Gene expression of thyroid hormone receptors TR alpha and TR beta during early development in tilapia, oreochromis mossambicus

... thyroid hormones on TRs was investigated (Chapter 5) Cloning of TR and TR CHAPTER CLONING AND SEQUENCING OF THYROID HORMONE RECEPTORS TR AND TR IN TILAPIA, OREOCHROMIS MOSSAMBICUS 2.1 INTRODUCTION ... TR isoforms, including TR 1, TR 2 and TR 3 from the TR gene and TR 1 and TR 2 from the TR gene (Lazar, 1993) The TR isoforms differ in their c...

Ngày tải lên: 16/09/2015, 12:08

... for the first time, the presence of alternative promoter usage for the MGP gene and provides clear evidence for differential expression of this gene during the very early stages of embryonic development ... maternally inherited, and we provide evidence for the presence of alternative promoter usage in this gene during early X lae...

Ngày tải lên: 30/03/2014, 16:20

... N, Fujii Y, Gonoi T, Miyazaki J, Seino S Cloning and functional characterization of a third pituitary adenylate cyclaseactivating polypeptide receptor subtype expressed in insulinsecreting cells ... not offer any information as to the distribution of PACAP and PAC1 receptor in human placenta at various gestations, during pregnancy In this study, we utilized in situ...

Ngày tải lên: 07/08/2014, 18:21

... of adenomatous polyposis coli (APC), somatostatin, carbonic anhydrase and tenascin C in the cerebellum (Figure 1a) and those of lysyl oxidase, carbonic anhydrase 4, enolase 3β and creatine kinase ... sensitive to thyroid hormone and the primary mode of T3 action is a direct influence on cardiac gene expression [20] Increased heart rate (tachycardia) and myocardial contractility...

Ngày tải lên: 09/08/2014, 20:20

... 5¢-GGAAGAAC CGTGCATTACC-3¢, and labeled with [a- 32P]dCTP using a Megaprime labeling kit (Amersham Pharmacia, Piscataway, NJ, USA) Hybridization signals were detected with a BAS2000 bio-imaging analyzer ... protein Intracellular l-glutamate was assayed by measurement of the concentration of l-glutamate with a l-glutamate determination kit (Yamasa Corp., Chiba, Japan) 2D-PAGE and in...

Ngày tải lên: 16/03/2014, 04:20

... Effect of MTE -I overexpression on steroidogenesis To further explore the role of MTE -I in the regulation of steroidogenesis, we examined the effect of MTE -I 1807 Acyl-CoA thioesterase and synthetase ... these two proteins is the rate-limiting step in steroidogenesis [6] Fatty acyl-CoAs bind to the acyl-CoA- binding protein, which can bind and may thereb...

Ngày tải lên: 16/03/2014, 18:20

... Introduction 1 Introduction to Thyroid Hormone Receptors Aria Baniahmad Biology of Thyroid Hormone Receptors Thyroid hormone receptors (TRs) play a major role in animal physiology ... the super family of nuclear hormone receptors (NHR) These receptors represent hormone- regulated transcription factors Members of NHR include receptors for lipophilic hormones, such as...

Ngày tải lên: 11/04/2014, 10:37

... cells in defined lesional stages Quantification of CCR1, CCR2 and CCR5 mRNA expressing Quantification of CCR1, CCR2 and CCR5 mRNA expressing cells in defined lesional stages Mean numbers of CCR1+ ... expression of CCR1, CCR2 and CCR5 in the spinal cord (data not shown) Enhanced expression of CCR1, CCR2 and CCR5 mRNA was subsequently observ...

Ngày tải lên: 19/06/2014, 22:20

... effects of hypertonic fluid administration on the gene expression of inflammatory mediators in circulating leucocytes in patients with septic shock: a preliminary study Annals of Intensive Care 2011 ... solution was added and the sample incubated, shaking at 37°C for 30 to digest any contaminating DNA A total of μl of Stop solution was add...

Ngày tải lên: 20/06/2014, 23:20

... mechanisms involved in the increase or maintenance of bone mass in OA This study of the IT region of the proximal femur in primary hip OA and non-OA postmortem controls investigated changes in gene expression ... of combining gene expression analysis with histomorphometry allows the exploration of any relationships between gene expression and...

Ngày tải lên: 09/08/2014, 08:23

... prepared from the knee joints of normal rats or from rats days (acute phase) or 20 to 28 days (chronic phase of inflammation) after induction of AIA The patella and the menisci of the joints ... normal knee joints or from acutely or chronically inflamed knee joints from AIA rats FLS cells are key players in the propagation of joint inflamm...

Ngày tải lên: 09/08/2014, 10:20

... protein gene expression profiles of meniscal fibrochondrocytes The x-axis refers to the passage number, and the y- axis to protein gene expression profiles of meniscal fibrochondrocytes the gene expression ... II gene expression profiles of meniscal fibrochondrocytes The x-axis refers to the passage number, and the y- axis to the gene expression fibrochon...

Ngày tải lên: 09/08/2014, 10:21

... analyze the constitutive expression of each of the TLR genes in bronchoalveolar cells and monocytes, TLR gene expression in autologous monocytes was set as 1, and the TLR gene expression of the autologous ... TLR9 on human alveolar macrophages and monocytes Alveolar macrophages and monocytes from healthy donors were analyzed by flow cytometry using phycoery...

Ngày tải lên: 12/08/2014, 14:20

... Seo H: A κ potential role of activated NF-κB in the pathogenesis of euthyroid sick syndrome J Clin Invest 2000, 106:393-402 De Groot LJ: Dangerous dogmas in medicine: the nonthyroidal illness syndrome ... seriously in a prospective randomized trial Competing interests The author(s) declare that they have no competing interests References 334 Wartofsky L, Burman KD: Alterations in...

Ngày tải lên: 12/08/2014, 22:22

... human lymphocytes by HTLV-1 Using long-term liquid culture immortalization assays, we showed that PTHrP and PTH1R were markedly up-regulated during immortalization of T-lymphocytes PTHrP expression ... transforming factor in conjunction with other oncogenes The goal of this study was to investigate the expression of PTHrP, its receptor, and MIP-1α during the early stages...

Ngày tải lên: 13/08/2014, 05:20