Measures to Assess Community Engagement in Research Washington UniversitySchool of Medicine in St Louis Learning What Matters Most to Patients with Peripheral Artery Disease St Luke’s Hospital of Kansas City $640,000 Incorporating Genetics into Patient-Centered Outcomes Research: An Engagement Model for the Autism Research Community Mercy Children’s Hospital St Louis $250,000 Community Collaboration toward Reducing Health Disparities in St Louis-Area Youth University of Missouri, St Louis $250,000 Training Journalists in Evidence-Based Medicine, Comparative Effectiveness Research, and Health Data Center For Excellence In Health Care Journalism $150,000 Relieving Pain in Kansas City (Tiers I, II, and III) Center for Practical Bioethics $90,000 Engaging Communities in Infectious Diseases Research and Intervention Development (Tiers I, II, and III) Mercy Children’s Hospital St Louis $90,000 Traumatic Brain Injury Treatments for Veterans A.T Still University of Health Sciences $50,000 Incorporating Genetic Data in Patient-Centered Outcomes Research Studies Mercy Children’s Hospital St Louis $50,000 Finding Effective Community Solutions to Increase Colon Cancer Screening Among African Americans (Tiers I and II) Faith Works Connecting for a Healthy Community $40,000 $1 M ENGAGEMENT IN RESEARCH PROJECTS UPDATED DECEMBER 2019 | RESEARCH DONE DIFFERENTLYđ â 2019 Patient-Centered Outcomes Research Institute All Rights Reserved

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