Recruitment of mesenchymal stem cells to injury sites

... Komarova et al Journal of Ovarian Research 2010, 3:12 http://www.ovarianresearch.com/content/3/1/12 a means to track malignant tissues or for the delivery of anticancer agents to tumors [2,5-9] Several ... relevance of our strategy in an ovarian tumor model, and showed that the number of modified MSC carriers increased in intraperitoneal tumors Artificial receptor stra...

Ngày tải lên: 20/06/2014, 07:20

... tnecseroulf gniwollof ehT SBP htiw semit eerht desnir erew selpmas ehT Co73 ta h rof sllec eht htiw detabucni erew seidobitna yramirp ehT ylevitcepser ,PAFG rof 002 : dna ESN rof 002 : ta ares ... 001-X notirT %4.0 neht dna ,nim rof enoteca %001 ,nim 01 rof lonahtem %001 dloc eci htiw detaert neht erew yehT erutarepmet moor ta nim 01 rof SBP ni edyhedlamrof %7.3 htiw dexif neht dna SBP ... ll...

Ngày tải lên: 07/08/2014, 18:21

... within a small number of cells in monolayer culture Following injection into NP tissue explants, MSCs stained strongly positive for type II collagen and matrix staining in the vicinity of the injected ... viability/metabolic activity of injected mesenchymal stem cells Photomicrographs representative of caspase immunopositivity and polyAcells mRNA staining in...

Ngày tải lên: 09/08/2014, 01:22

... successfully in case reports and small series, with apparently low acute toxicity [57,63] Long-term safety data are needed Scanty and sometimes contradictory AD animal data are available Although the results ... engineer cartilage, bone, muscle, fat, tendon and neuronal cells; they may serve as cell vehicles for gene therapy; they may enhance engraftment in haematopoietic stem cell transp...

Ngày tải lên: 09/08/2014, 08:23

... differentiation of mesenchymal stem cells (MSCs) The gene-expression (MSCs) profile of mesenchymal stem cells (MSCs; n = 2) was analysed by real-time PCR during their differentiation towards chondrocytes ... expression of chemokines and their receptors during chondrogenic differentiation of mesenchymal stem cells (MSCs) The gene(MSCs) expression profile...

Ngày tải lên: 09/08/2014, 10:20

... Phenotypic profiles of HPB-AML-I The expression of MSC-related antigens in the HPB-AML-I cell line is shown (A) CD45 expression of round-polygonal HPB-AML-I cells (upper) and of the cells, which ... karyotype of HPB-AML-I may include the additional genetic changes, which occurred in vitro during and after the establishment of the cell line Nevertheless,...

Ngày tải lên: 10/08/2014, 10:20

... of MSCs to cancer cells, nature of tumour cells and cancer stem cells, integrity of immune system, number of stem cell passages and site of injection; all can affect the outcome of MSCs use in ... tissues by assessing the gene expression profile of some of the Wnt signaling target genes:cyclin D, PCNA, survivin, b-catenin Methods Ninety albino female rats inbred st...

Ngày tải lên: 10/08/2014, 10:21

... Cell Physiol 2009, 219:563-71 doi: 10.1186/1465-9921-11-91 Cite this article as: Carreras et al., Obstructive apneas induce early activation of mesenchymal stem cells and enhancement of endothelial ... computed by dividing the number of Page of cells counted by the mean value of counted cells in controls Endothelial wound healing assay A wound healing a...

Ngày tải lên: 12/08/2014, 11:22

... this inflammatory and catabolic cascade and demonstrated that curcumin (6) has the capacity to block the action of pro-inflammatory cytokines in the joint thus disrupting the inflammatory cycle inhibit ... intestinal absorption of curcumin is fairly low, mainly due to the fact that curcumin is practically insoluble in water, and that it has a low bio-availability [44,45] Despi...

Ngày tải lên: 12/08/2014, 14:22

... using the two tailed paired t-test or the Mann-Whitney test Results Hypoxia- induced pulmonary arteries remodeling and pulmonary hypertension The hypoxia- induced pulmonary artery hypertension was ... MSCs domiciliation into myocardial infarct area, however only a poor fraction of the cells engrafts the myocardium after systemic infusion [8] Sustained pulmon...

Ngày tải lên: 12/08/2014, 18:20

... CHARACTERIZATION OF THE SECRETION OF MESENCHYMAL STEM CELLS AND ITS RELEVANCE TO CARDIOPROTECTION LAI RUENN CHAI (B.Eng (Hons.)), NTU A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... identified Thesis The specific aims of this PhD project were to identify the active cardioprotective factor of the MSCs secretion and to elucidate t...

Ngày tải lên: 10/09/2015, 08:42

... TRANSPLANTATION OF MESENCHYMAL STEM CELLS FOR THE TREATMENT OF PARKINSON’S DISEASE IN A MOUSE MODEL CHAO YIN XIA MD A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ANATOMY ... MPTP, an acute insult initiates an inflammatory reaction that becomes self sustaining after the initiating agent has disappeared The MPTP model of...

Ngày tải lên: 11/09/2015, 09:05

... Factor GVHD Graft-Versus-Host Disease HaMSC Human Adult Mesenchymal Stem Cells HfMSC Human Fetal Mesenchymal Stem Cells HSC Hematopoietic stem cells HUVEC Human Umbilical Vein Endothelial Cells ... study aims to investigate the factors which may play a role in MSC homing and migration to injury sites The homing mechanism of MSC is hypothesized to be similar to...

Ngày tải lên: 13/10/2015, 15:54

... x List of Abbreviations and acronyms xii Introduction 1.1 Mesenchymal stem cells (MSC) 1.1.1 Definition of stem cells 1.1.2 Criteria of being stem cells ... microlitres xvii INTRODUCTION 1 Introduction 1.1 Mesenchymal stem cells (MSC) 1.1.1 Definition of stem cells Stem cells (SC) are defined functionally as cells that have the capacity to self-renew and...

Ngày tải lên: 16/10/2015, 15:35