support vector machine classification of microarray gene expression data

Ngày tải lên: 23/06/2014, 01:20

Ngày tải lên: 21/06/2014, 20:20

... inducer of uPA gene expression [16]. Decma-induced uPA gene expression is dependent on Erk activation We and others have shown that activation of Erk plays an important role in uPA gene expression ... phos- phorylation. Moreover, expression of silent mutants of Shc isoforms showed that only p46 Shc and p52 Shc res- cued the effect of the siRNA. Overexpression of p66 Shc not only failed to ... increased expression of uPA is directly related to higher tumor growth and metastasis [1]. Several analyses have already made it clear that the expression of E-cadherin and the expression of MMPs are...

Ngày tải lên: 19/02/2014, 05:20

... hoá từ: 2 2 1 m thành ∑ + i i Cm ξ 2 2 1 ^ ] Luận văn Thạc sỹ 28 Support Vector Machine CHƯƠNG 2. SUPPORT VECTOR MACHINE Chương này tác giả sẽ đề cập tới quá trình hình thành và một số ... Discovery in Database Khai phá tri thức trong CSDL KNN K Neighbourhood Nearest K láng giêng gần nhất ODM Oracle Data Mining Khai phá dữ liệu Oracle SVM Support Vector Machine Máy học vector hỗ ... 41 Support Vector Machine 2.4. Một số phương pháp Kernel Trong những năm gần đây, một vài máy học kernel, như Kernel Principal Component Analysis, Kernel Fisher Discriminant và Support Vector...

Ngày tải lên: 19/02/2014, 09:07

... Analysis of gene expression in homocysteine- injured vascular endothelial cells: demonstration of GRP78/BiP expression, cloning and characterization of a novel reducing agent-tunicamycin regulated gene. Semin ... on ASS gene expression via a decrease in the nuclear amount of NF-jB [44]. This illustrates that glutamine may regulate expression of the same gene via different pathways as a function of cell ... suppressed the expression of CHOP mRNA in pig renal epithelial cells lowering growth-cessation signals [86]. Con- versely, depletion of the amino acid induced activation of CHOP gene expression in...

Ngày tải lên: 07/03/2014, 00:20

Ngày tải lên: 14/03/2014, 23:35

... FAD-moiety of purified NifL. On the basis of these data, we postulate that under anaerobic and nitrogen-limited conditions, NifL inhibition of NifA activity is relieved by reduction of the FAD-cofactor ... conformation and nif -gene expres- sion is activated by NifA. In the presence of O 2 or ammonium, NifL antagonizes the activity of NifA resulting in a decrease of nif -gene expression. In K. pneumoniae,the translationally ... reduction of purified MBP– NifL was studied in vitro at room temperature. In the absence of a redox mediator, the FAD cofactor of oxidized MBP–NifL was not reduced by the addition of NADH (data not...

Ngày tải lên: 17/03/2014, 10:20

... regulation; gene expression. Microarray technologies provide the means to measure simultaneously the expression patterns of thousands of genes [1,2]. These expression data and the availability of more ... (short- term) goal of genetic regulation [23,24]. Dealing with the evolutionary optimization of gene expression in mathematical terms requires substantial simplifications in view of the complexity of cellular ... application of theoretical and computational methods. Time resolved tracing of expression levels for large sets of genes has provided evidence that mRNA levels of metabolic enzymes often change...

Ngày tải lên: 17/03/2014, 10:20

... [-option] train_file model_file 6 CHƢƠNG 1: TÌM HIỂU VỀ SUPPORT VECTOR MACHINE 1.1 PHÁT BIỂU BÀI TOÁN Support Vector Machines (SVM) là kỹ thuật mới đối với việc phân lớp dữ liệu, là ... nhau của các quan điểm và sử dụng thuật toán Naïve Bayes (NB), Maximum Entropy (ME) và Support Vector Machine (SVM) để phân lớp quan điểm. Phƣơng pháp này đạt độ chính xác từ 78, 7% đến 82, ... thuật lẫn ứng dụng thực tế. Nội dung cơ bản của luận văn bao gồm Chương 2: Tìm hiểu về Support Vector Machine Chương 2: Bài toán phân lớp quan điểm Chương 3: Chương trình thực nghiệm Phần...

Ngày tải lên: 18/03/2014, 10:25

... through an involvement of Sax2 in the development of morphological structures (e.g. brain circuits) or the regulation of the expression of factors required for the regulation of energy homeo- stasis. ... effect of leptin on NPY expression [24]. Previously, we reported the deregula- tion of NPY and POMC mRNA expression in Sax2 ) ⁄ ) mice during postnatal development [20]. The expression levels of ... affected by lack of Sax2 gene expression AB CD EF Fig. 4. Analysis of blood glucose, insulin and leptin levels of female Sax2 + ⁄ + and Sax2 ) ⁄ ) animals. (A) Blood glucose levels of Sax2 + ⁄ + and Sax2 )...

Ngày tải lên: 28/03/2014, 23:20

... respect to drug mechanisms of action. Gene- drug correlations on the basis of gene expression and drug activity (AT-matrix clustering) We analysed expression profiles of the 1,376 genes plus 40 indi- vidually ... the expression patterns of genes over the 60 cell lines. These correla- tion coefficients were calculated for each combination of a gene and a drug by taking the (normalized) level of expression of ... organ of origin as did the gene expression profiles. The reason is clear: an individual gene can have a major impact on the activities of a large number of drugs but, being just 1 gene out of 1,376,...

Ngày tải lên: 30/03/2014, 13:20

... the framework of Rhetorical Structure Theory (RST). Our method is based on recent advances in the field of statistical machine learning (mul- tivariate capabilities of Support Vector Machines) and ... algorithmic implementation of multiclass kernel-based vector machines. The Journal of Machine Learning Research, 2:265–292. H. Hernault, P. Piwek, H. Prendinger, and M. Ishizuka. 2008. Generating dialogues ... USA. 673 Proceedings of the 47th Annual Meeting of the ACL and the 4th IJCNLP of the AFNLP, pages 665–673, Suntec, Singapore, 2-7 August 2009. c 2009 ACL and AFNLP A Novel Discourse Parser Based on Support Vector...

Ngày tải lên: 30/03/2014, 23:20

Ngày tải lên: 20/06/2014, 01:20

Ngày tải lên: 22/06/2014, 00:20

Ngày tải lên: 22/06/2014, 23:20

Ngày tải lên: 22/06/2014, 19:20

Ngày tải lên: 22/06/2014, 19:20

Ngày tải lên: 22/06/2014, 19:20