severe brain injury in babies

báo cáo hóa học: " Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT) -I/II null mutant mice" doc

báo cáo hóa học: " Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT) -I/II null mutant mice" doc

... stages of brain injury. The significant findings of increased T cell i nfiltrate into the injury site, increased levels of IL-2, prolonged neuronal death surrounding the injury site and increased ... in MT-I/II -/- mice after brain injury and may explain the differences observed in T cell infiltration in MT-I/II -/- mice. Conclusions MT-I/II expression is increased in the brain after brain injury ... the injured brain. During insult to the central nervous system (CNS), metallothionein-I and -II double knockout (MT-I/II -/- )miceshowincreased neuron death or larger injury size after brain injury [1-3]....

Ngày tải lên: 19/06/2014, 22:20

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Báo cáo y học: " Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats" potx

Báo cáo y học: " Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats" potx

... use. Nissl stain and brain injury score Coronal brain sections corresponding to plate 18 and 31 according to the rat brain atlas [21] were examined. The selected brain sections were stained with ... represents two coronal brain sections illustrating the brain injury score of 0, 1, 2, and 3, respectively. E, Pre-treatment with ceftriaxone dose-dependently reduced brain injury scores and ceftriaxone ... (n = 10 in each group) Figure 5 Pre-treatment with ceftriaxone did not increase GLT1 protein expression in neonatal rat brain tissue. A, GLT1 protein expression in P7 rat brain tissue following pre-treatment...

Ngày tải lên: 10/08/2014, 10:20

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Báo cáo khoa học: "Severe brain injury ICU outcomes are associated with Cranial-Arterial Pressure Index and noninvasive Bispectral Index and transcranial oxygen saturation: a prospective, preliminary study" pdf

Báo cáo khoa học: "Severe brain injury ICU outcomes are associated with Cranial-Arterial Pressure Index and noninvasive Bispectral Index and transcranial oxygen saturation: a prospective, preliminary study" pdf

... severe brain injury and receiving multi-modal monitoring have improved survival when compared to ICP and CPP monitoring [17]. The study and lit- erature findings are in support of severe brain ... monitoring is rec- ommended for severe brain injury. There are several limitations of ICP and CPP monitoring: the ICP device is invasive and insertion requires rigorous training [1,2]; distinct ... Ahmad S, Grindlinger GA, Desjardins S: Noninvasive cerebral oximetry in patients with traumatic brain injury. Crit Care Med 2004, 32(Suppl):A104. 11. Jordan KG: Continuous EEG monitoring in the neuroscience intensive...

Ngày tải lên: 13/08/2014, 03:20

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Báo cáo khoa học: "Cerebral perfusion pressure and risk of brain hypoxia in severe head injury: a prospective observational study" ppt

Báo cáo khoa học: "Cerebral perfusion pressure and risk of brain hypoxia in severe head injury: a prospective observational study" ppt

... of Severe Traumatic Brain Injury. Part I: Guidelines for the Management of Severe Traumatic Brain Injury [http://www2.braintrauma.org/guidelines/ downloadbtf_guidelines_management.pdf?BrainTrauma_Session =2a6642d5eb4eaaf3c01adc32623a51]. 20. ... notice. Guidelines for the Management of Severe Traumatic Brain Injury: Cerebral Perfusion Pressure [http:// www2.braintrauma.org/guidelines/downloads/ btf_guidelines_cpp_u1.pdf?BrainTrauma_Session=bc277e4c42 adc2b85c472214f9799620] 22. ... perfusion pressure augmentation with dopamine and norepinephrine on global and focal brain oxygenation after traumatic brain injury. Intensive Care Med 2004, 30:791-797. 24. Steiner LA, Johnston AJ, Czosnyka...

Ngày tải lên: 12/08/2014, 23:20

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Báo cáo khoa học: "SOFA is superior to MOD score for the determination of non-neurologic organ dysfunction in patients with severe traumatic brain injury: a cohort study" doc

Báo cáo khoa học: "SOFA is superior to MOD score for the determination of non-neurologic organ dysfunction in patients with severe traumatic brain injury: a cohort study" doc

... immune mediator production following traumatic brain injury. In Shock, Sepsis, and Organ Failure -Brain Damage Secondary to Hemor- rhagic-Traumatic Shock, Sepsis, and Traumatic Brain Injury: Fifth Wiggers ... dysfunction in severe traumatic brain injury. Crit Care Med 2005, 33:654-660. 3. Zygun DA, Doig CJ: Measuring organ dysfunction. In Yearbook of Intensive Care and Emergency Medicine Edited by: Vincent ... for citation purposes) 14. McKeating EG, Andrews PJ, Signorini DF, Mascia L: Transcranial cytokine gradients in patients requiring intensive care after acute brain injury. Br J Anaesth 1997, 78:520-523. 15....

Ngày tải lên: 13/08/2014, 02:24

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Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"

Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"

... craniectomy in decreasing ICP and improving pr o g n o sis in patients wi th refractory in- tracranial hypertension after TBI. 2-8 Presently, th e European Brain Injury Consortium and Brain Trauma Foundation ... Traumatic Brain Injury Introduction Decompressive craniectomy, which is performed worldwide for the treatment of severe traum a t i c b r a i n injury (TBI), is a surgical procedure in which ... Abstract Refractory intracranial hypertension is a leading cause of poor neurological outcomes in pa- tients with severe traumatic brain injury. Decompressive craniectomy has been used in the management...

Ngày tải lên: 25/10/2012, 11:40

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Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke docx

Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke docx

... reinter- preted in the context of angiogenesis in the brain. Is it possible that some of the acute neurovascular events in the brain after stroke represent an endogenous attempt by the brain ... and dis- ability in developed countries [3]. The initial vascular event leads to energy loss, which triggers activation of multiple brain cell death pathways. In addition to brain injury responses, ... stroke. During the early acute phase of neurovascular injury, blood– brain barrier perturbations should predominate with key roles for various matrix proteases. During the delayed phase, brain angiogenesis...

Ngày tải lên: 18/02/2014, 11:20

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Báo cáo hóa học: " Effectiveness of a Wii balance board-based system (eBaViR) for balance rehabilitation: a pilot randomized clinical trial in patients with acquired brain injury" ppt

Báo cáo hóa học: " Effectiveness of a Wii balance board-based system (eBaViR) for balance rehabilitation: a pilot randomized clinical trial in patients with acquired brain injury" ppt

... ent to play in standing or in sitting position to improve bal- ance control in both conditions. In standing position the patients are required to maintain their soles on the WBB. In sitting position, ... 2011 References 1. BC brain injury association. [http://www.bcbraininjuryassociation.com/ acquired.php]. 2. Nichols-Larsen DS, Clark PC, Zeringue A, Greenspan A, Blanton S: Factors influencing stroke survivors’ ... mean chronicity of 570.9 ± 313.2 days. Etiology of acquired brain injury in this group of patients included severe traumatic b rain injury (TBI) (n = 3), ischemic or hemorrhagic stroke (n = 11),...

Ngày tải lên: 19/06/2014, 08:20

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báo cáo hóa học: " Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia" docx

báo cáo hóa học: " Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia" docx

... inflammatory mediators in IR injury [34]. Recently, 5-LOX has been shown to be involved in ischemic-like injury in neuronal PC12 cells [35]. As in human brain following stroke [7], we found increased expression ... for cytokines, adhesion molecules and iNOS in brain response to ischemia. Brain Pathol 2000, 10:95-112. 33. Juurlink BH, Paterson PG: Review of oxidative stress in brain and spinal cord injury: ... p65 translocation in brain after IR injury As concluded from the data above (Figs. 1E and 2), there is an increased expression of 5-LOX enzyme in the brain after IR injury. Growing evidence suggests...

Ngày tải lên: 19/06/2014, 22:20

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báo cáo hóa học: " Astrogliosis is delayed in type 1 interleukin-1 receptor-null mice following a penetrating brain injury" pptx

báo cáo hóa học: " Astrogliosis is delayed in type 1 interleukin-1 receptor-null mice following a penetrating brain injury" pptx

... mice vs WT mice after a penetrating brain injuryFigure 2 The increase in GFAP protein is delayed in IL-1R1- null mutant mice vs WT mice after a penetrating brain injury. GFAP levels were measured ... fol- lowing penetrating brain injury. The PAR-1 expression was dramatically increased in the WT mice at 3 days post injury (Fig. 3). By contrast, PAR-1 protein was not induced and remained undetectable ... CSPGs and tenascin, are important participants in the wound- healing process. They are expressed at low levels in the normal brain and are induced by injury. In a damaged brain, this increase is...

Ngày tải lên: 19/06/2014, 22:20

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