Evaluation of the antioxidant activity of scutellaria baicalensis and its constituents in diabetic rats

... Wistar rats The images were taken under x400 magnification with haemotoxylin staining The intact Langerhan Islets explain the increase in plasma and pancreatic insulin contents despite the administration ... Banting and Charles Herbert Best repeated the work of Von Mering and Minkowski but went a step further to show the reversal of diabetic symptoms in the dogs by giving them an extract from the ... metformin-treated (M), baicalin-treated (B) and metformin + baicalin treated (MB) STZ-induced diabetic Wistar rats The scale bars indicate 0.1 µm The circle indicates the damage to the inner mitochondrial...

Báo cáo lâm nghiệp: "Evaluation of squared timber and log products in the Hyrcanian Forests of Iran" doc

... 4), the amounts of log products increased and the amounts of squared timber declined at the same time As a result, this study shows that the amounts of squared timber products in the Hyrcanian Forests ... mechanized and mechanized logging systems In non-mechanized logging systems, after cutting, felling and delimbing, the logs are cut using manual chainsaws into smaller products such as squared timber, ... harvesting operations changing from non-mechanized logging systems to mechanized logging systems in the said forestlands Therefore, by improving the mechanized logging operations, the log products increased...

Báo cáo khoa học: " Ultrasonographic evaluation of renal dimension and resistive index in clinically healthy Korean domestic short-hair cats" ppsx

... obese and emaciated cats included in this study In summary, renal dimensions and RI measured by Ultrasonographic evaluation of renal dimension and resistive index in clinically healthy Korean domestic ... Determination of renal length and height on the dorsal plane L: length, W: width Ultrasonographic evaluation of renal dimension and resistive index in clinically healthy Korean domestic short-hair ... compared using paired t-test Results Comparison of renal dimensions in different sonographic planes and RIs Renal dimensions measured by ultrasonography in 50 domestic shorthair cats including renal...

báo cáo khoa học: " Preclinical evaluation of KIT/PDGFRA and mTOR inhibitors in gastrointestinal stromal tumors using small animal FDG PET" ppsx

... signalling and therapeutic intervention in a mouse model of gastrointestinal stromal tumors Proc Natl Acad Sci USA 2006, 103:12843-12848 43 Gunawam B: Knock -in murine models of familial gastrointestinal ... gastrointestinal stromal tumours J Pathol 2008, 214:407-409 doi:10.1186/1756-9966-29-173 Cite this article as: Pantaleo et al.: Preclinical evaluation of KIT/PDGFRA and mTOR inhibitors in gastrointestinal ... combination of nilotinib with mTOR inhibitors To date, no one combination of agents has yet been approved as standard GIST treatment in clinical practice However, there is a growing interest in...

Tài liệu Báo cáo khoa học: Inhibitory properties of cystatin F and its localization in U937 promonocyte cells ppt

... dimerization of cystatin F could be a process regulating its inhibitory properties Screening of proteases for their inhibition showed that cystatin F is different from other cystatins, both in terms of ... mutants of cystatin C have been prepared yet to study the effect of incorporating the FEBS Journal 272 (2005) 15351545 ê 2005 FEBS T Langerholc et al Cystatin F in U937 cells Fig Immunolabeling of cystatin ... activity of the enzyme) Dimerization of cystatin F leads to a loss of inhibitory activity (C) Immunoblot of cystatin F run on nondenaturing PAGE Cystatin F (200 nM) was incubated 15 at 37 C in phosphate...

Báo cáo sinh học: " Exact p-value calculation for heterotypic clusters of regulatory motifs and its application in computational annotation of cis-regulatory modules" doc

... confirmed individual bicoid binding sites in these sequences, these sequences not contain clusters of bicoid binding sites Assessment of gene regulation Enhancers may contain clusters of TF binding ... Individual regulatory segment of DNA can contain many binding sites for several factors, often substantially overlapping with each other [5] This brings about a problem of studying of co-occurring motifs ... probability of observing similar site arrangements in a random sequence This idea of evaluating the statistical significance of heterotypic clusters of sites was implemented in many programs including...

Studies of vortex breakdown and its stability in a confined cylindrical container 1

... RECONMMENDATIONS 15 7 PUBLICATIONS 15 9 ACHIEVEMENT 16 1 REFERENCES 16 2 iv SUMMARY A combined experimental and numerical study on vortex breakdown structure and its dynamic behavior in a confined cylindrical ... LC1 state at Re = 2760 and Λ = 1. 704, and (b) an LC2 state at Re = 2750 and Λ = 1. 780, (each state is asymptotically stable) 81 xii Fig 5 .12 Variation of ΔE0 with Re for (a) LC1 and (b) LC2, at ... for vortex breakdown, and the concave shape of the streamsurfaces of a confined swirling flow may be considered as an additional characteristic of vortex breakdown They argued that the swirling...

Studies of vortex breakdown and its stability in a confined cylindrical container 2

... the analysis of the flow dynamics, as well as allowing still image to be captured via a frame grabber card in a PC For some cases, a high resolution still digital camera was also used to obtain ... the data was sampled and acquired over about 20 minutes, Re is nominally constant For those cases with fixed Reynolds number and varying Λ, rotation rate of the top disk was re-adjusted to account ... disk has a maximum excursion of 0.040 mm (about 0.03º) and a nominal gap of 0.40 mm between the rotating plate and the cylinder The disk was driven by a microstepper motor operating at 20 ,000...

Studies of vortex breakdown and its stability in a confined cylindrical container 3

... experimental results Table presents the values and locations of three local maxima and minima of ψ and η at H/R = 2.5 and Re = 2494 with constant rotating speed The finite differential results ... rotating end 34 CHAPTER NUMERICAL SIMULATION METHOD Two kinds of rotating motions were considered: a constant rotation only and a constant rotation with a superimposed sinusoidal modulation In all ... is adopted, with the origin at the centre of the rotating end wall and the positive-z axis pointing towards the stationary endwall R H z Ω θ r Fig 3. 1 Flow configuration in a confined cylinder...

Studies of vortex breakdown and its stability in a confined cylindrical container 4

... in a low aspect ratio container? This part of the investigation aims to see if an S-shape vortex structure or a spiraltype vortex breakdown can be also produced in a low aspect ratio container ... vortex breakdown, with the upstream and smaller bubble eventually disappears In contrast, the shrinking downstream bubble resulted in the formation of a helical instability of increasing wavelength ... R of 87.25 mm, and a matching rotating disk at the top and a stationary disk at the bottom of the cylinder The height H of the flow domain, and the aspect ratio Λ = H/R, can be varied by moving...

Studies of vortex breakdown and its stability in a confined cylindrical container 5

... visualization can capture the oscillating frequency of the flow as shown above, hot-film was chosen in the following study as it has an added advantage, particularly in the vicinity of Hopf and ... bifurcations, the same strategy as in the numerical work of Marques et al (2002) was adopted in this study, i.e., once a desired state was obtained at a particular point in (Λ, Re) parameter space, ... Fig 5. 30 Hot-film data (time series over minute and corresponding the amplitude of the FFT results) taken at times as indicated, starting with an LC1 state at Re = 2700 and Λ = 1. 757 and increased...

Studies of vortex breakdown and its stability in a confined cylindrical container 6

... spatial discretization, utilizing a Galerkin-Fourier expansion in the azimuthal coordinate θ and Chebyshev collocation in r and z The radial dependence of the variables is approximated by a Chebyshev ... equations (Mercader, Net and Falqués 1991) In this study, the aspect ratio Λ was fixed at 2.5 and variations in Re, A and ωf were considered 96 spectral modes in z, 64 in r, and up to 24 in θ ... QUENCHING OF UNSTEADY VORTEX BREAKDOWN Fig 6. 12 Phase portraits (with Wa and Ww as the horizontal and vertical axes, respectively) at Re = 2800, Λ = 2.5, ωf = 0.5 (ωf /ω0 ≈ 2.88) and A as indicated...

Studies of vortex breakdown and its stability in a confined cylindrical container 7

... was set at 2600 and below with the modulation amplitude A varying from 0.005 to 0.04, and the aspect ratio Λ was maintained at a constant value of 2.5 throughout Note that all flow visualization ... bifurcation is at Re = 271 0, and the second and third occur at Re = 3044 and 3122 Of course, the Hopf frequencies vary with parameters (Re and Λ, as well as A and ωf), but these variations are ... essentially steady, with the streamlines virtually identical to those of the A = steady state shown in Fig 7. 1, and all the oscillations are concentrated in the bottom and sidewall boundary layers...

Studies of vortex breakdown and its stability in a confined cylindrical container 8

... useful in applications where unsteady vortex breakdown is prevalent, such as the tail buﬀeting problem 156 CHAPTER CONCLUSIONS AND RECOMMENDATIONS 8. 2 Recommendations A confined cylindrical container ... Mechanics, Vol 599, No 3, pp441-464, 20 08 Y.D Cui, T.T Lim and H.M Tsai, “Blowing and suction effects on vortex breakdown in an enclosed cylindrical container , Paper AIAA 2007-4360, 37th AIAA ... (forcing) stabilize the flow or not 1 58 PUBLICATIONS LIST OF RELATED PUBLICATIONS T.T Lim and Y.D Cui, “On the generation of a spiral-type vortex breakdown in an enclosed cylindrical container ,...

Tài liệu Báo cáo khoa học: Delineation of exoenzyme S residues that mediate the interaction with 14-3-3 and its biological activity ppt

... these questions using a strategy of single amino acid site-directed mutagenesis Delineation of ExoS residues of the cofactor interaction domain within ExoS Various single mutant ExoS proteins ... study study study study study 639 Delineation of ExoS residues L Yasmin et al Fig Interaction of GST-ExoS variants with endogenous 14-3-3 proteins HeLa cells were harvested and lysates were subjected ... strategy for its interaction with 14-3-3 that is similar to that seen with R18 and serotonin N-acetyltransferase This is because R18 is also nonphosphorylated and serotonin N-acetyltransferase selectively...

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