Genomic discovery of recurrent CD44 SLC1A2 gene fusion in gastric cancer

... 3.4.2 Recurrent CD44- SLC1A2 fusion in gastric tumor samples 113 3.4.3 Confirmation of CD44/ SLC1A2 genomic inversions in fusion 116 positive primary gastric tumors 3.4.4 Tumors expressing high SLC1A2 ... of chromosomal inversion model of CD4 4SLC1A2 gene fusion in SNU16 89 Figure 3.6 Protein expression of CD44- SLC1A2 92 Figure 3.7 CD44- SLC1A2 si...

Ngày tải lên: 09/09/2015, 18:49

... of gastric cancer cells to HDAC inhibitors……………… ……113 6.2 The heterogeneous response of gastric cancer cell lines to HDAC inhibitors……………………………………………………………………………………… …………114 6.3 HDAC inhibitors ... treatment of cancer, HDAC inhibitors will be applied into more and more clinical trial of different type of cancers Thus it is necessary to understand the resis...

Ngày tải lên: 10/09/2015, 09:06

... http://www.wjso.com/content/8/1/71 Figure The feeding tube in the wrong location into the fistula duct absolute restriction of oral route and the administration of antibiotics From the point of view of the nutritional assistance ... towards the use of enteral nutrition in these cases is not because enteral nutrition per se, but basically because of the...

Ngày tải lên: 09/08/2014, 03:22

... patients in total that had died COX-2, VEGF-C and D2-40 expression in gastric carcinoma Positive expression of COX-2 protein and VEGF-C showed as a yellow or brownish yellow stain in the cytoplasm of ... immunoreactivity for COX-2 and VEGF-C Immunoreactivity of D2-40 proteins was found in the cytoplasm and cellular membrane of lymphatic Figure Immunohistoc...

Ngày tải lên: 10/08/2014, 10:21

... 8.95) These cut-offs are arbitrary and chosen because they resulted in about half of the genes falling into 'average' gene expression and the remainder of the genes falling roughly equally into ... and that inclusion of these genes in the analysis may obscure an effect Thus, we repeated the analysis with the 500 genes with the strongest differences in...

Ngày tải lên: 14/08/2014, 20:22

... 3 1 1 1 1 )4 71, +467 )4 71 )4 71, )1 16 )3 96 )3 48 )3 48 )3 18, +109, +201 )2 67 )2 19, )1 38, +206 )1 53 )5 3 )5 2 )5 2 +222 +260 +423 +465 +466 a Numbers refer to the position of the 5¢-end of the conserved ... throughout the brain tissue in R6/1 compared to R6/2 mice [29,30] The differences between the two transgenic line...

Ngày tải lên: 16/03/2014, 18:20

... this publication, we extended our assessment by analyzing the frequencies of IVS2 +C691G locus in intron of OPRM1 gene and G543A SNP in HRH2 gene in Vietnamese, using PCR-RFLP method These results ... understanding the origins of interindividual variation in response to mu-opioid receptor ligands and in diseases of substance dependence The OPRM1 gene enc...

Ngày tải lên: 22/03/2014, 09:20

... stimulating factor receptor dedicator of cytokinesis guanylate binding protein 2, interferon-inducible chemokine (C-C motif) ligand 18 interleukin receptor suppressor of cytokine signaling chemokine ... 1.33 4.14 ± 0.80 3.01 ± 1.10 6.00 ± 1.85 integrin beta binding protein Integrin, alpha integrin, alpha integrin, alpha X Integrin, beta Integrin, beta Integrin, beta 0.63 ± 0.06 0.39 ± 0.2...

Ngày tải lên: 18/06/2014, 18:20

... stimulating factor receptor dedicator of cytokinesis guanylate binding protein 2, interferon-inducible chemokine (C-C motif) ligand 18 interleukin receptor suppressor of cytokine signaling chemokine ... 1.33 4.14 ± 0.80 3.01 ± 1.10 6.00 ± 1.85 integrin beta binding protein Integrin, alpha integrin, alpha integrin, alpha X Integrin, beta Integrin, beta Integrin, beta 0.63 ± 0.06 0.39 ± 0.2...

Ngày tải lên: 20/06/2014, 01:20

... 313 contains the extra C, which could cause the HCV RNA polymerase to accidentally create the deleted versions of the 5'UTR However, of our isolates containing the extra C' s, only 313T1 had variants ... map of the 313 plasma consensus sequence is shown The extents of the large deletions found in 313 plasma are shown by the outlining The inset shows th...

Ngày tải lên: 20/06/2014, 02:20

... Cervidae, the same family as red deer and The PRNP gene in wild ruminants from Italy and Scotland 119 Fig The phylogenetic tree of similarity among the PRNP gene sequences of the analysed wild ruminants ... total of 323 red deer samples were collected from Scotland (n = 132; 82 from the mainland and 50 from the Isle of Rhum) and during th...

Ngày tải lên: 07/08/2014, 23:22

... expressions in peripheral blood mononuclear cells in vitro The expression of 15 IFI genes (IFIT1, IFIT3, IFIT5, IFI6, IFI16, IFI27, IFI30, IFI35, interferon-induced transmembrane protein 1, ISG15, IRF7, ... repressive effect on the expressions of most IFI genes in PBMCs in vitro in this experiment The relative expressions of three of the representative genes (t...

Ngày tải lên: 09/08/2014, 01:22

... expressions in peripheral blood mononuclear cells in vitro The expression of 15 IFI genes (IFIT1, IFIT3, IFIT5, IFI6, IFI16, IFI27, IFI30, IFI35, interferon-induced transmembrane protein 1, ISG15, IRF7, ... repressive effect on the expressions of most IFI genes in PBMCs in vitro in this experiment The relative expressions of three of the representative genes (t...

Ngày tải lên: 09/08/2014, 13:22

... article as: Zhang et al.: Effects of DNMT1 silencing on malignant phenotype and methylated gene expression in cervical cancer cells Journal of Experimental & Clinical Cancer Research 2011 30:98 ... treatment Conclusions In conclusion, our study demonstrates that DNMT1 silencing could suppress proliferation and induce apoptosis of Hela and Siha cells...

Ngày tải lên: 10/08/2014, 10:21

... with dysgeusia, and an obvious facial droop appeared The remainder of his neurological examination, including contralateral facial strength, remained unchanged A brain magnetic resonance imaging ... to induce acute worsening including facial neuropathy Only one previous similar report, of two clinical cases, was identified Chida et al reported in 1998 two cases of bilateral f...

Ngày tải lên: 11/08/2014, 03:21