Wip1 regulates proliferation of adult neural progenitors through p53 dependent g2 cell cycle control

... WIP1 REGULATES PROLIFERATION OF ADULT NEURAL PROGENITORS THROUGH P53- DEPENDENT G2 PHASE CELL CYCLE CONTROL ZHU YUNHUA 2009 WIP1 REGULATES PROLIFERATION OF ADULT NEURAL PROGENITORS THROUGH P53- DEPENDENT ... the generation of new neural cells in adult olfactory bulb specifically through p53- dependent M phase entry of the cell cycl...

Ngày tải lên: 14/09/2015, 08:43

... the growth of most kinds of cells, promote the proliferation of some types of cells There is increasing evidence that mild hypoxia acts as a potent regulator of various types of stem cells [12] ... of GFP-positive cells was about 70% of that of total neural stem cells after days of transfection (Fig 4A) The expression of HIF-1a was detected by western bl...

Ngày tải lên: 30/03/2014, 04:20

... transplantation of adult- derived neural progenitor and stem cells [39] Self-renewing multipotent neural progenitor and stem cells have been isolated and characterized in vitro, from various regions of the adult ... plasticity of the nervous system Adult- derived neural progenitor and stem cells grafted in the brain promote neuroprotection, by an immunomodulatory...

Ngày tải lên: 08/08/2014, 17:20

... contributions This study was designed by KH and MM Laboratory analysis was performed by KH Data analysis was performed by KH, SY, YJ and MM Samples and data were provided by OK KH and MM wrote the ... Hagiya et al Retrovirology 2011, 8:19 http://www.retrovirology.com/content/8/1/19 RESEARCH Open Access ATF3, an HTLV-1 bZip factor binding protein, promotes proliferation of a...

Ngày tải lên: 13/08/2014, 01:20

... of hCdc6p However, more importantly in the present context, we note that the synthesis of hCdc6p continues through most of the cell cycle Synthesis of hCdc6p during G1 phase is necessary for the ... that about one half of the newly synthesized hCdc6p associated with chromatin during the 2-h label period Rates of hCdc6p synthesis To investigate whether th...

Ngày tải lên: 17/03/2014, 23:20

... over-expression of p21WAF1 inhibits DNMT1 73 3 .1. 1.7 TSA -mediated induction of p21WAF1 results in inhibition of 76 DNMT1 3 .1. 1.8 TSA -mediated induction of p21WAF1 is independent of p53 85 3 .1. 2 Transcriptional ... between DNMT1 and p21WAF1 in the 63 cell cycle 3 .1. 1 .1 3 .1. 1.2 DNMT1 expression in the cell cycle 63 WAF1 in DNA 67 p21WAF1 68 Tran...

Ngày tải lên: 14/09/2015, 14:13

... model 85 4.2 Temporal and spatial expression of nm23- M2 gene 85 4.3 The role of nm23- M2 in dopaminergic MN9D differentiation 87 4.4 The role of nm23- M2 in inducing cell cycle arrest 89 4.5 Further ... MN9D 64 cell differentiation 3.2 3.1.4 Spatial expression of nm23- M2 in MN9D and SH-SY5Y cells 66 3.1.5 Subcellular localization of nm23- M2...

Ngày tải lên: 08/11/2015, 17:09

... devoid of a given essential amino acid Our data suggest that the GCN2 pathway is directly involved in the regulation of amino acid and protein metabolism, as many of the genes involved in these processes ... their biological processes reveals that amino acid limitation regulates groups of genes that are involved in amino acid and pro...

Ngày tải lên: 07/03/2014, 03:20

... result of the E3 ligase activity of this domain The E3 ligase activity of RNF13 was then assayed in CFMs, and the results presented in Fig 4D show that wild-type RNF13 possesses higher E3 ligase ... nonmuscle-specific E3 ligase The key question concerning the mechanism and function of the myostatin RNF13 pathway that remains to be answered involves the...

Ngày tải lên: 29/03/2014, 08:20

... improvement project in adult intensive care units: overview of the Improving Medicine Through Pathway Assessment of Critical Therapy in Hospital-Acquired Pneumonia (IMPACT-HAP) study Critical Care 2011 ... the integrity of data and accuracy of data analysis All authors contributed to analysis and interpretation of data, and to dr...

Ngày tải lên: 14/08/2014, 07:21

... realities of duty-free business at NoiBai International Airport? What should duty-free department to increase the effectiveness of the company s strategy in trading duty-free goods? Whether changes of ... INTRODUCTION OF NOIBAI AIRPORT SERVICES JOIN-STOCK COMPANY, DUTY-REE DEPARTMENT, DUTY-FREE SHOPS, THE FORMATION AND CONCEPTS OF DUTY-FREE BUSINE...

Ngày tải lên: 18/04/2013, 14:39

... Dynamic Reconfiguration of Indoor Combination Networks Through the Use of Patch Panels Alternative Through the Use of Radiofrequency Patch Panel 2000 homes in optical ... 0 - 6 - Dynamic Reconfiguration of Indoor Combination Networks Through the Use of Patch Panels 4:1 Dynamic Reconfiguration Initial Situation Combination of No...

Ngày tải lên: 10/12/2013, 18:15

... Paulsen, C (2006) The Health Literacy of America’s Adults: Results From the 2003 National Assessment of Adult Literacy (NCES 2006–483) U.S Department of Education Washington, DC: National Center ... literacy is a new component of the 2003 National Assessment of Adult Literacy (NAAL) NAAL assessed the English literacy of adults (ages 16 and o...

Ngày tải lên: 14/02/2014, 09:20

... the rate of electron import into the FMN subdomain and the resulting formation of FMNH2 The extent to which KeqA or the rate of FMNH2 formation influences electron flux through the NOS flavoprotein ... NOS, the second electron is provided to the hemedioxy species by a bound H4B cofactor rather than by the flavoprotein domain [16] The H4B radical is th...

Ngày tải lên: 18/02/2014, 11:20