... genomic context: exonic miRNA in noncoding transcripts, intronic miRNAs in noncoding transcripts, and intronic miRNAs in protein-coding transcripts [8,9] Based on the accumulating knowledge on miRNA ... unprocessed pri -miRNAs However, expression of the marker (regardless of the placement location) could only occur at the expense of failure of cleavage of primiRNA by Drosha [8,9] In contrast and in summary, ... contrast and in summary, the RNAi expression vectors we describe here, pSM155 and pSM30, which are designed based on knowledge of miRNA and RNA splicing, provide a FEBS Journal 273 (2006) 5421–5427...