CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE

1 2 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 VERBATIM PROCEEDINGS CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 1:02 P.M 805 BROOK STREET ROCKY HILL, CONNECTICUT POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 Continued verbatim proceedings of the Connecticut Stem Cell Research Advisory Committee, held at 805 Brook Street, Rocky Hill, Connecticut, on June 17, 2008 at 1:02 p.m CHAIRPERSON JULIUS LANDWIRTH: For the record, my name is Julius Landwirth, and I’m substituting 10 for our Chair, Dr Galvin, who is away, and I will be 11 taking that position until about 3:00, when I have to 12 leave 13 14 MR ROBERT MANDELKERN: Julie, louder, CHAIRPERSON LANDWIRTH: It will be taken please 15 16 over at that point by your friend, Milt Wallack 17 not yet have a quorum, but we have a guest speaker, who 18 we’re anxious to hear from, who is on a tight schedule of 19 his own, so I suggest that we proceed with that part of 20 it 21 It doesn’t require taking any official action Now this is the first time that we’ve had We POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 a guest speaker from this perspective at our meeting, so I’d just like to, before he’s formally introduced, ask Warren to just give us a little background information, as to how we got to this point MR WARREN WOLLSCHLAGER: Thank you very much, Dr Landwirth a few of the meetings of the Interstate Alliance on Stem Cell Research legislation and/or existing publicly funded stem cell We reported back a few times now on That’s the body of states with enabling 10 programs that get together every six months for purposes 11 of increasing collaborative opportunities 12 We had a meeting Our most recent meeting 13 was in March down in D.C., and that was also the first 14 time that we brought in members of the advocacy 15 communities, patient advocates and invited them to present 16 their priorities and issues to all the states who were 17 gathered around 18 We’re very pleased that Dr Goldstein was 19 able to come and talk to us about current and planned 20 activities at the JDRF 21 states to discuss with him opportunities for He put out an offer to other POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 4 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 collaboration Goldstein today, so we’re pleased it’s working out That led to this body inviting Dr I know, for a more formal invitation, I’m going to turn it over to Dr Fishbone DR GERALD FISHBONE: Chief Scientific Officer for the Juvenile Diabetes Research Foundation, and he’s responsible for guiding and supervising all of the research portfolio for the foundation Dr Goldstein is the He has an M.D degree, a Ph.D degree, an MBA 10 degree, so he has a pretty good background for many 11 things 12 He was, prior to coming to JDRF in 1997, 13 he was Director of the Division of Allergy, Immunology and 14 Transplantation at the National Institute of Allergy and 15 Infectious Diseases at the NIH 16 He’s written many papers, is on the 17 Advisory Boards of many committees, but I think one of his 18 major interests is in Stem Cell research, where he has 19 been the point man for the Juvenile Diabetes Research 20 Foundation since the very advent of Stem Cell research and 21 has been following very closely all of the things, the ups POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 and downs of what’s happened and, also, has some insights into the possible future of it DR ROBERT GOLDSTEIN: you very much Can you hear me? MR MANDELKERN: amplification Dr Goldstein? Thank you Thank Does this work? No That’s not That’s just for the record DR GOLDSTEIN: That’s just for him? Can you hear me? MR MANDELKERN: Yes 10 DR GOLDSTEIN: Okay Do you mind if I 11 sit, as opposed to stand? 12 you for inviting the Juvenile Diabetes Research Foundation 13 to spend a few minutes with you 14 Embryonic Stem Cell wars since 1998, when we were one of 15 the very, very first foundations that took a public 16 position and said this is a good thing for our 17 constituency, and that led to a variety of things 18 Does that work? Okay Thank We’ve been at the Human Now, as we blink an eyelash, 10 years has 19 passed, and I guess, to some extent, we’re still at this 20 What I’ve come here today is really I’ll give the 21 conclusion first Partnering and collaborating is, we POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 think, key to stem cell research, if not, other areas of science effort, whether it be with a foundation like us, or whether it be with another state It’s begging for this kind of collaborative We think we have some good experiences to share with people on the one hand, and, on the other hand, we like to this kind of thing, because we want to get you to our work, and we’d like to find out what it would take to accomplish that 10 The first slide is a commercial message, 11 which says something that is important from my 12 perspective 13 years ago by really moms and pops 14 they raised 10,000 dollars and funded research and said 15 their mission would be to raise money and cure this 16 disease 17 This organization was founded more than 30 In the first year, It didn’t work out on their time frame 18 We’re still at that 19 June 30th, which is why I’m rushing back, it’s the end of 20 fiscal year, so you all understand what that means, we’ll 21 fund about 160 or 165 million dollars’ worth of research In this current year, which ends POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 this year, and we project 195 million spent next year Of that, probably 10 million or so would be on stem cell in all aspects, so that makes us a fairly important source of funds for research and diabetes, Juvenile Diabetes and stem cell Next slide? Next one? This slide just outlines what I would call some of our operating principles, which we don’t have to belabor, but, basically, from the beginning, we supported very basic 10 work 11 other, and we created the typical environment of sharing 12 information these days, so when we give people grants, we 13 tell them we want to share data, we want publications out 14 We support people working and talking with each The recurring theme is that the 15 collaboration has been extraordinarily important and 16 interdisciplinary work much discussed, but seldom done and 17 practiced in the states 18 public education and that sort of thing We try to our fair share of 19 Because of the politics of stem cell, 20 we’ve got our fair share, also, of trying to educate 21 legislators, and I’m sure that our local JDRF people POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 worked hard to get the Connecticut Stem Cell initiative going Next, please? This is just a snapshot of funding little more funding three or four years ago, but one of the benefits of having state initiatives has taken some pressure off the foundation, in terms of where we send our money Actually, this slide would have shown probably a To underline that, we’ve actually shifted, 10 whereas five or 10 years ago we supported the creation of 11 more stem cell lines of dissemination, a variety of 12 information 13 translation end of the spectrum 14 Today, we’ve really shifted to the We know others have done all of the 15 legwork and all the hard work 16 work is taking those stem cells and making, in our case, 17 insolence of creating cells, or close to that, and then 18 having a crack at really treating many people with 19 diabetes 20 21 Next? on this Now the rest of the hard I don’t need to spend a lot of time When we started funding stem cell research, POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 there were no national guidelines Bioethics Commission Sciences There was no National There was no National Academy of We created our own version That served as a model for many organizations Academy of Sciences a few of the names, people like Bernie Low(phonetic), Jim Shildres(phonetic), Eric Meslin(phonetic), who served on the original NIH work, Austin Smith, Ron McKie(phonetic) 10 It’s a template right out of the National In the next slide, just to highlight We knew we had to have a squeaky clean 11 supervisory group that were recognized by the community as 12 being, you know, respectable people 13 admission was, and nobody gets compensated, by the way, 14 but the ticket of admission was very simple 15 The ticket for We did not invite people to rediscuss 16 whether or not human embryonic stem cell research was a 17 proper avenue for the foundation, but, rather, to discuss 18 assuming that you were going to that, how you 19 it under the highest ethical standards, etcetera 20 Next? 21 a lot of activities We have, at any one moment in time, The most recent, we’ve had a POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 10 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 research funding announcement requesting applications for networks, as well as applications for individual grants, which we’ve recently funded In addition, on the next slide or the one after this one, I review our partnerships, because I think these help to drive a worldwide agenda JDRF spends about a third of its research funds outside the United States Just so you know, It’s quite unique among typical disease 10 oriented foundations in the United States, because most 11 places donors require them to spend their money locally, 12 whether within the walls of the United States, or, in the 13 case of state initiatives, within the walls of the state, 14 which we all understand the reasons for that, but that 15 creates some obstacles, in terms of how you go about doing 16 the research, the actual research in the most productive 17 manner 18 Our research model says that we want to 19 support the very best research that we can find to 20 accomplish the task wherever it’s located, and it doesn’t 21 matter to us whether it’s an academia or industry POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 Your 119 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 or the grant has to be approved by the ESCRO committee? DR KIESSLING: It has to be approved before it could be funded DR WALLACK: All right, so, there’s a motion to go forward with the funding of the 900,000 dollars, contingent on it being approved by the ESCRO of whichever institution you choose to work with, and I think I’ve heard you say you’re probably leaning towards UConn, but that’s not probably relevant right now 10 DR WU: I just have one thing I want to 11 mention 12 part is for nuclear transfer training in which we will use 13 animal eggs and animal cells, just to train the nuclear 14 transfer technology 15 funded to start work without the part 16 17 18 That is, in this core facility grant, a large I’m wondering if that portion can be Of course, the part where it involves human eggs we’ll have to get ESCRO approval DR WALLACK: My understanding of what we 19 have to with this is have a teleconference to go 20 forward with any part of the project, so my 21 interpretation, unless, Marianne, I’m wrong, is that we POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 120 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 can’t fund any lesser portion project, which will happen, if it does happen, at that teleconference that Dan has alluded to MR MANDELKERN: We have to fund the entire I second Dr Fishbone’s motion DR WALLACK: Second to the motion That motion also will now be tabled with a motion on the floor Okay have to on six, if I’m not mistaken 10 11 Dan, I think that we’ve gone through everything we MR WAGNER: Yeah I can update the 2008 contracts right now, number 10 12 DR WALLACK: Dr Canalis first, please 13 DR CANALIS: How you insure that 14 before you release funds, you require proof of IRB and 15 ESCRO review and approval? 16 MR WAGNER: 17 DR CANALIS: You require evidence of MR WAGNER: I have originals or PDFs of 18 19 Yes that? 20 signed letters from the ESCRO committees, so UConn has one 21 committee for both campuses, and Yale has their own POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 121 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 committee, also, so we have that DR WALLACK: MR MANDELKERN: Bob? I’m just curious about this item, which has not been handled, on the 2008 grant issues, 08 SCC YSME 05, Redmond revised budget needs to be approved according to the e- mail from CI on Friday MR WAGNER: Yeah It has passed ESCRO, and Dr Fishbone was the reviewer, and I’m not sure if so we were, as we did 10 last meeting, the reviewers provided an update, and then 11 make a recommendation, in terms of passing the revised 12 budget or not 13 I don’t know if you could comment on that DR FISHBONE: Yeah Let me just get to 14 it 15 1,999,000, 1,999,514, and we approved 1,120,000, and Dr 16 Redmond sent a letter to Dan, saying that what they have 17 done is they have an assurance from Axion Research to 18 support the non-state and non-federal funding 19 raise the money for the portion done in St Kitts 20 reduced the budget by eliminating a staff member and 21 replaced by personnel there, and a postdoctoral fellow The original budget for the Redmond grant was POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 They will They 122 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 will be funded from another non-federal private donation In addition, some genomic studies reduced in scope during the final one and a half years, and they believe that the project can be successfully concluded in three and a half instead of four years, so they responded to all of the questions that we have I think satisfactorily The only one that I don’t have an answer to was that the Yale ESCRO committee was meeting on May 10 5th to review the proposal, and I not know the results 11 12 MR WAGNER: And they have approved that grant at this point, yes 13 DR FISHBONE: 14 MR MANDELKERN: 15 They have approved, yeah mail 16 MR WAGNER: 17 MR MANDELKERN: 18 19 20 21 It’s recorded in the e- Yeah It’s recorded in the e- mail the ESCRO has approved it MR WAGNER: So they’re all set with that I received the paperwork and the verification letter DR FISHBONE: So I would make a motion to POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 123 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 fund the grant, the 1,120,000, with the explanations in place DR WALLACK: Is there a second to that motion? MR MANDELKERN: DR WALLACK: Second And is there a motion to table again? I second that motion MR MANDELKERN: Yes It has to table There’s no quorum 10 DR WALLACK: Right, so, we will table 11 that, also 12 All right, so, you want to go back down to 10 at this 13 time, Dan? 14 Thank you All right, so, thank you, Gerry MR WAGNER: Yeah So the contracts we’ve 15 received all the paperwork and all the ESCRO from all of 16 the grants, except for Carter, Rasmussen and the Lee grant 17 that we just heard about, and Redmond is the fourth one 18 that we were waiting approval of the budget 19 All the other grants have been sent out to 20 the universities for review and signature, so we should be 21 getting that back, and I believe we’ve requested the money POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 124 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 to be allocated for that, pending DPH approval, so we’re moving forward with the 08 grants The 06 grants, all the revised financial reports have been received, I believe outstanding, one or two, and we’ll collect those up this week and get those to DPH to review, and then, hopefully, we’ll have release of funds for the second year for the 06 grants, so everything is moving along 10 I assume that, by the end of the month, everybody will have their dollars, I’m hoping 11 DR WALLACK: 12 MR WOLLSCHLAGER: 13 Maybe there’s one Any discussion? Just if I can add to that? 14 DR WALLACK: 15 MR WOLLSCHLAGER: Yup I think I have an e- 16 mail from our business office, saying the DPH fiscal 17 concerns were addressed 18 MR WAGNER: 19 MR WOLLSCHLAGER: 20 21 that with you Okay I believe I’ve shared There may be one outstanding DR WALLACK: Any other discussion? POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 125 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 MR WAGNER: The only thing else is the strategic planning DR WALLACK: No Before we get to that, before we leave 10, can we request that a reminder note go to those other three? MR WAGNER: DR WALLACK: MR WAGNER: 10 DR WALLACK: 11 MR WAGNER: Yup Great Okay To the two people that would not be here, so these guys know where they stand 13 DR WALLACK: 14 MR WAGNER: 15 Oh, you sent them out already? 12 I sent them out yesterday Okay The other two, Carter and Rasmussen, were e-mailed, and they’re aware 16 DR WALLACK: So if we could include it, 17 for the record, that that’s been done, that would be 18 great 19 MR WAGNER: 20 DR WALLACK: 21 report, Ethics and Law Yup Okay You’ve got the Oh, he walked out POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 Mike Genel 126 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 was at the strategic planning on the strategic planning update, please? Can I turn, Warren, to you MR WOLLSCHLAGER: Sure Dr Latham came down sick, actually, at the last minute today, so he asked that we give an update We had a non-committee meeting, just a group of interested people got together a couple of weeks ago, discussing a strategic planning process, sort of revisited some of the issues raised by this committee, as 10 well as by CASE in their phase one report 11 The attendees included Dr Genel, Dr 12 Wallack, Paul Piscatello 13 there? 14 the original report 15 wasn’t able to make it 16 Myself I don’t know Who else was And Rick Strauss from CASE to talk about Bob Mandelkern was invited, but Basically, there’s a couple of points that 17 Dr Latham wanted to bring forward 18 believe that there should be strategic planning efforts in 19 place, both short-term and long-term, short-term to 20 identify anything that might require legislative attention 21 in the upcoming session, the long session, and longer term One was that he does POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 127 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 to look at some of those issues that were already identified in the CASE report The group was talking about looking to some non-biased, or, you know, clean entity to be working on that type of strategic planning on behalf of the committee, rather than going to anyone that’s currently funded, any institution that’s currently funded The other thing was that Steve was going to recommend formally that Paul Piscatello assume 10 chairmanship of the Strategic Planning Committee, and Dr 11 Piscatello agreed to that, but that’s a point of 12 information now 13 absent the chair 14 There’s not really much that we can I threw out an e-mail earlier this week 15 that I think it would be critical that Connecticut 16 Innovations participate in any strategic planning process, 17 as well, since their role will continue to be increasingly 18 complex over time as we get more and more annual, you 19 know, reports going on and juggling contracts at the same 20 time 21 joining that group I think CI is willing or at least interested in POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 128 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 I don’t know if anybody else was at the meeting and has anything else to say DR WALLACK: Mike, any comments from the strategic planning process that you’d like to add? DR GENEL: Well, no I think Warren gave a pretty comprehensive, succinct summary in his usual fashion have Connecticut Innovations participating in this I agree I think that it was very helpful to On a long-term basis, I think what we were 10 trying to wrestle with is the long-term future of the 11 research program in Connecticut and whether or not there 12 may be some benefits in connecting it with other research 13 funding programs that are in place in Connecticut 14 particular, there is one funded out of DPH that is 15 supported by tobacco funds, and it seemed to us that 16 they’re creating some sort of cohesion perhaps under a new 17 entity might make some sense, but need to be carefully 18 considered 19 20 21 Obviously, the fiscal climate in the state at the moment is not optimal for that DR WALLACK: Thank you very much In POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 Target 129 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 dates Marianne, Warren, what was that supposed to be about? MR WAGNER: particular think we had any We usually have it at the bottom, but I don’t MR WOLLSCHLAGER: Mr Wagner likes to have target dates I don’t think we had any in DR WALLACK: Okay, so, there’s nothing we have to do? 10 MR WAGNER: No I think we’re just 11 wrapping up loose ends at this point and trying to get the 12 money 13 14 MR MANDELKERN: pardon me So are we scheduled Are we scheduled for 7/15? 15 MR WAGNER: I think we should leave it on 16 the schedule, if possible We have a number of things 17 that we have to vote on still, and if we’re not able to 18 get that telephone conference scheduled with the entire 19 committee to vote on UConn and Yale grants, then we’ll 20 definitely need that, because we don’t want things waiting 21 off until POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 130 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 DR WALLACK: Why don’t we anticipate being able to the teleconference to complete this whole granting process? MR WAGNER: I can send e-mails out tomorrow morning, trying to get dates on people, but we need seven of the nine that can vote on Yale, and we need the rest of the people, so, I mean, everybody is traveling this week people that just came back last week, people are going off 10 There’s bios out in San Diego, on trips, Paul is in Beijing 11 DR WALLACK: Right People on vacations 12 That’s going to be a little difficult 13 that you keep the July 15th on target 14 MR WAGNER: 15 DR WALLACK: 16 MR WAGNER: Because by the time you We might be close to the 15th 19 DR WALLACK: 20 MR WAGNER: 21 Yup finish with trying to find a date 17 18 I would recommend It may be the 15th Okay And it could be a short meeting, but we just need to clarify those points POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 131 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 DR WALLACK: Right, but I would also recommend that you try to get a date prior to that doesn’t work, it will have to be the 15th MR MANDELKERN: Excuse me, Milt If it I would recommend strongly that we don’t wait until the 15th Here it is the June meeting, and we don’t have any kind of a quorum close to it call, and it has to be done quickly It has to be done by conference DR KIESSLING: 10 subject of the e-mail 11 a date 12 Dan, put a date in the Say, please respond by and give us DR WALLACK: Right Good idea Thank 13 you 14 anybody else wants to bring up under new business? 15 not, public comment 16 All right Is there any other agenda items that I’m sorry MS PAULA WILSON: If Paula? I just have one 17 question, or two questions 18 the 2008 awards, number one, and, number two, is there any 19 information coming forward whether there will be another 20 RFP coming out this fall? 21 MR WAGNER: Do you have a start date for The first one, I think, on POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 132 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 the contracts that were sent out, I think we have a date of MS CHELSEY SARNECKY: The 20th to get the contracts back to CI MR WAGNER: The start date will be when we receive them and when our president signs them, okay? So we will try to collect as many as possible and have them kick off as soon as possible on that same date, so we’re not having two months of reviews 10 11 And in the second point, I don’t know if we’ve talked about the RFP at this point 12 13 MR MANDELKERN: question 14 MR WAGNER: 15 MR MANDELKERN: 16 MR WAGNER: 17 DR WALLACK: 18 Yeah Is it not, Dr Wallack? It has not come up Is that okay, Paula? MS WILSON: 20 DR WALLACK: Will the RFP question -Marianne, can we put down the continuation of the RFP question in answer to Paula’s Are you all set? 19 21 That’s a committee POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 133 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 question that we can bring up hopefully on the next agenda item? MS HORN: DR WALLACK: Yes Thank you Okay If there’s no other public comments, is there a motion to adjourn? MR MANDELKERN: DR WALLACK: MR WAGNER: 10 All in favor? Please pick up after yourselves 11 12 So moved (Whereupon, the hearing adjourned at 3:42 p.m.) POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 ...1 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 Continued verbatim proceedings of the Connecticut Stem Cell Research Advisory Committee, held at 805 Brook... advent of Stem Cell research and 21 has been following very closely all of the things, the ups POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE. .. POST REPORTING SERVICE HAMDEN, CT (800) 262-4102 RE: CONNECTICUT STEM CELL RESEARCH ADVISORY COMMITTEE JUNE 17, 2008 think, key to stem cell research, if not, other areas of science effort, whether