... cytotoxic drugs by increasing the sensitivity of the tumors to these agents Indeed, it has been shown that PARP-1 inhibitors not only significantly enhance the anti-tumor efficacy of the alkylating ... mice are viable and healthy [32], and inhibitors that are specific for PARP-1 are relatively non-toxic and not directly damage DNA, PARP-1 inhibitors might be both safe and...
Ngày tải lên: 31/10/2012, 16:57
... the duration of the effect depends on the rate of enzyme resynthesis Furthermore, salicylate may contribute to the effect ASA irritates the gastric mucosa (direct acid effect and inhibition of ... secretion PG promote the production of gastric mucus and reduce the formation of gastric acid (p 160) Menstruation PGF2! is believed to be responsible for the ischemic ne...
Ngày tải lên: 24/10/2013, 19:15
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... Cmax, giảm dao động hấp thụ thuốc ảnh hởng thức ăn tăng 25% sinh khả dụng Mong thông tin cập mang lại niềm vui cho bệnh nhân bị rối loạn lipid máu Tài liệu tham khảo Tài liệu khoa học công ty dợc ... đợc pha lipid thành mạch, vitamin E chống chọi với oxy hoá LDL chống tác hại gốc tự nội bào * Bình rợu cũ Fenofibrat (liphanthyl) từ lâu đợc dùng phổ biến để điều chỉnh ng...
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Programmatic update Use of Antiretroviral Drugs for Treating Pregnant Women and Preventing HIV Infection in Infants pptx
... resistance in women due to poor adherence and in infants infected despite maternal ART, and the acceptability and feasibility for women of remaining in care and on lifelong ART, especially for women ... drugs for treating pregnant women and preventing HIV infections in infants: recommendations for a public health approach, 2010 version Geneva,...
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Guidance for Industry Acute Bacterial Sinusitis: Developing Drugs for Treatment ppt
... Guidance for Industry Acute Bacterial Sinusitis: Developing Drugs for Treatment Additional copies are available from: Office of Communications, Division of Drug Information Center for Drug ... 17 Contains Nonbinding Recommendations Guidance for Industry1 Acute Bacterial Sinusitis: Developing Drugs for Treatment This guidance represents the Food and D...
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Báo cáo y học: "clinical review: Devices and drugs for cardiopulmonary resuscitation – opportunities and restraints" pot
... waveforms and allow lower energy defibrillation, which minimizes myocardial injury and the severity of the newly identified condition ‘postresuscitation myocardial dysfunction’ [13,14] Postresuscitation ... progressively impaired over an interval of hours, with gradual recovery over the following days [20] The severity of postresuscitation myocardial dysfunction is minimized by early res...
Ngày tải lên: 12/08/2014, 20:20
Liposomal co encapsulation of quercetin with synergistic chemotherapeutic drugs for breast cancer treatment
... Effect of cholesterol on quercetin incorporation Effect of incorporation of mol% of DSPE-PEG 0 on the incorporation of quercetin 50 4.2.3 Influence of different lipids on quercetin incorporation ... develop a liposomal formulation to solubilize quercetin, (ii) identify chemotherapeutic drugs that synergize with quercetin in breast cancer cells, (iii) co- enca...
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Enantioseparation of beta blocker drugs for pharmaceutical applications
... nature of chiral drugs The thermodynamic properties of enthalpy, entropy and Gibbs free energy of formation of racemic compound of propranolol hydrochloride and the entropy of mixing of the (R)-, ... 8.21 ∆H Enthalpy of formation of racemic compound ∆H Enthalpy of fusion of racemic compound f ∆H lm Enthalpy of mixing of enantiomers in the liquid state ∆H sm Enthalp...
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Knowledge representation and ontologies for lipids and lipidomics
... Knowledge representation and ontologies for lipids and lipidomics Low Hong Sang (B.sc.(Hons), NUS) Thesis Submitted for the degree of Master of Science Department ... nomenclature, lipids are divided into major categories, namely the fatty acyls, glycerophospholipids, glycerolipids, sphingolipids, sacharrolipids, sterol lipids, prenol lipids and the polyketides ... pe...
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Tài liệu The Acquisition of Drugs and Biologics for Chemical and Biological Warfare Defense - Department of Defense Interactions with the Food and Drug Administration doc
... recipients of IND drugs, medical monitoring and reporting of the use of such drugs, information about shipment and storage of drugs, disposition of unused IND drugs, and submission of annual and other ... changes in the Office of the Secretary of iii iv The Acquisition of Drugs and Biologics for CBW Defense Defense (OSD) to centralize the au...
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... the effectiveness of the PRECEDE education model on the changes in HbA1c, blood pressure (BP), lipids, and body mass index (BMI) in patients with DM2 over the long-term (2 years) Methods Patients ... http://www.biomedcentral.com/1471 -24 58/11 /26 7/prepub doi:10.1186/1471 -24 58-11 -26 7 Cite this article as: Salinero-Fort et al.: Effectiveness of...
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