... guidance on ARVs for preg- nant women, planned for release in early 2013. 1 Antiretroviral drugs for treating pregnant women and preventing HIV infec- tions in infants: recommendations for a public ... both for PMTCT and as the first-line national ART regimen for non-pregnant individuals. The ability to use the same regimen for PMTCT and for first-line ART considerably simplifies drug forecasting, ... pregnant women) on ART for life for their own health as well as for the prevention of infant HIV infection. For women with CD4 counts >350 cells/mm 3 , who are not eligible for treatment according...
Ngày tải lên: 08/03/2014, 15:20
... non-responsive to the treatment. It was therefore proposed that PARP-1 inhibitors might be the long-sought genetically specific drugs that are both safe and effective for treating BRCA1/2- associated breast ... [8-15]). Hence, BRCA1 is essential for maintaining genome integrity while genetic instability associated with BRCA1 deficiency is responsible for breast cancer formation [16, 17]. One of the ... BRCA1/2-associated breast cancers and discuss possible options for using these drugs efficiently. 2. PARP-1 inhibitors as potential chemotherapeutic drugs Using a clonogenic survival assay, Bryant et...
Ngày tải lên: 31/10/2012, 16:57
PERFORMANCE OF A COMBINED CONSTRUCTED WETLAND SYSTEM FOR TREATING VILLAGE SEWAGE IN LAKE DIANCHI VALLEY
Ngày tải lên: 05/09/2013, 08:40
Color Atlas of Pharmacology (Part 18): Drugs for the Suppression of Pain
... such as tinnitus, vertigo, drowsiness, etc. The search for better tolerated drugs led to the family of non- steroidal antiinflammatory drugs (NSAIDs). Today, more than 30 sub- stances are available, ... of salicylate, the rapidly formed metab- olite of ASA, is notable for its dose de- pendence. Salicylate is effectively reab- sorbed in the kidney, except at high uri- nary pH. A prerequisite for rapid renal elimination ... constitutive form present in stomach and kidney; and COX-2, which is induced in inflam- matory cells in response to appropriate stimuli. Presently available NSAIDs in- hibit both isozymes. The search for COX-2-selective...
Ngày tải lên: 24/10/2013, 19:15
Tài liệu Một số thuốc mới chống rối loạn lipid máu (New drugs for the control of dyslipidemia) pdf
... statin khi uèng mét TCNCYH 28 (2) - 2004 Mét sè thuèc míi chèng rối loạn lipid máu (New drugs for the control of dyslipidemia) GS. TSKH. Hoàng Tích Huyền* Nhóm statin ức chế HMG - COA...
Ngày tải lên: 26/02/2014, 03:20
Herbal Antibiotics Natural Alternatives for Treating Drug-Resistant Bacteria doc
... hours. Goldenseal seems best when used for six purposes: for active infections, inflammations, or ulcerations in the gastrointestinal tract, from gums to rectum; for active infections in the sinuses ... David Hoffmann for knowing (and living) that it is essential to risk exposing the deep- est weaknesses of the self for the work that we are here to do to come through. Matthew Wood for having the ... diagnostic system and for being the first to publicly say that Samuel Thompson knew what he was doing. Mary Shelley for bringing the dangers of our times so clearly into story form and into our collective...
Ngày tải lên: 15/03/2014, 09:20
Rifabutin for treating pulmonary tuberculosis (Review) potx
... 150 mg daily for 6 months 2. Rifabutin: 300 mg daily for 6 months 3. Rifampicin: 600 mg daily for 6 months Dose was not adjusted for weight Companion drugs: isoniazid (300 mg daily for 6 months); ... then twice weekly for 4 months 2. Rifampicin: 600 mg daily for 2 months then twice weekly for 4 months Dose was not adjusted for weight Companion drugs: isoniazid (400 mg daily for 2 months then ... disturbance Interventions 1. Rifabutin: 150 mg daily for 9 months 2. Rifampicin: 600 mg daily for 9 months Companion drugs: isoniazid (300 mg daily for 9 months) and ethambutol (20 mg/kg for 9 months) Outcomes 1. Smear...
Ngày tải lên: 29/03/2014, 03:20
Guidance for Industry Acute Bacterial Sinusitis: Developing Drugs for Treatment ppt
... development program and clinical trial designs for drugs to support an indication for treatment of ABS. This guidance does not address the development of drugs for other purposes such as prevention ... current thinking on this topic. For the most recent version of a guidance, check the FDA Drugs guidance Web page at http://www.fda.gov /Drugs/ GuidanceComplianceRegulatoryInformation/Guidances/default.htm. ... therapy for phase 3 clinical trials should use information gathered in earlier clinical development; for example, data from pharmacokinetic and pharmacodynamic studies (including information...
Ngày tải lên: 31/03/2014, 14:21
báo cáo hóa học:" Comparing two intramedullary devices for treating trochanteric fractures: A prospective study" potx
Ngày tải lên: 20/06/2014, 04:20
Báo cáo y học: "clinical review: Devices and drugs for cardiopulmonary resuscitation – opportunities and restraints" pot
Ngày tải lên: 12/08/2014, 20:20
Tài liệu The Acquisition of Drugs and Biologics for Chemical and Biological Warfare Defense - Department of Defense Interactions with the Food and Drug Administration doc
... primary FDA-related function of ASD(HA) for CBW defense is to determine the medical indications of use, both for licensed drugs and IND-classified drugs. Therefore, we conclude that Health Affairs ... biologics for protection against CBW agents and drugs for treating exposure to such agents. In this case, DoD assumes a second responsibility, that of a developer, as the commercial mar- ket for military ... are essential to the acquisition of drugs and biologicals for CBW defense: licensing drugs and biologics for military uses, especially CBW defense; using drugs and biologics classified by FDA...
Ngày tải lên: 17/02/2014, 11:20
Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States pdf
... vs. ZDV for 6 weeks No AP or IP ARV sdNVP vs. ZDV for 6 weeks ã For formula-fed infants only, MTCT was 14.3% in sdNVP arm vs. 14.1% in ZDV arm at 6 weeks (not significant, P = 0.30). For breastfed ... EST. Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States C-6 Reproductive Options for ... week), mother and infant ã MTCT was 5.7% at 6 weeks for AP/IP/PP ZDV + 3TC, 8.9% for IP/PP ZDV + 3TC, 14.2% for IP-only ZDV + 3TC, and 15.3% for placebo (efficacy compared with placebo: 63%, 42%,...
Ngày tải lên: 05/03/2014, 13:20