... [6,7] In this study, Nop53p was isolated in a two-hybrid screen as a protein interacting with Nop17p, which is involved in the early steps of prerRNA processing [28] Nop17p and Nop53p interacted in ... established a functional link between several proteins involved in prerRNA processing The exosome subunit Rrp43p interacts with Rrp46p, Nip7p and Nop17p [10,13,28] Nop17p interacts with Nop58p and ... important role in ribosome biogenesis, possibly related to the exosome function Results Nop53p interacts with the pre-rRNA processing proteins Nop17p and Nip7p Saccharomyces cerevisiae Nop53p,...