Computational identification of novel MicroRNAs using intrinsic RNA folding measures

... Analysis of Known MicroRNAs Shows Sexually Dimorphic Expression 81 6.2.4 Computational Identification of Novel MicroRNAs 83 6.2.5 Northern Blot Validation of Novel MicroRNAs ... COMPUTATIONAL IDENTIFICATION OF NOVEL MICRORNAS USING INTRINSIC RNA FOLDING MEASURES NG KWANG LOONG STANLEY (M.Eng (Research), National University of Singapore) (B.Eng (Hons),...

Ngày tải lên: 11/09/2015, 16:05

... Nagasaki M, Nakayama-Hamada M, Kawaida R, Ono M, et al.: Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis Nat Genet ... 327:202-211 Iwaki-Egawa S, Matsuno H, Yudoh K, Nakazawa F, Miyazaki K, Ochiai A, Hirohata S, Shimizu M, Watanabe Y: High diagnostic value of anticalpastatin autoantibodies in rh...

Ngày tải lên: 09/08/2014, 08:23

... linkers, amplification of targeted DNA, purification of amplified DNA, labeling, hybridization, and scanning The Affymetrix GeneChip® Human Mapping 500K Array was used Scanning and analysis were performed ... subsequently genotyped in patients with Behçet's disease and controls using a case-control genetic association approach and the TaqMan SNP Genotyping Assays (Applied Biosys...

Ngày tải lên: 09/08/2014, 14:20

... ebf4 ebf1 ebf2 cyp1a1 cyp1a2 cyp1b1 ) Figure Phylogenetic distribution of stem cell markers and their close paralogs in four protein families Phylogenetic distribution of stem cell markers and their ... undergone repeated gene duplication events for a phylogenetic analysis of the evolution of proteins involved in stem cell function By sequence similarity analysis,...

Ngày tải lên: 14/08/2014, 08:20

... mammals and yeast, is not straightforward in plants Similarly, studying cooperative TFBSs within regulatory modules also suffers from the inclusion of potentially false-positives when selecting genes ... identified using twoway clustering Additional data file is a table giving an overview of the 139 cis -regulatory modules Additional data file is a table showing the mot...

Ngày tải lên: 14/08/2014, 17:22

... Importantly, 86 tags of those expressed differentially correspond to novel transcripts Regulation of expression by -catenin of novel transcripts identified by SAGE Many of the genes involved in dorso-ventral ... of at least 86 novel transcripts with differential expression in the dorso-ventral axis Interestingly, the expression of three transcripts...

Ngày tải lên: 14/08/2014, 21:20

... Mean and standard deviation of the error in the prediction of the three gait events, HL (heel lift), TO (toe off) and HS (heel strike), expressed as %Gait cycle for sock-only condition Mean and ... publication on acceptance doi:10.1186/1743-0003-8-32 Cite this article as: Preece et al.: Automatic identification of gait events using an instrumented sock Journal of Neu...

Ngày tải lên: 19/06/2014, 08:20

... “Application of Higher Order Spectra for the Identification of Diabetes Retinopathy Stages”, Mar, 2008 3) Archaya U.R., Ng E.Y.K., Chang Y.H., Yang J., Kaw G.J.L., “ComputerBased Identification of Breast ... Athina P.P., John M.R., Higher Order Spectra Based Deconvolution of Ultrasound Images”, May 1995 34) Vinod C., Daryl N., Sridha S., "Speaker Identification Usi...

Ngày tải lên: 14/07/2014, 11:49

... meticulously dissected air pouch membranes, we identified several genes relating to innate immunity that were induced strongly by MSU crystals Four of the six factors whose upregulation by MSU crystals ... methods Air pouches Figure 1a outlines the sequence of events of the air pouch experiments Air pouches were raised on the backs of 6- to 8week-old female BALB/c mi...

Ngày tải lên: 09/08/2014, 10:23

... identified and experimentally validated examples of putative novel exons from five genes (Figures S4, S5, S6 and S7 in Additional file 1) Such exons could possibly add novel coding regions and thereby ... RefSeq genes and numerous novel TRs The vast majority of novel TRs was found within or in the vicinity of known genes and thus extends existing gene models, mai...

Ngày tải lên: 09/08/2014, 20:22

... are expressed in baboon liver and lymphocytes and the differences in these miRNA expression profiles The findings from these studies are relevant to future studies of the roles of miRNAs in dyslipidemia ... putative baboon miRNAs After identifying the baboon miRNAs in- silico, we determined expression profiles of baboon liver and lymphocytes miRNAs using a...

Ngày tải lên: 10/08/2014, 05:21

... to be as potent as 5-Aza in terms of demethylation but with much lower cytotoxicity Azacytidine and 5-Aza have been approved for the treatment of myelodysplastic syndromes by FDA, and they are ... Segura-Pacheco B, Trejo-Becerril C, Perez-Cardenas E, Taja-Chayeb L, Mariscal I, Chavez A, Acu a C, Salazar AM, Lizano M, Dueñas-Gonzalez A: Reactivation of tumor suppressor genes by the ca...

Ngày tải lên: 10/08/2014, 05:21

... component of the transcriptome Science 2005, 309(5740):1567-1569 doi:10.1186/1471-2229-11-141 Cite this article as: Jiao et al.: Identification of novel maize miRNAs by measuring the precision of precursor ... miRNA precursors the location of the new miRNA precursors in maize genome 15 16 Additional file 2: secondary structure of the newly identified miRN...

Ngày tải lên: 11/08/2014, 11:21

... regions of influenza a virus polymerase gene segments are critical for efficient viral RNA packaging J Virol 2008, 82:2295-2304 25 Obayashi E, Yoshida H, Kawai F, Shibayama N, Kawaguchi A, Nagata K, ... Full factorial analysis of mammalian and avian influenza polymerase subunits suggests a role of an efficient polymerase for virus adaptation PLoS One 2009, 4:e5658 Skehel J: A...

Ngày tải lên: 11/08/2014, 21:22

... present a systematic approach for the identification of novel, serologically reactive markers of infection (in this case: VZV) The knowledge about the VZV serostatus is extraordinarily important for ... Pinto et al.: A systematic approach for the identification of novel, serologically reactive recombinant VaricellaZoster Virus (VZV) antigens...

Ngày tải lên: 12/08/2014, 04:20