Lipid alterations in excitotoxic brain injury

... L-cycloserine modulated increases in 16:0, 18:0 and 20:0 ceramide species and partially reduced kainate-induced cell death The above findings indicate a role of SPT in ceramide increase after kainate injury ... cholesterol metabolism after kainate injury 35 Dysregulation of ceramide metabolism after kainate injury 35 Effect of apolipoprotein D on the neuronal injury after kainate...

Ngày tải lên: 14/09/2015, 10:42

... swelling following head injury or stroke In summary, the present study has revealed the distribution of betaine/ GABA transporter BGT- 1 in normal brain and in excitotoxic brain injury, as well as the ... function in the brain BGT- 1 is capable of transporting both betaine and GABA, as examined in Xenopus oocytes and various cell lines Bu...

Ngày tải lên: 16/09/2015, 15:55

... pathway < /b> activity after traumatic < /b> brain < /b> injury < /b> (TBI) Functional Functional assessment of < /b> mAb 1379 on alternative < /b> complement < /b> pathway < /b> activity after traumatic < /b> brain < /b> injury < /b> (TBI) Relative alternative < /b> ... complement-< /b> mediated neuroinflammatory response after head injury < /b> Background Traumatic < /b> bra...

Ngày tải lên: 19/06/2014, 22:20

... from the injury Magnetic resonance imaging findings in specific critical neurological conditions Traumatic brain injury Conventional magnetic resonance imaging MRI was first used to investigate ... (>21 days) Characteristics Brain swelling Brain swelling Absence of brain swelling Diffuse atrophy and dilatation of the ventricles DWI Hypersignals in the cortex,...

Ngày tải lên: 13/08/2014, 08:20

... results of phase III trials with progesterone in traumatic brain injury In the meantime, the scientific community needs to continue to pursue similar, early phase trials with other candidate neuroprotective ... citation purposes) Schouten JW: Neuroprotection in traumatic brain injury: a complex struggle against the nature of biology Curr Opin Crit Care 2007, 13:134-1...

Ngày tải lên: 13/08/2014, 11:22

... days after brain injury in the intensive glycemic control group This unexpected worsening of mortality is cause for great concern among those who advocate intensive glycemic control in brain ... during the second week after injury in the intensive control group, the preponderance of data points against the use of intensive glycemic control This find...

Ngày tải lên: 13/08/2014, 11:22

... were integrated in the US into a much larger interagency initiative towards ‘an integrated approach to research in psychological health and traumatic brain injury’ This initiative included working ... by NIH-NINDS (NS 042691) and further funded as part of the interagency initiative in the US towards ‘an integrated approach to research in Psychological Health and Traum...

Ngày tải lên: 13/08/2014, 19:20

... attenuated by hypothermia [15] In models of post -traumatic injury, hypothermia has also been shown to reduce BBB permeability Hypothermia may be attenuating BBB permeability by altering matrix ... global ischemia Brain Res Mol Brain Res 2001, 86:34-47 33 Lyeth BG, Jiang JY, Robinson SE, Guo H, Jenkins LW: Hypothermia blunts acetylcholine increase in CSF of traumatically bra...

Ngày tải lên: 13/08/2014, 20:21

... The added value of ordinal analysis in clinical trials: an example in traumatic brain injury Critical Care 2011 15:R127 Submit your next manuscript to BioMed Central and take full advantage of: ... non-significant, those obtained with ordinal analysis were highly significant With ordinal analysis, a 2- to 2.5-fold gain in information density was demonstrate...

Ngày tải lên: 14/08/2014, 08:21

... stress in the normal and parkinsonian brain Ann Neurol 32, S1–S145 Strong R, Mattamal M & Andorn A (1993) Free Radicals in Aging In Free Radicals, the Aging Brain, and Brain lipid composition in postnatal ... procedures Brain lipid composition in postnatal iron-induced mice study At the age of weeks the mice were weaned and the males were placed and raised...

Ngày tải lên: 16/03/2014, 13:20

... and in most reports the involved patient populations are small, these experiences are valuable At present, in the absence of definite proof of the efficacy of decompressive craniectomy in the treatment ... enough for the enlargement of dura in during decompressive craniectomy, and forms a pedicle of temporal fascia that maintains the blood supply Brain...

Ngày tải lên: 25/10/2012, 11:40

... problem with surface cooling is cold injury, causing pressure ulcers and Therapeutic Hypothermia in Brain Injury skin breakdown Surface cooling is less efficient in reducing the temperature of ... Traumatic brain injury (ICP CONTROL) Traumatic brain injury ( outcome) Stroke Fever in patients with neurological injury Subarachnoid hemorrhage- vasospasm prevention Intrao...

Ngày tải lên: 06/03/2014, 23:20

... Effectiveness of a Wii balance board-based system (eBaViR) for balance rehabilitation: a pilot randomized clinical trial in patients with acquired brain injury Journal of NeuroEngineering and Rehabilitation ... Access Effectiveness of a Wii balance board-based system (eBaViR) for balance rehabilitation: a pilot randomi...

Ngày tải lên: 19/06/2014, 08:20

... murine brain: (1) The first part of the experimental study was designed to investigate a potential role of TNF-dependent regulation of intracranial IL-18 expression in a standardized model of ... used as internal control and untreated control animals (n = 10) were analyzed for baseline evaluation of intracerebral cytokine profiles in these mice (2) In the...

Ngày tải lên: 19/06/2014, 22:20

... antibody (1: 1000, Figure mutant mice in GFAP protein a penetrating brain injury The increase vs WT mice afteris delayed in IL-1R1-null The increase in GFAP protein is delayed in IL-1R1null mutant mice ... localization of interleukin-1beta, interleukin -1 receptor antagonist and interleukin-1beta converting enzyme/caspase -1 in the rat brain after peripheral ad...

Ngày tải lên: 19/06/2014, 22:20