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COMPUTATIONAL CHARACTERIZATION FOR GENOME INTEGRATION SITES OF HEPATITIS b VIRUS (HBV) AND GENE TARGETS OF HBV x PROTEIN

COMPUTATIONAL CHARACTERIZATION FOR GENOME INTEGRATION SITES OF HEPATITIS b VIRUS (HBV) AND GENE TARGETS OF HBV x PROTEIN

COMPUTATIONAL CHARACTERIZATION FOR GENOME INTEGRATION SITES OF HEPATITIS b VIRUS (HBV) AND GENE TARGETS OF HBV x PROTEIN

... COMPUTATIONAL < /b> CHARACTERIZATION < /b> FOR < /b> GENOME < /b> INTEGRATION < /b> SITES < /b> OF < /b> HEPATITIS < /b> B VIRUS (HBV) AND GENE TARGETS OF < /b> HBV X PROTEIN LIU LIZHEN (B. Sc (Hons.), NUS) A THESIS SUBMITTED FOR < /b> THE DEGREE OF < /b> ... plots for < /b> the expressions of < /b> the seven potential HBx deregulated gene targets and expressions of < /b> HBx protein in 100 HCC patients 106 x LIST OF < /b> TABLES Table 1.1: Comparison of < /b> metrics and performances ... Computational < /b> Analysis for < /b> Characterization < /b> of < /b> HBV- Host Genome < /b> Integration < /b> Sites < /b> HBV- host genome < /b> integration < /b> is very commonly observed in HBV- associated HCC cases, and is believed to be one of...
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Báo cáo y học:

Báo cáo y học: " A computational approach for genome-wide mapping of splicing factor binding site" pdf

... Berstein and Yonina Eldar for advice on statistical analysis and mathematical formulations This work was supported by the Mallat Family Fund granted to YMG HDE was supported by the Israeli Science ... in Additional data file 1) The optimal set of parameters was: cutoffsig at a P-value of < 0.01, cutoffsub at a P-value of < 0.025, w = 50, and a = Although these were found as optimal parameters, ... normalized expression vector Availability The method presented here is embodied in a software package called Splicing Factor Finder (SFF), which is available in Additional data file as a standalone...
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Báo cáo y học:

Báo cáo y học: " Characterization of Hepatitis B virus (HBV) genotypes in patients from Rondônia, Brazil" doc

... Railway, a hallmark in Rondônia state history, that was built by many African-descendants workers in the beginning of < /b> twentieth century Most of < /b> them had come from the Caribbean Barbados in a different ... states, including Rondônia A deeper characterization < /b> of < /b> hepatitis < /b> B virus genotypes found in Southern Brazil is needed to better understand the migration of < /b> hepatitis < /b> B virus genotypes in Brazil, ... Robertson BH, Locarnini S, Magnius LO: Genetic diversity of < /b> hepatitis < /b> B virus strains derived worldwide: genotypes, subgenotypes, and HBsAg subtypes Intervirology 2004, 47:289-309 Chandra PK, Biswas...
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Báo cáo khoa học:

Báo cáo khoa học: " Hepatitis B virus genotypes and evolutionary profiles from blood donors from the northwest region of China" docx

... part of the tree are the blood donors' numbers; characters in the other part of the tree are serial numbers in GeneBank; characters in the right bracket refer to HBV genotype Page of (page number ... similar subtype using reference sequences, which proves the high mutation rate of HBV A DL2000 10 11 281bp 132bp 109bp Counts of samples B B C D Genotype of HBV Figure of HBV reactive blood donors ... and had higher ALT levels (Table and Fig 1C), which were all beyond the upper limit (20 IU.L-1) for blood donors formulated by China On the other hand, serological marker analysis of HBV in the...
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Báo cáo khoa học:

Báo cáo khoa học: "Survey of both hepatitis B virus (HBsAg) and hepatitis C virus (HCV-Ab) coinfection among HIV positive patients" ppsx

... coinfection and HIV- HBV coinfection and/ or both < /b> are common [1,2] HIV- positive individuals are at risk of < /b> coinfection with HBV and HCV and/ or both < /b> infections [3] Coinfections of < /b> HBV and HCV with HIV have ... 6:202 Background Human immunodeficiency virus (HIV) , hepatitis < /b> B virus (HBV), and hepatitis < /b> C virus (HCV) are major public health concerns Because of < /b> shared routes of < /b> transmission, HIV- HCV coinfection ... prevalence rates of < /b> coinfection of < /b> HBsAg and anti-HCV antibodies and both < /b> HBsAg and anti-HCV in HIV- positive patients were 282 (72%), 57 (14.5%) and 31(7.9%), respectively (Table 1) The rate of < /b> the...
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Báo cáo khoa học:

Báo cáo khoa học: " An overview of molecular epidemiology of hepatitis B virus (HBV) in India" pot

... of < /b> hepatitis < /b> B virus surface antigen mutants in subtype adw in vaccinated Singapore infants Vaccine 2001, 20:639-640 Tanaka Y, Mizokami M: Genetic Diversity of < /b> Hepatitis < /b> B Virus as an < /b> important ... clearly indicates an < /b> impending danger Recently, in contrast to the mainland India, very high rates of < /b> HBsAg have been recorded among certain primitive tribes of < /b> Andaman and Nicobar Islands Studies ... considerably influenced the epidemiology < /b> of < /b> HBV and other parenteral infections in India and specially in the eastern and north eastern parts of < /b> India [51-53] Modes of < /b> HBV transmission in India...
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siRNA, miRNA and their possible roles in molecular therapy of chronic human hepatitis b virus infection and hepatocellular carcinoma

siRNA, miRNA and their possible roles in molecular therapy of chronic human hepatitis b virus infection and hepatocellular carcinoma

... proteins; TP: terminal protein During HBV infection in < /b> human,< /b> virus particles are present in < /b> a large quantity in < /b> patient blood Both infectious and < /b> non-infectious particles can be found in < /b> the ... diagnosis and < /b> treatment of < /b> HCC 1.2 HBV-the Virus and < /b> the Disease HBV is a small enveloped DNA virus which can cause acute and < /b> chronic < /b> infection of < /b> the liver (Robinson, 1994) HBV infection remains a ... antigen HBsAg Hepatitis < /b> B surface antigen HBV Hepatitis < /b> B virus HCC Hepatocellular carcinoma HCV Hepatitis < /b> C virus HIV Human < /b> immunodeficiency virus IFN Interferon IFN-α Interferon alpha IRES Internal...
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Báo cáo y học:

Báo cáo y học: "Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Dual Infection"

... the efficacy of interferon-alpha (IFN-alpha) and ribavirin combination therapy for patients with chronic hepatitis C and B virus (HCV/HBV) coinfection Forty-two chronic HCV/HBVcoinfected patients ... seroclearance Int J Med Sci 2006, 60 Dual Infection of HBV and HCV and hepatocellular carcinoma (HCC) Conflict of interest HBV and HCV infections are confirmed causes of HCC What’s the combined ... References 10 11 12 13 14 Table Coinfection with HBV and HCV and risk of HCC Variables Case number HCC case No HBV(-)HCV(-) HBV(+)HCV(-) HBV(-)HCV(+) HBV(+)HCV(+) 118 184 21 11.2 42.9 42.8 71.4 95%CL...
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Báo cáo sinh học:

Báo cáo sinh học: " Hepatitis B virus (HBV) genotypes in Egyptian pediatric cancer patients with acute and chronic active HBV infection" pptx

... determine the hepatitis < /b> B virus genotypes in Turkish patients with chronic liver disease Their study comprised 25 pediatric and 29 adult patients with chronic hepatitis < /b> B virus infection and genotype ... comprised 22 patients with acute hepatitis < /b> B infection (AH) and 48 with chronic active hepatitis < /b> (CAH) HBV related acute forms of liver disease were diagnosed based on the appearance of hepatitis < /b> B surface ... recently been described which differ by at least 4% [8] The genotypes show a distinct geographical distribution between and even within regions, and are proving to be an invaluable tool in tracing...
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xác định kiểu gen của virus gây viêm gan siêu vi b (hepatitis b virus-hbv) và mối liên quan giữa kiểu gen với một số đặc điểm lâm sàng, cận lâm sàng trên bệnh nhân nhiễm hbv tại đắk lắk

xác định kiểu gen của virus gây viêm gan siêu vi b (hepatitis b virus-hbv) và mối liên quan giữa kiểu gen với một số đặc điểm lâm sàng, cận lâm sàng trên bệnh nhân nhiễm hbv tại đắk lắk

... virus < /b> gây < /b> vi< /b> m < /b> gan < /b> siêu < /b> vi < /b> B b nh nhân nhi m virus < /b> gây < /b> vi< /b> m < /b> gan < /b> siêu < /b> vi < /b> B (HBV) t i khu v c t nh k L k - Xác < /b> nh m i liên quan gi a ki u gen < /b> c a virus < /b> HBV v i m t s c i m lâm sàng c n lâm sàng b nh ... tìm hi u ki u gen < /b> c a virus < /b> gây < /b> vi< /b> m < /b> gan < /b> siêu < /b> vi < /b> B (HBV) 100 b nh nhân nhi m HBV, thu c t l ki u gen < /b> c a HBV c trình b y b ng 3.1 B ng 3.1 T l ki u gen < /b> c a HBV b nh nhân t nh KI U GEN < /b> S lư ng (n ... B GIÁO D C VÀ ÀO T O TRƯ NG I H C TÂY NGUYÊN - TH THÙY DƯƠNG XÁC NH KI U GEN < /b> C A VIRUS < /b> GÂY VI< /b> M GAN < /b> SIÊU VI < /b> B (HEPATITIS B VIRUS-< /b> HBV) VÀ M I LIÊN QUAN GI A KI U GEN < /b> V I M T S C I M LÂM...
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Báo cáo hóa học:

Báo cáo hóa học: " Hepatitis B virus (HBV) genotypes in Egyptian pediatric cancer patients with acute and chronic active HBV infection" ppt

... determine the hepatitis < /b> B virus genotypes in Turkish patients with chronic liver disease Their study comprised 25 pediatric and 29 adult patients with chronic hepatitis < /b> B virus infection and genotype ... comprised 22 patients with acute hepatitis < /b> B infection (AH) and 48 with chronic active hepatitis < /b> (CAH) HBV related acute forms of liver disease were diagnosed based on the appearance of hepatitis < /b> B surface ... recently been described which differ by at least 4% [8] The genotypes show a distinct geographical distribution between and even within regions, and are proving to be an invaluable tool in tracing...
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Báo cáo y học:

Báo cáo y học: " Hepatitis B virus genotypes and precore and core mutants in UAE patients" ppt

... 28 B virus strains derived worldwide: genotypes, subgenotypes, and HBsAg subtypes Intervirology 2004, 47:289-309 Magnius LO, Norder H: Subtypes, genotypes and molecular epidemiology of the hepatitis < /b> ... FJ: Hepatitis < /b> B virus genotypes and precore and core mutants in Brazilian patients J Clin Microbiol 2004, 42:2455-2460 Sanger F, Nicklen S, Coulson AR: DNA sequencing with chainterminating inhibitors ... Detection of BCP and precore mutants For the detection of BCP and precore mutants, HBVDNA-positive samples were amplified by using the primers described by Takahashi et al.[19] Sequencing reaction...
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Báo cáo y học:

Báo cáo y học: "Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon" ppsx

... (and Lys) tend to be over- High density IJISS DNA arrays have been developed for global analysis of Streptomyces gene expression and transcription factor binding The HspR regulatory system of S ... against the test arrays and the probe performance was scored using the following equations Firstly the Cy3 and Cy5 background-subtracted signals, designated 'g' and 'r', respectively, obtained by feature ... chaperone and protease production It is envisaged that these arrays will find widespread use in systems level analysis of Streptomyces coelicolor biology Materials and methods Streptomyces strains and...
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Báo cáo hóa học:

Báo cáo hóa học: " Elective caesarean section versus vaginal delivery for preventing mother to child transmission of hepatitis B virus – a systematic review" pot

... infectivity of < /b> HBV So we only Figure the efficacy of < /b> ECS versus < /b> vaginal < /b> delivery < /b> for < /b> preventing < /b> MTCT of < /b> HBV Analysis of < /b> Analysis of < /b> the efficacy of < /b> ECS versus < /b> vaginal < /b> delivery < /b> for < /b> preventing < /b> MTCT of < /b> HBV ... study was at high risk of < /b> bias and graded as category C Assessment of < /b> publication bias There was an insufficient number of < /b> trials for < /b> us to < /b> assess publication bias Effects of < /b> interventions Assessment ... timing of < /b> elective < /b> caesarean < /b> section < /b> Br J Obstet Gynaecol 1995, 102:101-106 Zanardo V, Simbi AK, Franzoi M, Soldá G, Salvadori A, Trevisanuto D: Neonatal respiratory morbidity risk and mode of < /b> delivery...
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Báo cáo y học:

Báo cáo y học: "miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data" pptx

... of all miR loci in the Ciona genome Altogether, miRTRAP generated an apparent false negative rate of approxi- mately 5% and a false discovery rate of approximately 19% To systematically compare ... endogenous human Argonautes and their miRNA partners in RNA silencing Proc Natl Acad Sci USA 2008, 105:7964-7969 33 Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, ... to other genomes will reveal additional novel miRs Materials and methods Library preparation, sequencing and Northern analysis Ciona stage-specific small RNA library preparation and Illumina sequencing...
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