photophobia light and color in acquired brain injury

Báo cáo khoa học: Benzo[a]pyrene impairs b-adrenergic stimulation of adipose tissue lipolysis and causes weight gain in mice A novel molecular mechanism of toxicity for a common food pollutant doc

Ngày tải lên : 30/03/2014, 11:20

... by low doses of norepinephrine exerted a signiﬁcant inhibition on lipoysis (Fig 1C) The initial step involved in the epinephrine ⁄ norepinephrine-induced lipolytic cascade includes activation ... Thus, B[a]P exerted an inhibitory effect on epinephrine-induced lipolysis both in murine white and brown adipocytes B 10 ANP-induced FFA release (mM mg/prot) Epinephrine-induced FFA release (mM/mg ... lgÆkg)1 epinephrine (d) or saline (s), or (B) 0.5 mgÆkg)1 B[a]P for the indicated times prior to receiving injections of either saline or 0.25 mgÆkg)1 epinephrine Forty-ﬁve minutes after injection...

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BIOTECHNOLOGY MOLECULAR STUDIES AND NOVEL APPLICATIONS FOR IMPROVED QUALITY OF HUMAN LIFE potx

Ngày tải lên : 28/06/2014, 15:20

... camptothecin, vincristine and vinblastine, are obtained from superior plants (Cragg & Newman, 1999), recently some medicines obtained from marine organisms have showed promising results when administered ... denitrification, which involve nitrogen-fixing, nitrifying and denitrifying bacteria, respectively Blue arrows indicate nitrogen fixation, including biological and industrial processes Green arrows indicate ... processes involving nitrifying bacteria, and pink arrows indicate microbial denitrification processes involving denitrifying bacteria Black arrows indicate the flow of each compound in soils The...

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Báo cáo y học: " Ancient, independent evolution and distinct molecular features of the novel human T-lymphotropic virus type 4" pot

Ngày tải lên : 13/08/2014, 05:21

... Recently, the C-terminus of Tax1, but not Tax2, has been shown to contain a conserved PDZ binding domain present in cellular proteins involved in signal transduction and induction of IL2-independent ... nuclear riboprotein A1 binding sites are underlined The pre-gag region and primer binding site (PBS, underlined) are in italics 5105 and 7120 – 7566) to generate a 170 aa protein Tax mRNA is spliced ... 2–6) ing site within the HTLV-4 LTR representing the with Jurkat EMSA using a 32P-labeled probe(lane 1) incubated c-Myb bindEMSA using a 32P-labeled probe representing the cMyb binding site within...

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Báo cáo y học: " Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy" pps

Ngày tải lên : 13/08/2014, 14:20

... emphasis on brain, prostate, pancreatic and colorectal cancers were included in the review Potential applications of curcumin in cancer prevention and therapy Curcumin exhibits in vitro and in vivo ... cancer cells and antitumoral effect on MDA-MB-231 cell xenografts in vivo by inhibiting p21WAP1, survivin and NF-B and its downstream effectors, including cyclin D1 and Bcl-2, and activating caspase ... cell lines and those detected in the patients in clinical settings Clinical trials of curcumin The results from phase I/II clinical trials including the dose-escalation studies with pure curcumin...

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Tài liệu Plug and Play Splitter Architectures Drive Operational Savings doc

Ngày tải lên : 21/12/2013, 07:17

... faster installation of the splitters – ADC’s splitters can be installed in less than five minutes It eliminates time and expense involved in installing each splitter into the FDH while providing ... for connecting each F1 input to the test equipment A considerable amount of time can be spent during initial turn-up with splicing on pigtails and cutting them off again following testing This ... brought into the cabinet and prepped into a splice area New splitters were installed with fiber pigtails that were spliced into one of the F1 fibers This method resulted in slightly less loss and...

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Tài liệu TRADITIONAL AND NOVEL RISK FACTORS IN ATHEROTHROMBOSIS pptx

Ngày tải lên : 12/02/2014, 16:20

... differentiation of EPCs and their homing to sites of vascular injury are complex and involve several mediators and receptors, such as P-selectin glycoprotein ligand-1, CXC chemokine, and integrins (Chavakis ... circulating platelets by inducing a conformational change in the glycoprotein receptors and enabling cross-linking or adhesion via fibrinogen and other adhesive ligands During this process, activated ... key role in modulating vascular tone, responding to neural, humoral and mechanical stimuli by synthesising and releasing vasoactive substances By sending activating signals to circulating inflammatory...

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Traditional and Novel Risk Factors in Atherothrombosis Edited by Efraín Gaxiola pot

Ngày tải lên : 07/03/2014, 20:20

... differentiation of EPCs and their homing to sites of vascular injury are complex and involve several mediators and receptors, such as P-selectin glycoprotein ligand-1, CXC chemokine, and integrins (Chavakis ... circulating platelets by inducing a conformational change in the glycoprotein receptors and enabling cross-linking or adhesion via fibrinogen and other adhesive ligands During this process, activated ... key role in modulating vascular tone, responding to neural, humoral and mechanical stimuli by synthesising and releasing vasoactive substances By sending activating signals to circulating inflammatory...

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Coronary Artery Disease – New Insights and Novel Approaches Edited by Angelo Squeri pdf

Ngày tải lên : 08/03/2014, 00:20

... B-containing lipoproteins by catalyzing the transfer of insoluble esters in the reverse transport of Chol Thus, CETP is involved in maintaining the balance between the LDL-C, ("bad" Chol) and HDL-C ... leucocyte trafficking Chemokine Ligand-18 (CCL18)/pulmonary and activation-regulated chemokine (PARC) is a circulating chemokine that plays a role in injury healing, physiological homing of mononuclear ... Clotting factors II, V, VII; Fibrinogen; Plasminogen activator inhibitor-1; Thrombomodulin; transforming growth factor-β1 Inflammatory response genes lInterleukin-6 and nuclear factor kappalight-chain-enhancer...

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Báo cáo Y học: Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules pptx

Ngày tải lên : 08/03/2014, 09:20

... termed strand transfer HIV-1 IN comprises three independently folding domains; an N-terminal domain, a catalytic core domain, and a C-terminal domain (for a review see [62]) The N-terminal domain, ... cross-linked interfacial peptides The N-terminus of PR is indicated (N) The four-stranded b sheet formed by amino-acid residues at the N- and C-termini of PR is a major binding determinant in the ... domain INs containing either the catalytic core and C-terminal domain [68], or the N-terminal domain and the catalytic core [69] In all structures reported to date, the quaternary structure of IN...

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Báo cáo khoa học: "Formal aspects and parsing issues of dependency theory Vincenzo Lombardo and Leonardo Lesmo" potx

Ngày tải lên : 17/03/2014, 07:20

... in addition to updating T-stack (PUSH(O,T-stack)) and inserting the u-index u8 in the v component as usual, the parser also inserts the u-index u in the IX component to coindex the appropriate ... d-q-ua-d-irhmediately following the dot can be indexed uj This is acknowledged by predicting an item (representing the subtree rooted by that dependent), and inserting a new progressive integer in the fourth ... Ix-index, v-index, T-stack>: Dotted rules are in a number which is a constant of the grammar, but in off-line parsing this number is bounded by O(n) Position is bounded by O(n) Ixindex and v-index...

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Báo cáo khoa học: Investigation of leucine-rich repeat kinase 2 Enzymological properties and novel assays pptx

Ngày tải lên : 23/03/2014, 06:20

... and C-terminus of Roc (COR) regions and a kinase domain Mutations linked to PD are found throughout the protein, including the kinase domain (G2019S and I2020T), the Roc– COR domain (R1441C and ... V S Anand et al interaction domains, including N-terminal ankyrin repeats, a leucine-rich repeat region, and a C-terminal WD40 domain It also contains a GTPase domain composed of Ras ... phosphorylation of residues within their kinase domains to be activated [23], and therefore can act as substrates of kinases, including themselves The S6 ⁄ H4 serine ⁄ threonine kinase, for example, has...

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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx

Ngày tải lên : 23/03/2014, 07:20

... containing inositol lipids and stabilizes the growth factor receptor tyrosine kinases by increasing their half-life following ligand induced endocytosis Such interaction affects cell growth and ... clathrin light chain A (CLTA), and clathrin light chain B (CLTB), and N-methyl-d-aspartate receptor (NMDAR) subunits NR2A and NR2B Various domains, such as the AP180 N-terminal homology domain (ANTH), ... self-associative, resulting in aggregates ⁄ neuronal intranuclear inclusions Aggregates ⁄ neuronal intranuclear inclusions are observed in cell models, brains of transgenic animals, and post-mortem brains of...

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Goethe and the Molecular Aesthetic ppt

Ngày tải lên : 23/03/2014, 13:20

... mean using the information available, gleaning as much from it as they can, and then internalizing it In the mind, the linkage of information processing areas with perceptual brain regions, and ... link between feeling and thinking That link has been grossly neglected in studies in the philosophy of science In an eﬀort to emphasize the objectivity of science, the intuitive aspects of inquiry ... that is, only attracting particular substrates and only allowing them to react in a particular way, there are many diﬀerent enzymes in every cell and in every living thing Since there is such diversity...

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Erectile Dysfunction – Disease-Associated Mechanisms and Novel Insights into Therapy Edited by Kenia Pedrosa Nunes potx

Ngày tải lên : 23/03/2014, 17:20

... nNOS and phospho-eNOS (at Ser-1177 and Thr-495) levels Arginase has been involved in sexual disorders not only in men, but also in women Administration of arginase inhibitors in vitro and in vivo ... parasympathetic and non-adrenergic non-cholinergic nerves (NANC), which in turn promotes vascular and cavernosal relaxation, leading to an increase in blood flow and intracavernosal pressure resulting in ... renin-angiotensin system (RAS), TNF-, MAP Kinases and arginase II are some of the new insights in this field 4.1 Renin-angiotensin system In the past decade, it has become apparent that the renin-angiotesin...

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NUTRITIONAL ASPECTS and CLINICAL MANAGEMENT of CHRONIC DISORDERS and DISEASES doc

Ngày tải lên : 28/03/2014, 22:20

... Systems Protein-calorie Vitamin D Vitamin D, vitamin C Vitamin C Skin Vitamin A or essential fatty acids Vitamin C, vitamin K Niacin Nails Iron Hair Protein-calorie Face Protein-calorie Protein Eyes ... Bolus feeding has also been reported to result in less feeding intolerance and improved weight gain in preterm infants.90 However, in infants with intestinal73 or cardiac disease,92 the continuous ... solution.29 Using 1.7 mmol/dL of calcium and 2.0 mmol/dL of phosphorus in a parenteral solution containing Trophamine and cysteine, investigators were able to attain 65% of intrauterine calcium...

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Báo cáo khoa học: Mechanistic aspects and redox properties of hyperthermophilic L-proline dehydrogenase from Pyrococcus furiosus related to dimethylglycine dehydrogenase⁄oxidase potx

Ngày tải lên : 30/03/2014, 08:20

... function, in that it is always present at the junction with the substrate-binding domain, and not within a domain, as in NADPHbinding proteins [18] The b subunit also contains an ADP-binding motif, and ... evident in the a subunit This motif has been found in both FAD-binding and NADPH-binding proteins, where it forms the fourth b-strand of the Rossman fold and the connecting loop In ﬂavoproteins, ... PutA comprising the FAD-containing proline dehydrogenase domain has been elucidated, and reveals a domain-swapped dimer, with each subunit containing three domains [7] These domains comprise...

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Báo cáo khoa học: Structural aspects and biological properties of the cathelicidin PMAP-36 pot

Ngày tải lên : 30/03/2014, 20:20

... salt-bridging and hydrophobic interactions, has been indicated as an important factor in the membranolytic activity of the human a-helical cathelicidin LL-37 [18,19] In this respect, it is interesting ... antimicrobial and hemolytic activity of both the hydrophobic C-terminal domain and dimerization in PMAP-36 Results and discussion A cDNA sequence encoding a novel cathelicidin of 166 amino acid residues, ... with increasing concentrations of the peptides Again, permeabilization increases in a concentration-dependent manner and is comparable for the two peptides In agreement with timekilling kinetics,...

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Imaging of the Breast – Technical Aspects and Clinical Implication Edited by Laszlo Tabar pptx

Ngày tải lên : 30/03/2014, 22:20

... Aspects and Clinical Implication (color mapping, axial view) (color mapping, axial view) (color mapping, coronal view) (color mapping, coronal view) Fig By using color mapping of post processing ... carcinoma in situ and infiltrative ductal carcinomas originate in epithelial cells, and therefore, areas of fibroglandular tissue with a greater number of cells are at a higher risk during increased ... extramammary (incidental) findings Most incidental findings occured in the liver (51.9%) Other sites were lung (11.2%), bone (7%), and mediastinum (4.2%) Pleural or pericardial effusions were observed in...

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Báo cáo khoa học: Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes Formation of modiﬁed and oxidized particles pot

Ngày tải lên : 31/03/2014, 01:20

... Binding and modification of proteins by methylglyoxal under physiological conditions A kinetic and mechanistic study with N-alpha-acetylarginine, N-alpha-acetylcysteine, and N-alpha-acetyllysine, ... efficacies of glucose and two aldehydes (MG and GA) in inducing lipid and protein oxidation and antioxidant depletion of LDL particles as well as glycation of the apoB protein by measuring specific parameters ... ortho-tyrosine and methionine sulfoxide in human skin collagen is not accelerated in diabetes Evidence against a generalized increase in oxidative stress in diabetes J Clin Invest 100, 839–846 56...

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Báo cáo khoa học: "ON REPRESENTING GOVERNED PREPOSITIONS AND HANDLING "INCORRECT" AND NOVEL PREPOSITIONS" ppt

Ngày tải lên : 31/03/2014, 18:20

... and therefore principled relaxation of the constraints Furthermore, a principled relaxation of the constraints depends in many instances on knowing the relationship between the non-standard and ... be thinking of on the subject/topic of The questioner in (14) may have in support/favor o f in mind In (15) Quayle may have meant we learn by making mistakes In (16), the idiomatic phrase in support ... errors and errors in subject-verb agreement Jensen, Heidorn, Miller, and Ravin (1983:158) note the importance of "relaxing restrictions in the grammar rules in some principled way." Knowing which...

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