identification of tumor antigens using subtraction and microarrays
Báo cáo y học: "Identification of target antigens of antiendothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach" potx
Ngày tải lên :
12/08/2014, 17:22
... pathophysiology of GCA and the ongoing inflammatory process in the arterial wall The combined use of 2-DE and immunoblotting offers an interesting approach to the identification of target antigens of autoantibodies ... and HUVECs in the sera of patients with GCA and identified their target antigens by using a 2-D immunoblotting technique and MS Few studies have focused on perturbations of the humoral immune ... Supplemental Table S2 Antigens specifically recognised by IgG of three-fifths of the pools of sera from giant cell arteritis patients Additional file 5: Mass spectrometry data of target antigens recognised...
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Tài liệu Identification of Promising Naval Aviation Science and Technology Opportunities docx
Ngày tải lên :
12/02/2014, 19:20
... prioritization of the work to be done and allocation of resources, and (6) the design of a transfer plan for the transition of each technology to a user All of these tasks are, of course, interrelated, and ... Director of Weapons Systems in the Office of the Secretary of Defense Research and Engineering, the Sea Trial Director of the Navy Warfare Development Command, and the Deputy Assistant Secretary of ... Department of the Navy, Washington, D.C., July; and Hon Gordon England, Secretary of the Navy, ADM Vern Clark, USN, Chief of Naval Operations, and Gen James L Jones, USMC, Commandant of the Marine...
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Structural investigation of silicon nanowires using GIXD and GISAXS evidence of complex saw tooth faceting
Ngày tải lên :
16/03/2014, 15:37
... respectively the real and measured angles between ~ and the vertical and u the angle between the normal of the facet and the q CCD plane tions of Ross et al in [5] which show that only one out of two sides ... sidewall morphology and Ross et al [5] with saw-tooth faceting They interpret this faceting term of both the role of the geometry and surface energy of the wire and the liquid droplet, and report that ... provide evidence of the hexagonal cross-section of the wires The angle between two streaks is 60° and the directions of the six sides of the nanowires can be deduced from the directions of these streaks...
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báo cáo hóa học:" Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients" potx
Ngày tải lên :
18/06/2014, 15:20
... 0.01) and Mel/ noM-A sequences (p < 0.05) Furthermore, the majority of Mel/M-A and Ctrl/M-A CDR3 were 12 amino acid long (32.9% and 31.9% respectively), while most of CDR3 of Mel/noM-A and Ctrl/HLA-A2+ ... was found in Melan-A-specific CTL isolated from PBL and from tumor sites of HLA-A2+ melanoma patients, independently of the stage of disease and of the methodological approaches used for T-cell ... the acquisition and alignment of sequences, in the analysis and interpretation of data, and helped to draft the manuscript LC, BP, PGN, and PN, have been involved in drafting and critically revising...
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Báo cáo hóa học: " Automatic identification of gait events using an instrumented sock" docx
Ngày tải lên :
19/06/2014, 08:20
... Mean and standard deviation of the error in the prediction of the three gait events, HL (heel lift), TO (toe off) and HS (heel strike), expressed as %Gait cycle for sock-only condition Mean and ... collection, processing and in some aspects of the experimental design and EL and BF were involved in the development of the experimental set up including the design and manufacture of the instrumented ... aspect of the shank, calcaneous and dorsal aspect of the midfoot Although previous studies have recommended using a shank marker plate with underwrapped bandage [27], pilot work showed us that a bandage...
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foundations of 3d graphics using jogl and java3d
Ngày tải lên :
03/07/2014, 16:08
... OpenGL command, we often omit the interface handle Here we set the physical size of frame and make its contents visible Here the physical size corresponds to the number of pixels in x and y direction ... Scan-conversion, and Clipping generate a random line with -1
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ECE 574: Modeling and Synthesis of Digital Systems using Verilog and VHDL ppsx
Ngày tải lên :
11/07/2014, 02:21
... Applications of LFSRs include generating pseudo-random numbers, pseudo-noise sequences, fast digital counters, and whitening sequences Both hardware and software implementations of LFSRs are ... count from to 77 on a negative edge of the clock and then restart at ECE574: VHDL and Verilog Modeling and Synthesis 12/08/10 Question [20 marks]: An FPGA running off its own local 100MHz oscillator ... after an access time of tacc from OE and CE Write operation (CE and WE valid - write data on the rising edge of WE) In the model check that the address bus is stable for taddr and the data bus is...
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Automated identification of breast cancer using higher order spectra
Ngày tải lên :
14/07/2014, 11:49
... ?/access/helpdesk/help/toolbox/images/radon.htmlandhttp://www.google.com sg/search?hl=enandclient=firefox-aandchannel=sandrls=org.mozilla%3AenUS %3Aofficialandhs=Oqandq=radon+transform +of+ an+imageandbtnG=Search andmeta=andaq=fandoq= ... ?/access/helpdesk/help/toolbox/images/f2125938.htmlandhttp://www.google.com.sg/search?hl=enandclient=firefoxaandchannel=sandrls=org.mozilla%3Aen-US%3Aofficialandhs=oTVandq=[R %2Cxp]+%3D+radon%28IMAGE%2Ctheta %29andbtnG=Searchandmeta=andaq=fandoq= ... /helpdesk/help/techdoc/ref/fitsread.htmlandhttp://www.google.com.sg/search ?hl=enandclient=firefox-aandchannel=sandrls=org.mozilla%3Aen-US %3Aofficialandhs=04aandq=fitsreadandbtnG=Searchandmeta=andaq=fandoq = 18) [last...
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Báo cáo nghiên cứu khoa học: " BUILDING A GOOD IMAGE FROM TWO COLOR IMAGES OF CAMERA MODEL USING GA AND DISCRETE WAVELET TRANSFORM" pptx
Ngày tải lên :
22/07/2014, 02:21
... sets of data before fusing and forming a new set of data DWT is one of popular tools used in MRA by using low-pass and high-pass filter [6, 7, 8] Consider is DWT performance, the analysis and ... 10 Histogram and standard deviation comparisons (a), (c), (e) are histograms and standard deviation corresponding to R, G, B color of image 9a; (b), (d), (f) are histograms and standard deviation ... 11 Histogram and standard deviation comparisons (a), (c), (e) are histograms and standard deviation corresponding to R, G, B color of image 9b; (b), (d), (f) are histograms and standard deviation...
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Báo cáo khoa học: " Investigation of tumor hypoxia using a twoenzyme system for in vitro generation of oxygen deficiency" pot
Ngày tải lên :
09/08/2014, 09:20
... generation and control of hydrogen peroxide independently of the degree of hypoxia [34,42] Since reactive oxygen species play an important role during tumor growth and radiation therapy of tumors, ... on the outcome of cancer treatment and the prognosis of the disease Tumor hypoxia affects the behaviour of tumor cells and is associated with poor prognosis and reduced overall survival [16] This ... conception and design of the study, drafted the manuscript and gave approval of the final version VA, GM, UW, CS and SR were involved in data analysis and data interpretation AA, UH, JD, SM and PEH...
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Báo cáo y học: "Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane" pot
Ngày tải lên :
09/08/2014, 10:23
... Sokoloff L, Wolfe F: Development of criteria for the classification and reporting of osteoarthritis Classification of osteoarthritis of the knee Diagnostic and Therapeutic Criteria Committee of ... the design and coordination of the study, including supervision of the bioinformatic analyses RWK contributed to the design and coordination of the study and participated in the writing of the manuscript ... degradation of extracellular matrix (ECM) components, and invasion of cartilage and bone [2,4] as well as fibrosis of the affected joints [9] The extended analysis of gene expression profiles in...
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Báo cáo y học: " Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity" ppt
Ngày tải lên :
09/08/2014, 23:20
... proportion and eventually a majority of the tumor cells The extent of the proliferative advantage and the time between occurrence of the aberration and tumor collection influence the proportion of tumor ... It handles samples with aneuploidy, presence of normal cells and facilitates detection of tumor cell heterogeneity We describe allele-specific copy number profiling of lung cancer cell lines and ... signal and copy number Tumor Aberration Prediction Suite We present a tool and algorithm for allele-specific copy number analysis of tumor samples on Affymetrix 500K and SNP 6.0 arrays called Tumor...
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báo cáo khoa học:" Identification of clinically significant psychological distress and psychiatric morbidity by examining quality of life in subjects with occupational asthma" pot
Ngày tải lên :
12/08/2014, 00:20
... correlation between general and different subscale scores on the AQLQ(S) on the one hand and, on the other hand, levels of psychological distress and rates of psychiatric disorders, and the extent to which ... asthmaspecific quality of life and standard measures of psychological distress, and moderate correlations between impaired asthma-specific quality of life and psychiatric morbidity (i.e., mood and anxiety ... between 0.1 and 0.3, medium between 0.3 and 0.5 and high between 0.5 and Receiver operator characteristic (ROC) curve and Youden Index (YI) In order to determine the best cut-off level of the AQLQ...
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Báo cáo sinh học: "An automated stochastic approach to the identification of the protein specificity determinants and functional subfamilies" pot
Ngày tải lên :
12/08/2014, 17:20
... of specificity groups and identify SDPs using the SDPlight procedure Then we consider each sequence of the MSA as a sequence of unknown specificity, and use SDPprofile to reassign it to one of ... shown in [20], and reflects proximity of two distributions, in our case, the gold standard and the predicted grouping of sequences In the case of generated families we have the standard of truth given ... given a random model, set of positions and call them SDPs, for these are the positions that correlate best with grouping of sequences by specificity The second component of the method is SDPprofile,...
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Báo cáo y học: " Identification of a novel resistance (E40F) and compensatory (K43E) substitution in HIV-1 reverse transcriptase" doc
Ngày tải lên :
13/08/2014, 06:20
... Results Association of the E40F and K43E changes with NRTItreatment and resistance To better understand the role of the E40F and K43E substitutions we analyzed the frequencies of these substitutions ... 40 and 43 in reverse transcriptase was determined Shown are the percentages of the specified amino acid change of all mutations at that position (pct of mut) and in the total population (pct of ... value of 0.15 or greater, an odds ratio of > and FDR of 0.01 were considered to be co-varying Discussion In the present study the reasons for appearance of two novel changes at codon 40 and 43...
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Báo cáo sinh học: "Identification of Mendelian inconsistencies between SNP and pedigree information of sibs" pot
Ngày tải lên :
14/08/2014, 13:21
... 5.9, 64.1, and 173.9, respectively (i.e by subtracting the number of animals correctly deleted by PAROFF); sum of the number of animals deleted by PAR-OFF and SIBCOUNT (or SIBREL); sum of the type ... farms in Ireland, the UK, the Netherlands and Sweden, as well as sires of some of the genotyped cows The quality control criteria for selecting the final set of SNP were a call rate of > 95%, a ... line) of the number of opposing homozygotes between pairs of: A all animals, B parent-offspring pairs, C half-sibs and D full-sibs Figure - Distributions of sib relationships Empirical (‘bars’) and...
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IDENTIFICATION OF A MINIMAL CIS-ELEMENT AND COGNATE TRANS-FACTORS REQUIRED FOR THE REGULATION OF RAC2 GENE EXPRESSION DURING K562 CELL DIFFERENTIATION
Ngày tải lên :
24/08/2014, 12:22
... melting of the DNA TFIIH has kinase and helicase activity The kinase activity of this factor is required for the phosphorylation of the C-terminus domain (CTD) of Pol II that consists of repeats of ... H19 and Kcnq1ot1 (Li, Beard et al 1993), activation of all X chromosomes due to the demethylation of Xist (Beard, Li et al 1995), and an increase in rates of loss of heterozygosity because of ... 27, 36 and 79 in H3 and on position 20 in H4 (Nakayama, Rice et al 2001) Methylation of histone H3K4 and H3K36 are associated with activation of transcriptional activity, and histone H3K9 and H3K27...
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MODELING OF OPENCAST MINES USING SURPAC AND ITS OPTIMIZATION
Ngày tải lên :
04/11/2014, 09:21
... work and had also made a comparative study on which module of particular software is user friendly and easy to learn and the accuracy of results obtained from them A detailed review of mining softwares ... ࢙࢚ࢇ࢚࢛࢙ሺ࢚ሻ, 1≤i≤N and 1≤j≤M (1) where, National Institute of Technology, Rourkela-769008 Page 20 Si(t) = demand of shovel I for dumpers Θij(t) = ability of dumper j to respond to the demand of shovel ... Manno, Switzerland Ronson K.A, 2001, Computerized open pit planning and the development and application of a software open pit planner Sattarvand J, Delius C.N, 2008, Perspective of meta-heuristic...
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Computational identification of novel MicroRNAs using intrinsic RNA folding measures
Ngày tải lên :
11/09/2015, 16:05
... feature for the ith random sequence of rn; n and n are the sample mean and the standard deviation of the feature S(sn) for R random RNA sequences rn The entire set of R random sequences rn is ... Expression profiles of 88 known miRNAs and novel miRNAs expressed across six miRNA Libraries Adult Testis and Ovary (ATE and AOV); Juvenile Testis and Ovary (5WT and 5WO); Juvenile Male and Female ... Availability of Datasets and Software 42 Chapter Unique Folding of Precursor MicroRNAs: Quantitative Evidence and Implications for De Novo Identification 43 4.1 Comparison between Vertebrate and...
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