Palladium(II) catalyzed oxidative functionalization of c h bonds using alkyne as building block

... reactions Scheme 2.1 Pd -catalyzed cascade reactions of 4-hydroxycoumarins with internal alkynes Scheme 2.2 Cyclic ketone as substrate Scheme 2.3 Plausible mechanism Scheme 2.4 Plausible mechanism Scheme ... Pd(II)/Pd(IV) catalytic cycle Scheme 1.13 X-ray structures of Pd(IV) complexes Scheme 1.14 Pd(II)/Pd(IV) catalytic cycle Scheme 1.15 C- H bond arylation via Pd(II)/Pd(IV) cataly...

Ngày tải lên: 09/09/2015, 11:25

... Cp*Ir(CO) (H) (p -C6 F4 CF3) OC F Ir F H F CF3 F 26 Cp*Ir(CO)(COOH)(p -C6 F4 CHO) OC F Ir F O OH F C F O H xii 27 Cp*Ir(CO)(COOH)(p -C6 F4 NO2) OC F Ir F O F OH NO2 F 28 Cp*Ir(CO) (H) [2,4 -C6 F3 (CN)2] OC NC Ir F H F CN F ... 14a = Rh 14b Cp*Ir(CO)(η2 -C6 F6 ) Ir CO F F F F F F x 16 [Cp*Ir (C6 F5 )(μ-CO)]2 O Ir Ir F F F O F F F F F...

Ngày tải lên: 13/09/2015, 19:48

... levels of c-Fos, c-Jun, or BimEL, and did not affect hepatocyte apoptosis (Figs and 5) These results indicate that c-Fos and c-Hun are crucial for BimEL expression and induction of hepatocyte apoptosis ... Ishihara et al Regulation of BimEL expression by c-Fos A (a) (b) B C (c) (a) (b) Fig Suppression of BimEL expression by knockdown of c-Fos...

Ngày tải lên: 06/03/2014, 00:21

... al P450 coumarin dealkylation isotope effects Table Kinetic isotope effects for 7-OR coumarin O-dealkylation by purified P450s estimated by MS Kinetic isotope effect Intermolecular competitive P450 ... system, human liver microsomes Results and discussion Intramolecular kinetic isotope effects The intramolecular kinetic isotope effects measure the...

Ngày tải lên: 16/03/2014, 13:20

... The Chemistry of C-C π-Bonds - - Alkene and Alkyne chemistry I  Alkene chemistry Structures and influence of orbitals on reactivity: How alkenes react and why? Typical reactions of alkenes: ... reduction of the alkene  The Chemistry of C-C π-Bonds - 18 - Alkynes Alkynes have two π-bonds that are orthogonal R1 R1 R2 R2 See Prof Dixon’s course for methods t...

Ngày tải lên: 22/03/2014, 20:20

... 2.8 31( 4) 1. 85 1. 97 1. 91 1.66 2 .13 1. 88 1. 98 2.02 1. 97 1. 75 2.28 1. 76 1. 98 1. 82 1. 94 1. 86 2.07 2.04 2 .19 1. 93 2. 01 2 .16 1. 87 1. 90 15 4 15 5 15 4 15 7 14 6 17 4 16 5 15 8 14 8 13 9 13 9 16 7 14 8 16 7 17 3 17 2 16 2 ... 16 2 13 8 14 5 16 4 15 6 14 6 17 0 16 4 x,y,z x +1, y,z x +1, y,z 1- x,y +1 ⁄ 2,-z x,y,z x,y,z x,y,z x,y,z x -1,...

Ngày tải lên: 30/03/2014, 20:20

... relationship between the narrator and Tante Atie? a They are sisters b They are friends c Tante Atie is the narrator’s guardian d Tante Atie is the narrator’s mother b Tante Atie is the narrator’s ... because of the character’s tragic flaw (though the character often tries to blame fate) A tragic flaw is a characteristic that drives the character to make a poor decisio...

Ngày tải lên: 18/06/2014, 17:20

Ngày tải lên: 05/08/2014, 09:46

Ngày tải lên: 05/08/2014, 10:20

... Regulation of activity and expression of NHE 1 54  1. 4.4 A  1. 4.4 B  1. 5  Regulation of NHE -1 activity 54  Transcriptional regulation of NHE -1 expression .58  AIM OF STUDY 61 ... response repression of NHE -1 expression .11 1  Figure 13 : Thiol oxidizing agent diamide mimicked the effect of H2O2 in the downregulation of NHE -1 gene expression 11 3  Figu...

Ngày tải lên: 14/09/2015, 08:50

... where A3 f 2→ A4 f 3→ A5 f 4→    O2 A6 → A7  A0 = A = {O1 .a , O1 .A} , A1 = {O1 .a , O1 .A, O2 .A} , A2 = { O1 .a , O1 .A, O2 .A, O1.b, O1.c }, A3 = {O1 .a , O1 .A, O2 .A, O1.b, O1.c, O3 .a} , A4 = ... F ∪ O Put A0 = A, A1 = t1 (A0 ), , Am = tm(Am-1), and D (A) = Am, we have A0 ⊆ A1 ⊆ ⊆ Am = D (A) ⊆ M A problem A → B on a network (O,F) is called solvable...

Ngày tải lên: 18/09/2012, 10:13

... đ c CH CHO + H O 170oC OH OH to b CH3-COO-CH=CH2 + NaOH R–COO–R’ + NaOH R–COONa + R’–OH to Ví dụ 11: Viết phản ứng sau: a CH2Cl-COO-CHCl2 + NaOH b HCOO-CHCl2-CH2Cl + NaOH °R–COO–R’ + NaOH to ... đẳng andehyt CH2= CH-CHO là: A (C2 H3 -CHO)n C B CnH2n-3CHO CnH2n+1CHO D D CnH2n-1CHO CnH2n+2-2a-m(ch c) m Adehyt đề cho chưa no c 1lk C= C, ch c °a=1 ⇒ ⇒ ° m =1 CnH2n-1CHO Ví dụ 5: Viết CT...

Ngày tải lên: 19/09/2012, 14:38

... of the dansyl derivative and the N-ethyl-diisoproylamine and the dansyl sulfamidoethylamine to the tetrazine product linked with 5-dansyl sulfamidoethylcarboxamide-2-yl For the syntheses of the ... [15] The synthesis of the tetrazine dicarbonic acid derivate was performed as described by [15] The synthesis procedure of the corresponding dansyl derivative was ca...

Ngày tải lên: 25/10/2012, 11:00