Expressionsmuster des apoptoseproteins programmed cell death protein 4 (pdcd4) in urologischen tumoren

... 64 4.1 .4 4.1.5 4. 2 4. 2.1 4. 2.2 4. 2.3 4. 2.3.1 4. 2.3.2 4. 2.3.3 4. 2 .4 4.2.5 Nierenzellkarzinom 67 Pdcd4-Expression in Korrelation zur Differenzierung des Gewebes 67 Pdcd4-Expression ... immunhistochemische Fọrbungen nachzuweisen sind, klinisch effektiv verwertbar 31 1.6 Das Programmed cell death Protein Das Programmed cell death 4, kurz Pdcd4, ist ein Pr...

Ngày tải lên: 19/11/2015, 14:18

... actin cortex under the membrane of blebs in filamin-deficient blebbing cells has not been examined in blebs of cells undergoing cell death Although the proteins involved in the execution of blebbing ... tropomyosin and the actin-bundling protein, a-actinin Finally, myosin is recruited and is concentrated in a few distinct dots along the cortex [4] When examined by scanning...

Ngày tải lên: 29/03/2014, 08:20

... confirmed that L pneumophila multiply within A549 alveolar epithelial cells, resulting in cytotoxicity We investigated the mechanism by which L pneumophila induces cell injury in A549 cells by the TUNEL ... Results Intracellular growth and cytotoxicity of L pneumophila in A549 cells First, we verified the infection and intracellular growth of L pneumop...

Ngày tải lên: 12/08/2014, 15:21

... in apoptosis upon the understanding both of cellular and molecular mechanisms of cell demise, as well as of mechanisms of degenerative diseases, the confusion between apoptosis and programmed cell ... with death domain (FADD) induced caspaseindependent cell death No DNA fragmentation was observed and dying cells showed neither condensation nor fragmentation of cells and...

Ngày tải lên: 07/03/2014, 15:20

... of sucrose by the cocoon of the silkworm, Bombyx mori Insect Biochem 5, 653–657 Glucose oxidase prevents programmed cell death 21 Tucker AS (2010) Salivary gland adaptations: modification of the ... action of an insect steroid hormone in steroid-induced programmed cell death Mol Cell Endocrinol 263, 18–28 Kakei M, Iwami M & Sakurai S (2005) Death commitme...

Ngày tải lên: 15/03/2014, 00:20

... defence regulatory function 4668 Fig Role of EDS1 ⁄ PAD4 ⁄ SAG101 and BON1 ⁄ BAP1 + in cell death and plant pathogen resistance Whereas EDS1, PAD4 and SAG101 are positive regulators of cell death, ... underscores the role of salicylic acid (SA) and jasmonic acid (JA) 4672 WRKY53 that differentially accumulate during leaf senescence [123,124] Targets of...

Ngày tải lên: 16/03/2014, 02:20

... transfection (Fig 6E) 10 1 FL2-H 10 2 10 3 10 1 LQ: 3% 10 0 10 1 FL2-H 10 2 10 3 UQ: 97% LQ: 97% 10 0 10 2 10 3 FL1-H 10 4 10 1 D 10 0 Fig Analysis of ANT1 -silencing on DW dissipation and the effect of the mitochondrial ... ANT1 -silencing According to this hypothesis, we found that ANT1 siRNA-treated cells 10 2 FL1-H 10 3 10 4 10 3 10 4 UQ: 86% 10 3 10 4 L...

Ngày tải lên: 29/03/2014, 09:20

... strategy could then be matched with heterologous vectors that expand and/ or differentiate the primed cells to therapeutically useful effector T cells or, alternatively, with homologous boosting ... death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity Journal of Translational Medicine 2010 8:132 Submit...

Ngày tải lên: 18/06/2014, 16:20

... altogether in the other constructs (B) amino acid sequence of the carboxyterminus of wildtype Bcl-2, Bcl-2 ActA, Bcl-2 cb5 and Bcl-2 ΔTM The amino acids derived from ActA and cb5 are shown in bold ... [15,35]) Alternatively, the exclusive protection by wildtype Bcl-2 may be explained by a combined requirement of Bcl-2 at both mitochondria...

Ngày tải lên: 09/08/2014, 10:20

... modification during programmed cell death in lace plant, Aponogeton madagascariensis (Aponogetonaceae) Am J Bot 2007, 94:1116-1128 Gunawardena AHLAN: Programmed cell death and tissue remodeling in plants ... Fukuda H: Programmed cell death of treachery elements as a paradigm in plants Plant Mol Biol 2000, 44:245-253 Fakuda H, Watanabe Y, Kuriyama H, Aoyagi S, Sugiya...

Ngày tải lên: 11/08/2014, 11:21

... despite the many morphological and biochemical studies of PCD in protozoan parasites, most of the homologs of mammalian molecules involved in cell death signaling are missing in the protozoa and the ... Furthermore, by dissecting the mechanisms and regulation of the staurosporine-induced cell death pathway in Blastocystis may lead to discovery of n...

Ngày tải lên: 16/10/2015, 15:35

... Results Inhibition of PAR-2 expression augments H pyloriinduced cell death and DNA fragmentation in gastric epithelial cells To investigate the relations of PAR-2 expression, cell death, and DNA fragmentation, ... gastric epithelial cells, determined by cell death and DNA fragmentation Inhibition of PAR-2 expression suppresses H pyloriinduced activa...

Ngày tải lên: 18/06/2014, 16:20

... suggesting that CIDEC might be a target of PPARc transactivation These data suggest that CIDEC may not only be a downstream target of PPARc transactivation, but is also likely to be involved in a ... human adipocyte differentiation F Li et al mRNA in 3T3-L1 adipocytes, whereas the expression of a dominant-negative mutant of PPARc results in a decrease...

Ngày tải lên: 23/03/2014, 03:20